01552nas a2200205 4500008004100000022001400041245010000055210006900155260007300224300001200297490000800309520076700317653002301084653001701107653001801124653002401142100002801166700002901194856012301223 2008 eng d a0920-586100aPdCl2(bipy) complex - an efficient catalyst for Heck reaction in glycol-organic biphasic medium0 aPdCl2bipy complex an efficient catalyst for Heck reaction in gly aPO BOX 211, 1000 AE AMSTERDAM, NETHERLANDSbELSEVIER SCIENCE BVcFEB a353-3590 v1313 a

The Palladium complex PdCl2(bipy) (1) was found to be efficient in catalyzing the Heck reaction of aryl halides in a biphasic system comprising ethylene glycol along with an organic solvent. A proper tailoring of the organic phase ensured that the leaching of the catalyst to the organic phase was negligible. The catalyst was active for the Heck reaction of a number of olefins, aryl halides, in presence of organic and inorganic bases. The PdCl2(bipy) catalyst was stable and could be recycled for five times without any loss in activity and selectivity. A major advantage of this work is that unlike hitherto reported biphasic systems; it does not employ a water-soluble ligand to achieve biphasic catalysis. (c) 2007 Elsevier B.V. All rights reserved.

10aBiphasic catalysis10aC-C coupling10aHeck reaction10aPdCl2(bipy) complex1 aJagtap, Sangeeta, Vijay1 aDeshpande, Raj, Madhukar uhttps://library.ncl.res.in/content/pdcl2bipy-complex-efficient-catalyst-heck-reaction-glycol-organic-biphasic-medium-002196nas a2200265 4500008004100000022001400041245009500055210006900150260007300219300001000292490000800302520124600310653001001556653002301566653001801589653000901607653003701616100002501653700002101678700002101699700002601720700002901746700002901775856012601804 2011 eng d a1381-116900aOxidative carbonylation of amine using water-soluble palladium catalysts in biphasic media0 aOxidative carbonylation of amine using watersoluble palladium ca aPO BOX 211, 1000 AE AMSTERDAM, NETHERLANDSbELSEVIER SCIENCE BVcJAN a20-280 v3343 a

Application of water-soluble palladium catalysts for oxidative carbonylation of aniline to N,N' diphenyl urea (DPU) has been reported. The water-soluble palladium catalysts prepared from sulfonated N-containing ligands were found to be highly stable under reaction conditions and easily recyclable due to insoluble urea product in the reaction medium. This is in contrast to the sulfonated phosphine ligands, which are vulnerable to oxidation under reaction conditions, showing poor activity and stability. Commercially available as well as laboratory synthesized ligands were used for preparing water-soluble palladium catalysts, for oxidative carbonylation of aniline. The best activity was obtained for Pd complex with disodium 2,2'-bipyridine-4,4'-disulfonate (Bipy-DS) ligand. Under optimized conditions Pd(BipyDS)Pd(OAc)(2) catalyst gave TOF of similar to 210h(-1) with aniline conversion of similar to 97% with similar to 91% selectivity for N.N'-diphenyl urea. It was found that the catalyst was easily reusable up to five times, with negligible loss in the catalytic activity. The effect of reaction parameters was investigated and a plausible reaction mechanism has been proposed. (C) 2010 Elsevier B.V. All rights reserved.

10aAmine10aBiphasic catalysis10aCarbonylation10aUrea10aWater-soluble palladium catalyst1 aDidgikar, Mahesh, R.1 aJoshi, Sunil, S.1 aGupte, Sunil, P.1 aDiwakar, Makarand, M.1 aDeshpande, Raj, Madhukar1 aChaudhari, Raghunath, V. uhttps://library.ncl.res.in/content/oxidative-carbonylation-amine-using-water-soluble-palladium-catalysts-biphasic-media-001806nas a2200205 4500008004100000022001400041245007700055210006900132260007400201300001200275490000800287520106600295653002301361653001801384653001301402653002401415100002801439700002901467856010401496 2012 eng d a1878-519000aKinetics of the Heck reaction in biphasic organic-ethylene glycol medium0 aKinetics of the Heck reaction in biphasic organicethylene glycol aVAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDSbSPRINGERcAUG a457-4730 v1063 a

PdCl2(bipy) was found to be an efficient and stable catalyst in biphasic medium (organic-glycol) for the Heck reaction. The kinetics of the Heck coupling of styrene with iodobenzene using the same catalyst was studied in a biphasic medium in a temperature range of 393-413 K. The rate was found to have a first order dependence tending to a fractional order, on the iodobenzene as well as catalyst concentration. The rate was found to have a complex dependence on the styrene concentration and passes through a maximum, showing typical substrate inhibition kinetics. The rate had a first order dependence on the base (morpholine) concentration. The trends observed for the influence of the different parameters on the activity of the catalyst are in agreement with the established mechanism for Heck reaction. An empirical rate model has been proposed to fit the observed rate data. The activation energy was found to be 72.91 kJ/mol. This is the first time that kinetic modeling of Heck reaction in a biphasic medium (organic-glycol) has been attempted.

10aBiphasic catalysis10aHeck reaction10akinetics10aPdCl2(bipy) complex1 aJagtap, Sangeeta, Vijay1 aDeshpande, Raj, Madhukar uhttps://library.ncl.res.in/content/kinetics-heck-reaction-biphasic-organic-ethylene-glycol-medium-0