02025nas a2200241 4500008004100000022001400041245011900055210006900174260010600243300001400349490000700363520106900370653002401439653003401463653003301497653002501530653001401555100002301569700002101592700001701613700002201630856013101652 2010 eng d a0277-538700aEfficient heterogeneous catalytic system for chemoselective hydrogenation of unsaturated ketones in aqueous medium0 aEfficient heterogeneous catalytic system for chemoselective hydr aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcNOV a3262-32680 v293 a

A highly chemoselective and green heterogeneous catalytic system of immobilized Ru(II)-phenanthroline complexes on amino functionalised MCM-41 material for the chemoselective hydrogenation of unsaturated ketones to unsaturated alcohols is demonstrated using water as a solvent The XRD and FTIR spectra show the highly ordered hexagonal nature of the MCM-41 even after encapsulation of the ruthenium complex The complex retains its configuration after anchoring as was confirmed by FTIR and UV-Vis analysis The detailed reaction parametric effect was studied for the hydrogenation of 3 methylpent-3-en-2-one to achieve complete conversion up to >99% chemoselectivity of 3-methylpent-3-en-2 ol The anchored heterogeneous catalysts were recycled effectively and reused five times with marginal changes in activity and selectivity The use of water as a solvent not only afforded high activity for the hydroge nation reaction compared to organic solvents but also afforded a green process Crown Copyright (C) 2010 Published by Elsevier Ltd All rights reserved

10a1 10 Phenanthroline10aalpha beta Unsaturated ketone10aChemoselective hydrogenation10amesoporous materials10aruthenium1 aDeshmukh, Amit, A.1 aKinage, Anil, K.1 aKumar, Rajiv1 aMeijboom, Reinout uhttps://library.ncl.res.in/content/efficient-heterogeneous-catalytic-system-chemoselective-hydrogenation-unsaturated-ketones-001897nas a2200241 4500008004100000022001400041245011900055210006900174260009200243300001000335490000600345520098600351653002501337653002301362653002401385653001501409653001201424100002201436700002101458700002501479700002101504856013001525 2012 eng d a1751-825300aEnvironmentally benign synthesis of beta-hydroxy sulfides using cyclic carbonates catalyzed by large-pore zeolites0 aEnvironmentally benign synthesis of betahydroxy sulfides using c a4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLANDbTAYLOR & FRANCIS LTDcAUG a19-260 v53 a

An efficient one-pot synthesis of beta-hydroxy sulfides from thiophenol and cyclic carbonates catalyzed by large-pore zeolites has been reported. Reaction of thiophenol with ethylene carbonate in the presence of the Na-X zeolite catalyst gave the highest yield of 2-(phenylthio)ethanol (100%), while reaction with propylene carbonate a highest yield of regioselective product 1-(phenylthio)propan-2-ol was obtained (97%). Enantiomerically pure 1,2-propylene carbonate gave highly regioselective and stereospecific phenylthiopropanol, demonstrating that original chirality of propylene carbonate is retained. A plausible mechanism has been proposed for zeolite-catalyzed transformation involving a chemoselective nucleophilic attack of thiophenoloxide ion onto the less-substituted carbon of cyclic carbonate. The Na-X zeolite catalyst is recyclable and provides advantages of green chemistry approach to the synthesis of beta-hydroxy sulfides without the use of any solvent.

10abeta-hydroxy sulfide10aethylene carbonate10apropylene carbonate10athiophenol10azeolite1 aUpare, Pravin, P.1 aKinage, Anil, K.1 aShingote, Savita, K.1 aGupte, Sunil, P. uhttps://library.ncl.res.in/content/environmentally-benign-synthesis-beta-hydroxy-sulfides-using-cyclic-carbonates-catalyzed-001901nas a2200265 4500008004100000022001400041245014500055210007200200260000800272300001500280490000700295520084600302653003301148653004301181653004701224653002201271653004001293653002901333100002901362700003001391700002301421700002801444700002101472856014201493 2025 eng d a2365-654900aEfficient synthesis of 3,3′-Spirooxindole γ-Butyrolactone via Rongalite-mediated domino reductive aldol and spiro-lactonization reactions0 aEfficient synthesis of 33′Spirooxindole γButyrolactone via Ronga cFEB ae2024059960 v103 a

In this study, we develop a novel methodology involving rongalite-mediated domino reductive/aldol reaction, followed by spiro-lactonization of 2-oxoindolin-3-ylidene acetates/malonates in presence of base to synthesis of 3,3 `-spirooxindole gamma-butyrolactone. The detail study, such as effect of solvent, effect of different base and substrate has been carried out. Scale up of this methodology is also done. Sodium hydroxymethanesulfinate dihydrate (rongalite) concurrently has a dual role in this context; it acts as a reducing agent as well as C1 synthon. This approach offers several advantages, such as being metal- and catalyst-free, involving a simple reaction protocol, having a wide substrate scope, using water as a green solvent, and providing good to excellent yields of the products under mild reaction conditions.

10a(+/-) Coixspirolactam A & [310a3 `-spirooxindole gamma-butyrolactone]10aDomino reductive/aldol/spiro-lactonization10aGood step economy10aRongalite as reductant & C1 synthon10aWater as a green solvent1 aChaudhari, Suryakant, S.1 aNichinde, Chandrakant, B.1 aPatil, Baliram, R.1 aGirase, Amardipsing, S.1 aKinage, Anil, K. uhttps://library.ncl.res.in/content/efficient-synthesis-33%E2%80%B2-spirooxindole-%CE%B3-butyrolactone-rongalite-mediated-domino-reductive02758nas a2200145 4500008004100000245015200041210006900193260000800262490000700270520213700277100002102414700002102435700002902456856012702485 2025 eng d00aEvaluation of reaction kinetics for chemoselective hydrogenation of citral for intensification of citral intermediates using copper-based catalysts0 aEvaluation of reaction kinetics for chemoselective hydrogenation cMAR0 v673 a

Citral intermediates’ formation kinetics is studied using non-noble metal catalyst (Cu/SiO2) to evaluate catalyst performance characteristics via chemoselective hydrogenation of citral. The catalyst is synthesised by the precipitation method and characterised using XRD, FESEM and BET surface area analyser. Hydrogenation experiments are carried out using an Autoclave reactor in the temperature range of 80–120°C, pressure range of 10–50 bar and for catalyst loadings of 0.5, 1 and 1.5 g. The intermediates product distribution comprises aldehyde and alcohol formation such as citronellal, nerol and citronellol formation. The performance of the Cu/SiO2 catalyst is evaluated using the parameters such as citral conversion, citronellol selectivity and yield as 96.96%, 95.30% and 92.30%, respectively under optimal conditions of 50 bar, 120°C and 1 g catalyst for the reaction time of 100 min. The absence of internal and external mass transfer limitations is verified using the Carberry number and Weisz-Prater modulus criterion. The intrinsic kinetics of the gas–liquid phase hydrogenation of citral is determined using the Langmuir–Hinshelwood-Hougen-Watson (LHHW) model for citral intermediates formation. The reaction kinetic parameters show that citronellol formation favours by the nerol route compared to citronellal conversion.

1 aDebtirtha, Banik1 aKinage, Anil, K.1 aVasireddy, Satyam, Naidu uhttps://library.ncl.res.in/content/evaluation-reaction-kinetics-chemoselective-hydrogenation-citral-intensification-citral