01396nas a2200229   4500008004100000022001400041245025400055210006900309260007700378300001400455490000800469520037400477653001700851653002600868653002100894653003000915653002200945100001900967700003100986700001901017856013001036       2013                        eng d  a1615-415000aDesymmetrization approach to the enantiopure syn/anti-1,5-diols via hydrolytic kinetic resolution (hkr) of functionalized meso-bis-epoxides: further elaboration to syn/syn-1,3,5-triols and application to the formal synthesis of cryptocarya diacetate0 aDesymmetrization approach to the enantiopure synanti15diols via   aBOSCHSTRASSE 12, D-69469 WEINHEIM, GERMANYbWILEY-V C H VERLAG GMBHcJUN  a1719-17230 v3553 a<p>A new approach has been developed for the synthesis of enantiopure syn/anti-1,5-diols by desymmetrization of functionalized meso-bis-epoxides using hydrolytic kinetic resolution (HKR). The usage of this protocol was demonstrated by converting syn-1,5-diols into syn/syn-1,3,5-triols and its subseqent application to the formal synthesis of cryptocarya diacetate.</p>10abis-epoxides10acryptocarya diacetate10adesymmetrization10astereoselective reduction10asynthetic methods1 aKumar, Pradeep1 aChowdhury, Partha, Sarathi1 aPandey, Menaka  uhttps://library.ncl.res.in/content/desymmetrization-approach-enantiopure-synanti-15-diols-hydrolytic-kinetic-resolution-hkr-001177nas a2200229   4500008004100000022001400041245010100055210006900156260007700225300001400302490000900316520034500325653001300670653001500683653001200698653002200710653002000732653002100752100003100773700001900804856012400823       2013                        eng d  a1434-193X00aTotal synthesis of umuravumbolide and hyptolide through silicon-tethered ring-closing metathesis0 aTotal synthesis of umuravumbolide and hyptolide through silicont  aBOSCHSTRASSE 12, D-69469 WEINHEIM, GERMANYbWILEY-V C H VERLAG GMBHcJUL  a4586-45930 v20133 a<p>The total synthesis of umuravumbolide and hyptolide has been achieved in a efficient manner by using temporary silicon-tethered ring-closing metathesis and cross-coupling reactions as key steps. The stereogenic centres were generated by means of proline-catalysed -aminoxylation of aldehydes and Brown's asymmetric allylation method.</p>10alactones10aMetathesis10aSilanes10asynthetic methods10aTotal synthesis10aWittig reactions1 aChowdhury, Partha, Sarathi1 aKumar, Pradeep  uhttps://library.ncl.res.in/content/total-synthesis-umuravumbolide-and-hyptolide-through-silicon-tethered-ring-closing-0