01503nas a2200193 4500008004100000022001400041245011300055210006900168260007100237300001600308490000700324520074800331100002301079700002201102700002101124700001701145700002201162856012501184 2010 eng d a0888-588500aRu(II) phenanthroline complex as catalyst for chemoselective hydrogenation of nitro-aryls in a green process0 aRuII phenanthroline complex as catalyst for chemoselective hydro a1155 16TH ST, NW, WASHINGTON, DC 20036 USAbAMER CHEMICAL SOCcDEC a12180-121840 v493 a

Ru(II) Phenanthroline [Ru(II)(Phen)(n) where n = 1,2,3] complexes were used as highly chemoselective catalysts for hydrogenation of nitro aryls using molecular hydrogen in an aqueous media. Water, universal solvent, was used as a reaction mixture for hydrogenation of nitro-aryls to make the process green. The chemoselectivity in hydrogenation of substituted nitrobenzene to substituted aniline was obtained as high as >99% at about complete conversion of substituted nitrobenzene. The parametric effects, including effect of solvent, effect of ligand, effect of metal to ligand ratio, effect of temperature and pressure, were studied in detail to obtain the best results. The Ru(Phen)(n) was characterized by FTIR, UV-vis, and XPS.

1 aDeshmukh, Amit, A.1 aPrashar, Atul, K.1 aKinage, Anil, K.1 aKumar, Rajiv1 aMeijboom, Reinout uhttps://library.ncl.res.in/content/ruii-phenanthroline-complex-catalyst-chemoselective-hydrogenation-nitro-aryls-green-002098nas a2200241 4500008004100000022001400041245012000055210006900175260000800244300001200252490000700264520120300271653002901474653002001503653004301523653004701566653003301613653000901646100002601655700002101681700002901702856012501731 2024 eng d a0360-319900aReaction kinetics for catalytic hydrogenation of quinoline to decahydroquinoline as liquid organic hydrogen carrier0 aReaction kinetics for catalytic hydrogenation of quinoline to de cNOV a102-1120 v923 a

The catalytic hydrogenation of quinoline to decahydroquinoline (DHQ) formation is studied for various parameters such as temperature, hydrogen pressure, reaction time, solvents, reactant-to-solvent ratio, and catalyst loading over 5%Pd loaded on alumina (Pd/Al2O3) to obtain optimal reaction conditions. The hydrogen uptake of quinoline in the liquid phase reaction using isopropylalcohol (IPA) is studied in an autoclave reactor. The optimum reaction parameters of 50 bar H2 pressure and 175oC with reactant to solvent ratio of 1:9 for reaction time of 5 h are observed. The effect of IPA solvent showed that hydrogen uptake of 6.91 wt% with complete hydrogenation of quinoline and DHQ yield of more than 99% is observed. The reaction kinetic model is developed for a simplified reaction mechanism and is simulated using the Markov Chain Monte Carlo (MCMC) simulation tool to predict the rate constants and the experimental observations are validated with the model predictions. The activation energy for quinoline hydrogenation to py-THQ formation is estimated to be 136.57 kJ/mol. It is envisaged that quinoline hydrogenation to pz-THQ is the rate-limiting step in the DHQ formation.

10aDecahydroquinoline (DHQ)10aHydrogen uptake10aLiquid organic hydrogen carrier (LOHC)10aMarkov chain Monte Carlo (MCMC) simulation10aThermal screening unit (TSU)10atool1 aBagwan, Farahanaz, M.1 aKinage, Anil, K.1 aVasireddy, Satyam, Naidu uhttps://library.ncl.res.in/content/reaction-kinetics-catalytic-hydrogenation-quinoline-decahydroquinoline-liquid-organic01595nas a2200205 4500008004100000022001400041245012900055210006900184260000800253300001400261490000700275520082600282100002901108700003001137700002301167700002801190700002501218700002101243856012501264 2025 eng d a1477-052000aRongalite-promoted self-dimerization of 3-acylidene-2-oxindoles: a diastereoselective route to synthesis of bispirooxindoles0 aRongalitepromoted selfdimerization of 3acylidene2oxindoles a dia cOCT a8687-86940 v233 a

A facile and efficient one-pot rongalite-mediated self-dimerization of 3-acylidene-2-oxindoles has been developed for the diastereoselective synthesis of highly functionalized dispirocyclopentanebisoxindoles. The reaction proceeds via a domino sequence involving intermolecular Michael addition followed by intramolecular aldol cyclization under basic conditions. Rongalite, an inexpensive and readily available reagent (similar to\$0.03 per g), plays a crucial role in promoting the transformation, offering significant advantages such as operational simplicity, step economy, scalability to gram-scale synthesis, and potential for post-functionalization. This methodology provides an efficient route to structurally complex oxindole frameworks with high stereocontrol, demonstrating broad synthetic utility.

1 aChaudhari, Suryakant, S.1 aNichinde, Chandrakant, B.1 aPatil, Baliram, R.1 aGirase, Amardipsing, S.1 aKaulage, Sandeep, H.1 aKinage, Anil, K. uhttps://library.ncl.res.in/content/rongalite-promoted-self-dimerization-3-acylidene-2-oxindoles-diastereoselective-route01883nas a2200253 4500008004100000022001400041245010100055210006900156260000800225300001100233490000700244520100500251653002901256653003001285653002001315653002301335653002201358653002701380100002601407700002401433700002101457700002901478856012201507 2026 eng d a0930-751600aReaction kinetics for dehydrogenation of decahydroquinoline to quinoline for hydrogen generation0 aReaction kinetics for dehydrogenation of decahydroquinoline to q cFEB ae701770 v493 a

Catalytic dehydrogenation of decahydroquinoline (DHQ) to quinoline is a promising pathway for hydrogen release in liquid organic hydrogen carrier systems. In this work, solvent-free DHQ dehydrogenation over Pd/Al2O3 is systematically investigated to evaluate hydrogen release performance and reaction kinetics. High DHQ conversion (83.9%) and degree of dehydrogenation (82.7%) are achieved at optimal reaction conditions. A power-law kinetic model based on a simplified reaction mechanism is developed and simulated using a Markov Chain Monte Carlo (MCMC) approach for estimation of rate constants and validation of concentration profiles with experimental data. The apparent activation energies are determined to be 45.85 kJ/mol for DHQ to 5,6,7,8-tetrahydroquinoline (bz-THQ) and 185.43 kJ/mol for bz-THQ to quinoline formation, identifying latter as the rate-limiting step. This framework provides mechanistic insight and supports the potential of DHQ as an efficient hydrogen carrier.

10aDecahydroquinoline (DHQ)10adegree of dehydrogenation10aDehydrogenation10arate-limiting step10aReaction kinetics10aWeisz-Prater criterion1 aBagwan, Farahanaz, M.1 aDadkar, Sarthak, S.1 aKinage, Anil, K.1 aVasireddy, Satyam, Naidu uhttps://library.ncl.res.in/content/reaction-kinetics-dehydrogenation-decahydroquinoline-quinoline-hydrogen-generation