01273nas a2200169 4500008004100000022001400041245022200055210006900277260011000346300001400456520041200470100002400882700002500906700002300931700001800954856013100972 2005 eng d a1359-734500aConcomitant dimorphs of tri-O-[p-halobenzoyl]-myo-inositol 1,3,5-orthoformates with different halogen bonding contacts: first order crystal-to-crystal thermal phase transition of kinetic form to the thermodynamic form0 aConcomitant dimorphs of triOphalobenzoylmyoinositol 135orthoform aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcOCT a5870-58723 a

Crystallization of tri-O-[p-halobenzoyl]-myo-inositol 1,3,5-orthoformates from ethyl acetate-petroleum ether solution produced concomitant dimorphs that have different halogen bonding contacts; the kinetic form with C-(BrO)-O-...-C contacts upon heating to 185 degrees C, converts completely to the thermodynamic form with C-(BrOLC)-O-... contacts via crystal-to-crystal first order phase transition.

1 aGonnade, Rajesh, G.1 aBhadbhade, Mohan, M.1 aShashidhar, M., S.1 aSanki, A., K. uhttps://library.ncl.res.in/content/concomitant-dimorphs-tri-o-p-halobenzoyl-myo-inositol-135-orthoformates-different-halogen-101255nas a2200193 4500008004100000022001400041245014900055210006900204260010600273300001400379490000700393520043000400100001200830700002400842700002500866700002100891700002200912856012700934 2006 eng d a0040-403900aCu(I)-catalyzed cycloaddition of constrained azido-alkynes: access to 12- to 17-membered monomeric triazolophanes incorporating furanoside rings0 aCuIcatalyzed cycloaddition of constrained azidoalkynes access to aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcAPR a2775-27780 v473 a

A strained monomeric 12-membered triazolophane was formed by the Cu(I)-catalyzed intramolecular cycloaddition of an azide to an alkyne having a constrained tether incorporating ail aromatic ring and a furanoside ring. Similar cycloadditions of azido-alkynes having ester, furanoside and peptidic tethers led to the formation of monomeric triazolophanes of higher ring sizes. (c) 2006 Elsevier Ltd. All rights reserved.

1 aRay, A.1 aManoj, Kochunnoonny1 aBhadbhade, Mohan, M.1 aMukhopadhyay, R.1 aBhattacharjya, A. uhttps://library.ncl.res.in/content/cui-catalyzed-cycloaddition-constrained-azido-alkynes-access-12-17-membered-monomeric-001589nas a2200169 4500008004100000022001400041245016300055210006900218260011000287300001200397490000700409520079500416100002401211700002501235700002701260856013201287 2008 eng d a1466-803300aCrystal-to-crystal transformation amongst dimorphs of racemic 2,6-di-O-(p-halobenzoyl)-myo-inositol 1,3,5-orthoformates that achieves halogen bonding contacts0 aCrystaltocrystal transformation amongst dimorphs of racemic 26di aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcFEB a288-2960 v103 a

{Racemic 2,6-di-O-(p-halobenzoyl)-myo-inositol 1,3,5-orthoformates (bromo (1) and chloro (2)) produced two polymorphs each, thin needle type crystals (Form I) were obtained from methanol, whereas larger rectangular crystals (Form II) were produced from ethyl acetate. Both forms could be produced concomitantly on crystallization (of 1 or 2) from ethyl acetate-light petroleum ether mixture; the yield of Form II crystal was always much more compared to Form I crystals. Although, a one-dimensional isostucturality linking molecules via O-H center dot center dot center dot O hydrogen bonding is seen in both forms, the difference arises in linking these chains. In larger Form II crystals (of 1 and 2), the adhesions are via halogen bonding (C-X center dot center dot center dot O=C

1 aGonnade, Rajesh, G.1 aBhadbhade, Mohan, M.1 aShashidhar, Mysore, S. uhttps://library.ncl.res.in/content/crystal-crystal-transformation-amongst-dimorphs-racemic-26-di-o-p-halobenzoyl-myo-inositol-001688nas a2200265 4500008004100000022001400041245010200055210006900157260005700226300001200283490000700295520075000302653001701052653002201069653002501091653001301116653003001129653001701159653003001176100002401206700002401230700002501254700002301279856012001302 2010 eng d a0022-476600aConformational polymorphism in racemic 2,4-Di-o-Benzoyl-6-o-Tosyl myo-Inositol 1,3,5-Orthoacetate0 aConformational polymorphism in racemic 24DioBenzoyl6oTosyl myoIn a233 SPRING ST, NEW YORK, NY 10013 USAbSPRINGERcAUG a725-7300 v513 a

The title compound, C(29)H(26)O(10)S, yields two conformational polymorphs concomitantly from dichloromethane-methanol mixture; the major polymorph grows as plates (Form I, monoclinic, P2(1)/n) and the minor polymorph grows as needles (Form II, triclinic, P-1). The two forms differ mainly in orientation of the tosyl group. In Form I, sulfonyl oxygen of the tosyl group makes intermolecular C -HaEuro broken vertical bar O interactions, whereas the same group in Form II is involved in an intramolecular short dipolar S=OaEuro broken vertical bar C=O (sulfonyl-carbonyl) contact. The molecular organization and the influence of various weak non-covalent interactions that stabilize these conformers in the crystal lattices are discussed.

10aConformation10acrystal structure10adipolar interactions10aInositol10anon-covalent interactions10apolymorphism10asulfonyl-carbonyl contact1 aManoj, Kochunnoonny1 aGonnade, Rajesh, G.1 aBhadbhade, Mohan, M.1 aShashidhar, M., S. uhttps://library.ncl.res.in/content/conformational-polymorphism-racemic-24-di-o-benzoyl-6-o-tosyl-myo-inositol-135-002128nas a2200169 4500008004100000022001400041245014200055210006900197260011000266300001200376490000700388520135800395100002401753700002501777700002701802856012901829 2010 eng d a1466-803300aCrystal-to-crystal thermal phase transition amongst dimorphs of hexa-O-p-toluoyl-myo-inositol conserving two-dimensional isostructurality0 aCrystaltocrystal thermal phase transition amongst dimorphs of he aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcSEP a478-4840 v123 a

Triclinic (P-1) crystals of hexa-O-p-toluoyl-myo-inositol obtained from common organic solvents exhibited single crystal-to-single crystal irreversible phase transition centered at similar to 250 degrees C. The transformation of these crystals to monoclinic P2(1)/n form was revealed using DSC and X-ray diffraction studies. The latter crystals could also be produced by melt crystallization. Crystal structure analysis revealed that the molecules in both forms are linked via bifurcated C-H center dot center dot center dot O interactions to make almost identical centrosymmetric dimers. The neighbouring dimers are bridged via C-H center dot center dot center dot O and aromatic pi center dot center dot center dot pi stacking interactions to create two-dimensional isostructural assemblies. The difference in the two crystal forms arises from linking of the centrosymmetric dimers along the third dimension; the dimers are centrosymmetrically bridged in the triclinic form, while they have n-glide relationship in the monoclinic form. Comparison of the dimorph structures further revealed that they are actually an excellent case of morphotropism since dimorphs are related by non crystallographic rotation and translation of their basic motif (centrosymmetric dimers) that transforms the triclinic (P-1) phase to a monoclinic (P2(1)/n) phase.

1 aGonnade, Rajesh, G.1 aBhadbhade, Mohan, M.1 aShashidhar, Mysore, S. uhttps://library.ncl.res.in/content/crystal-crystal-thermal-phase-transition-amongst-dimorphs-hexa-o-p-toluoyl-myo-inositol-0