01955nas a2200241   4500008004100000022001400041245019800055210006900253260007300322300001200395490000800407520098500415653001401400653001401414653001901428653001801447653002201465100002001487700001901507700002501526700003001551856013201581       2012                        eng d  a0927-775700aGold nanoparticle embedded hydrogel matrices as catalysts: better dispersibility of nanoparticles in the gel matrix upon addition of N-bromosuccinimide leading to increased catalytic efficiency0 aGold nanoparticle embedded hydrogel matrices as catalysts better  aPO BOX 211, 1000 AE AMSTERDAM, NETHERLANDSbELSEVIER SCIENCE BVcNOV  a296-3010 v4143 a<p>A simple and convenient method for generating and immobilizing gold NPs into polyethylene glycol-polyurethane (PEGPU) matrices is presented. The gold NP immobilized PEGPU (Au NP-PEGPU) hydrogel matrices are easy to handle and can be used as catalysts. The efficiency, reusability and durability of the Au NP-PEGPU catalyst matrices were investigated using the reduction of 4-nitroaniline (4NA) to p-phenylenediamine (p-PDA) by sodium borohydride in the presence of the catalyst as a test reaction. The Au NPs in the PEGPU matrix got aggregated after 3 cycles of catalysis but dispersion could be regenerated by the addition of N-bromosuccinimide (NBS). After this regeneration process the Au NPs-PEGPU matrix showed excellent efficiency without any aggregation, leaching or degradation. The reusability of the catalyst for 28 cycles yielding a total turnover number of 3220 and turn over frequency of 0.152 s(-1) is demonstrated. (C) 2012 Elsevier B.V. All rights reserved.</p>10acatalysis10ahydrogels10aImmobilization10aNanoparticles10aTurn over numbers1 aRamtenki, Vilas1 aAnumon, V., D.1 aBadiger, Manohar, V.1 aPrasad, Bhagavatula L. V.  uhttps://library.ncl.res.in/content/gold-nanoparticle-embedded-hydrogel-matrices-catalysts-better-dispersibility-nanoparticles-001477nas a2200193   4500008004100000022001400041245011500055210006900170260011000239300001400349490000700363520068500370100002001055700001301075700002101088700001901109700003001128856012501158       2013                        eng d  a1144-054600aSynthesis of Ag-glyconanoparticles using C-glycosides, their lectin binding studies and antibacterial activity0 aSynthesis of Agglyconanoparticles using Cglycosides their lectin  aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcAUG  a3716-37200 v373 a<p>Two 12-C-glycosyl dodecanoic acids, namely, 1-(alpha-D-mannopyranosyl)-12-dodecanoic acid and 1-(alpha-D-glucopyranosyl)-12-dodecanoic acid were synthesized. Their ability to act as reducing and capping agents for the synthesis of water re-dispersible silver nanoparticles is displayed. These Ag C-glycosyl nanoparticles were later utilized to investigate the carbohydrate-lectin interactions. Furthermore, the specificity of mannoside binding to the surface of the Gram negative bacterium Escherichia coli has been utilized to demonstrate the enhanced antibacterial activity of Ag-C-mannosyl nanoparticles towards this bacterium as compared to Ag-C-glycosyl nanoparticles.</p>1 aRamtenki, Vilas1 aRaju, D.1 aMehta, Urmil, J.1 aRamana, C., V.1 aPrasad, Bhagavatula L. V.  uhttps://library.ncl.res.in/content/synthesis-ag-glyconanoparticles-using-c-glycosides-their-lectin-binding-studies-and-002265nas a2200253   4500008004100000022001400041245009000055210007000145260000900215300000700224490000800231520140700239653001601646653001901662653003001681653003601711653002001747100002601767700002001793700003001813700002201843700002001865856012601885       2025                        eng d  a0974-362600aDesign and synthesis of C-α-D-mannopyranoside linked mesoporous silica nanoparticles0 aDesign and synthesis of CαDmannopyranoside linked mesoporous sil  cMAR   a210 v1373 a<p>
	Mannose functionalized mesoporous silica nanoparticles (MSNs) offer a promising approach for developing more targeted, effective, and safer cancer therapies. For many of the applications, immobilization of carbohydrates like mannose onto MSNs is a crucial aspect, and in most cases, mannose moieties are connected through O-glycosidic linkages that are susceptible to acidic/enzymatic hydrolysis. To generate a stable mannose-functionalized MSN, we designed a novel C(14)-alpha-mannosylated tetradeca-1-yne. The key steps involved in the synthesis of C-mannosylated alkyne are C1-alkynylation of tri-O-acetyl-D-glucal with 1-trimethylsilyl-tetradec-1-yne, followed by stereoselective dihydroxylation and the isomerization of the internal triple bond to a terminal position. This mannose ligand was then immobilized onto azidopropyl-functionalized SBA-15 through the Cu(I)-catalyzed azide-alkyne click (CuAAC) reaction. Various physical techniques such as low-angle powder XRD, N-2 adsorption isotherms (BET), Fourier transform infrared (FTIR), high-resolution transmission electron microscopy (HRTEM), field emission scanning electron microscopy (FE-SEM), and thermogravimetric analysis (TGA) have been employed to characterize this C-mannosyl SBA-15 silica matrix. We evaluated the binding ability of C-mannosyl SBA-15 nanoparticles by using fluorescein-labelled Con-A as a target protein.</p>
10aC-mannoside10aClick reaction10amannose specific proteins10aMesoporous silica nanoparticles10aZipper reaction1 aNechooli, Hemanth, K.1 aRamtenki, Vilas1 aKumar, Chepuri, V. Suneel1 aPrasad, V., B. L.1 aRamana, Chepuri  uhttps://library.ncl.res.in/content/design-and-synthesis-c-%CE%B1-d-mannopyranoside-linked-mesoporous-silica-nanoparticles