02058nas a2200241   4500008004100000022001400041245011200055210006900167260008100236300000600317490000600323520117100329100002101500700001901521700002301540700002201563700002101585700001901606700002201625700001901647700002001666856013001686       2013                        eng d  a1757-474900aDraft genome of ochrobactrum intermedium strain M86 isolated from non-ulcer dyspeptic individual from India0 aDraft genome of ochrobactrum intermedium strain M86 isolated fro  a236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLANDbBIOMED CENTRAL LTDcAPR  a70 v53 a<p>Background: Ochrobactrum intermedium is an emerging opportunistic pathogen of humans that is closely related to members of the genus Brucella. Earlier, we reported the case of an Indian subject with non-ulcer dyspeptic symptoms whose urease positive gastric biopsy revealed the presence of Helicobacter pylori along with non-Helicobacter like bacteria, eventually cultured and identified as O. intermedium strain M86. Results: Here, we describe the unclosed draft genome of the strain M86 with a length of 5,188,688 bp and mean G+C content of 57.9%. We have also identified many putative gene clusters that might be responsible for its persistence in the gastric mucosa. Comparative analysis of genomic features of Ochrobactrum intermedium strain M86 and Ochrobactrum intermedium LMG 3301(T) was also done. Conclusions: This paper attempts to gain whole-genome based insights into the putative gene determinants of O. intermedium for survival in the highly acidic stomach lumen environment. Identification of genes putatively involved in the various metabolic pathways may lead to a better understanding of the survival of O. intermdedium in acidic condition.</p>1 aKulkarni, Girish1 aDhotre, Dhiraj1 aDharne, Mahesh, S.1 aShetty, Sudarshan1 aChowdhury, Somak1 aMisra, Vatsala1 aMisra, Sriprakash1 aPatole, Milind1 aShouche, Yogesh  uhttps://library.ncl.res.in/content/draft-genome-ochrobactrum-intermedium-strain-m86-isolated-non-ulcer-dyspeptic-individual-0