02041nas a2200301   4500008004100000022001400041245009000055210006900145260010600214300001400320490000700334520096800341653002401309653001601333653001401349100002501363700003101388700002401419700002801443700001601471700001601487700001701503700002301520700002401543700002401567700002601591856012201617       2011                        eng d  a0960-894X00aNovel hybrids of fluconazole and furanones: design, synthesis and antifungal activity0 aNovel hybrids of fluconazole and furanones design synthesis and   aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcAUG  a4873-48780 v213 a<p>During our efforts to develop new antifungal agents, a number of hybrid molecules containing furanones and fluconazole pharmacophores were designed and synthesized. The new chemical entities thus synthesized were tested for their potential as antifungal agents against various fungal strains and it was observed that the compounds with general structure 7 were potent inhibitors of Candida albicans ATCC 24433, Candida glabrata ATCC 90030, Candida tropicalis ATCC 750 and Candida neoformans ATCC 34664 while the fluconazole analogues 12 exhibited antifungal activity against Candida albicans ATCC 24433 and Candida glabrata ATCC 90030. The structure-activity relationship for these compounds is discussed. The synthetic strategies used in the present work have potential to prepare a large number of compounds for further refinement of structures to obtain molecules suitable for development as antifungal drugs. (C) 2011 Elsevier Ltd. All rights reserved.</p>10aAntifungal activity10aFluconazole10aFuranones1 aBorate, Hanumant, B.1 aSawargave, Sangmeshwer, P.1 aChavan, Subhash, P.1 aChandavarkar, Mohan, A.1 aIyer, Ramki1 aTawte, Amit1 aRao, Deepali1 aDeore, Jaydeep, V.1 aKudale, Ananada, S.1 aMahajan, Pankaj, S.1 aKangire, Gopinath, S.  uhttps://library.ncl.res.in/content/novel-hybrids-fluconazole-and-furanones-design-synthesis-and-antifungal-activity-001626nas a2200265   4500008004100000022001400041245016100055210006900216260010600285300001400391490000700405520058200412653001400994653002001008653001201028653001801040100003101058700002401089700002301113700002601136700002401162700002401186700002501210856012501235       2011                        eng d  a0040-403900aOne-step synthesis of 4-alkyl-3-aryl-2,6-dicyanoanilines and their use in the synthesis of highly functionalized 2,3,5,6,7-and 2,3,4,5,7-substituted indoles0 aOnestep synthesis of 4alkyl3aryl26dicyanoanilines and their use   aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcOCT  a5491-54930 v523 a<p>A three-component, one-step method for the synthesis of 4-alkyl-3-aryl-2,6-dicyanoanilines involving reaction of alkyl aldehyde, malononitrile and aryl aldehyde in presence of morpholine is reported. Highly functionalized 2,3,5,6,7- and 2,3,4,5,7-substituted indoles were prepared from these dicyanoanilines by reaction with ethyl bromoacetate. These substituted dicyanoanilines and indoles have a potential to be converted into various other compounds taking advantage of various functional groups present in these molecules. (C) 2011 Elsevier Ltd. All rights reserved.</p>10aaldehydes10aDicyanoanilines10aindoles10aMalononitrile1 aSawargave, Sangmeshwer, P.1 aKudale, Ananada, S.1 aDeore, Jaydeep, V.1 aBhosale, Dattatry, S.1 aDivse, Jaisingh, M.1 aChavan, Subhash, P.1 aBorate, Hanumant, B.  uhttps://library.ncl.res.in/content/one-step-synthesis-4-alkyl-3-aryl-26-dicyanoanilines-and-their-use-synthesis-highly-000652nas a2200157   4500008004100000022001400041245008100055210006900136260008600205300001200291490000700303100002500310700002400335700002400359856011100383       2012                        eng d  a0030-494800aSynthesis of substituted 2,6-dicyanoanilines and related compounds. a review0 aSynthesis of substituted 26dicyanoanilines and related compounds  a325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USAbTAYLOR & FRANCIS INCcJAN  a467-5210 v441 aBorate, Hanumant, B.1 aKudale, Ananada, S.1 aAgalave, Sandip, G.  uhttps://library.ncl.res.in/content/synthesis-substituted-26-dicyanoanilines-and-related-compounds-review-001437nas a2200277   4500008004100000022001400041245009800055210006900153260010600222300001400328490000700342520042300349653002300772653002200795653001600817653001900833653001800852100002500870700002500895700002400920700002400944700002700968700002200995700002301017856011901040       2013                        eng d  a0040-403900aOne-step method for the synthesis of aryl olefins from aryl aldehydes and aliphatic aldehydes0 aOnestep method for the synthesis of aryl olefins from aryl aldeh  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcMAR  a1528-15300 v543 a<p>A conceptually new one-step reaction affording unexpected aryl olefinic product from aromatic aldehyde, aliphatic aldehyde and malononitrile in the presence of acetic acid-ammonium acetate under mild reaction conditions without using any metal catalyst is reported. This novel reaction was used to prepare a number of substituted aryl olefins including new molecules. (c) 2013 Elsevier Ltd. All rights reserved.</p>10aAliphatic aldehyde10aAromatic aldehyde10aAryl olefin10aDicyanoaniline10aMalononitrile1 aBorate, Hanumant, B.1 aGaikwad, Supriya, H.1 aKudale, Ananada, S.1 aChavan, Subhash, P.1 aPharande, Shrikant, G.1 aWagh, Vitthal, D.1 aSawant, Vikram, S.  uhttps://library.ncl.res.in/content/one-step-method-synthesis-aryl-olefins-aryl-aldehydes-and-aliphatic-aldehydes-001673nas a2200193   4500008004100000245012600041210006900167260000800236490000700244520094400251100002401195700002401219700001901243700002201262700002201284700002401306700002301330856012601353       2019                        eng d00aSynthesis of biphasic nanomaterials based on ZnO and SnO2: application towards photocatalytic degradation of acid red dye0 aSynthesis of biphasic nanomaterials based on ZnO and SnO2 applic  cAPR0 v183 aZn2SnO4/SnO2 and ZnO/SnO2 biphasic nanocatalysts have been synthesized by a facile solvothermal method using ethylene glycol (EG) as solvent in three different ways maintaining the pH of the solution at either 3 or 9 followed by calcination at 700 °C. The nanocatalysts are characterized by different techniques to investigate their structure, composition, morphology and optical properties. The XRD results indicate the formation of pristine biphasic composites. The UV-absorbance and photoluminescence spectra confirms the formation of biphasic composites as well as presence of large number of defects in the prepared nanocatalysts. The biphasic nanocomposites possess better photocatalytic activity towards the degradation of Acid Red-183 (AR-183) dye than pristine SnO2 and ZnO nanoparticles. This is mainly due to better charge separation, minimal recombination rate of charge carriers and defect-riched structures of nanocatalysts.1 aKudale, Ananada, S.1 aKamble, Santosh, B.1 aGore, Anil, H.1 aPisal, Mahesh, M.1 aSalokhe, Anil, T.1 aKolekar, Govind, B.1 aHelavi, Vasant, B.  uhttps://library.ncl.res.in/content/synthesis-biphasic-nanomaterials-based-zno-and-sno2-application-towards-photocatalytic