01866nas a2200229 4500008004100000022001400041245011100055210006900166260007300235300001400308490000700322520103200329653000901361653001001370653002301380653001801403100002201421700002101443700002001464700002101484856013101505 2011 eng d a0167-577X00aNovel route for rapid biosynthesis of lead nanoparticles using aqueous extract of Jatropha curcas L. latex0 aNovel route for rapid biosynthesis of lead nanoparticles using a aPO BOX 211, 1000 AE AMSTERDAM, NETHERLANDSbELSEVIER SCIENCE BVcOCT a3170-31720 v653 a

We are reporting a novel, low-cost and eco-friendly route for rapid synthesis of lead nanoparticles by using 0.5% aqueous extract of Jatropha curcas L latex. Lead nanoparticles were characterized initially by UV-vis spectroscopy and shown distinct peak at 218 nm. This peak was highly specific for lead nanoparticles. Formation of Pb (0) was confirmed by X-ray diffraction technique (XRD).Transmission electron microscopy (TEM) was performed for estimating the size and shape of nanoparticles. The average size of lead nanoparticles was found to be in the range of 10 to 12.5 nm. Energy dispersive analysis of X-rays (EDAX) showed distinct peaks of lead. Fourier Transform Infrared Spectroscopy (FTIR) were performed to find the role of cyclic peptides namely curcacycline A (an octapeptide) and curcacycline B (a nonapeptide) as a possible reducing and capping agents present in the latex of Jatropha curcas L. Lead nanoparticles formed by the above method were monodisperse. (C) 2011 Elsevier B.V. All rights reserved.

10aFTIR10aLatex10aLead nanoparticles10aNanoparticles1 aJoglekar, Shriram1 aKodam, Kisan, M.1 aDhaygude, Mayur1 aHudlikar, Manish uhttps://library.ncl.res.in/content/novel-route-rapid-biosynthesis-lead-nanoparticles-using-aqueous-extract-jatropha-curcas-l-001845nas a2200229 4500008004100000022001400041245009500055210006900150260007300219300001200292490000700304520098700311653001701298653002401315653005101339653001901390100002101409700002201430700002001452700002101472856012201493 2012 eng d a0167-577X00aGreen synthesis of TiO2 nanoparticles by using aqueous extract of Jatropha curcas L. latex0 aGreen synthesis of TiO2 nanoparticles by using aqueous extract o aPO BOX 211, 1000 AE AMSTERDAM, NETHERLANDSbELSEVIER SCIENCE BVcMAY a196-1990 v753 a

Present study deals with a green synthesis of TiO2 nanoparticles by using 0.3% aqueous extract prepared from latex of Jatropha curcas L. TiO2 nanoparticles were characterized by X-ray diffraction (XRD), Selected Area Electron Diffraction (SAED), Transmission Electron Microscopy (TEM), Energy Dispersive Analysis of X-rays (EDAX) and Fourier Transform Infrared Spectroscopy (FTIR). Fourier Transform Infrared Spectroscopy (FTIR) were performed to find the role of curcain (enzyme), cyclic peptides namely curcacycline A (an octapeptide) and curcacycline B (a nonapeptide) as a possible reducing and capping agents, present in the latex of J. curcas L. The average size of TiO2 nanoparticles was found to be in the range of 25 to 100 nm. Our result shows that there are two broad categories of nanoparticles, first having diameter from 25 to 50 nm which are mostly spherical in shape and second having some larger and uneven shapes. (C) 2012 Elsevier B.V. All rights reserved.

10aBiomaterials10aElectron microscopy10aFourier Transform Infrared Spectroscopy (FTIR)10aNanostructures1 aHudlikar, Manish1 aJoglekar, Shriram1 aDhaygude, Mayur1 aKodam, Kisan, M. uhttps://library.ncl.res.in/content/green-synthesis-tio2-nanoparticles-using-aqueous-extract-jatropha-curcas-l-latex-001742nas a2200217 4500008004100000022001400041245007600055210006900131260007400200300000800274490000700282520099000289653002001279653001001299653002201309100002101331700002201352700002001374700002101394856010901415 2012 eng d a1388-076400aLatex-mediated synthesis of ZnS nanoparticles: green synthesis approach0 aLatexmediated synthesis of ZnS nanoparticles green synthesis app aVAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDSbSPRINGERcMAY a8650 v143 a

A low-cost, green synthesis of ZnS nanoparticles is reported using 0.3 % latex solution prepared from Jatropha curcas L. ZnS nanoparticles were characterized by X-ray diffraction, selected area electron diffraction, transmission electron microscopy, energy dispersive analysis of X-rays, UV-vis optical absorption and photoluminescence techniques. Fourier Transform Infrared Spectroscopy was performed to find the role of cyclic peptides namely curcacycline A (an octapeptide), curcacycline B (a nonapeptide) and curcain (an enzyme) as a possible reducing and stabilizing agents present in the latex of J. curcas L. The average size of ZnS nanoparticles was found to be 10 nm. Latex of J. curcas L. itself acts as a source of sulphide (S-2) ions that are donated to Zn ions under present experimental conditions. Source of sulphide (S-2) ions is still unclear, but we speculate that cysteine or thiol residues present in enzyme curcain may be donating these sulphide (S-2) ions.

10agreen synthesis10aLatex10aZnS nanoparticles1 aHudlikar, Manish1 aJoglekar, Shriram1 aDhaygude, Mayur1 aKodam, Kisan, M. uhttps://library.ncl.res.in/content/latex-mediated-synthesis-zns-nanoparticles-green-synthesis-approach-002163nas a2200241 4500008004100000022001400041245009700055210006900152260006700221300001400288490000800302520131400310653002101624653001801645653001201663653000901675653002201684100001801706700002101724700002601745700002601771856012401797 2012 eng d a1438-769700aLipase-mediated hydrolysis of flax seed oil for selective enrichment of alpha-linolenic acid0 aLipasemediated hydrolysis of flax seed oil for selective enrichm a111 RIVER ST, HOBOKEN 07030-5774, NJ USAbWILEY-BLACKWELLcNOV a1246-12530 v1143 a

Polyunsaturated fatty acids (PUFA) are important ingredients of human diet because of their prominent role in the function of human brain, eye and kidney. alpha-Linolenic acid (ALA), a C18, n-3 PUFA is a precursor of long chain PUFA in humans. Commercial lipases of Candida rugosa, Pseudomonas cepacea, Pseudomonas fluorescens, and Rhizomucor miehei were used for hydrolysis of flax seed oil. Reversed phase high performance liquid chromatography followed by gas chromatography showed that the purified oil contained 12 triacylglycerols (TAGs) with differences in fatty acid compositions. Flax seed oil TAGs contained alpha-linolenic acid (50%) as a major fatty acid while palmitic, oleic, linoleic made up rest of the portion. Among the four commercial lipases C. rugosa has preference for ALA, and that ALA was enriched in free fatty acids. C. rugosa lipase mediated hydrolysis of the TAGs resulted in a fatty acid mixture that was enriched in alpha-linolenic to about 72% yield that could be further enriched to 80% yield by selective removal of saturated fatty acids by urea complexation. Such purified ALA can be used for preparation of ALA-enriched glycerides. Practical applications: This methodology allows purifying ALA from fatty acid mixture obtained from flax seed oil by urea complexation.

10aa-Linolenic acid10aFlax seed oil10aLipases10aPUFA10aUrea complexation1 aRupani, Banin1 aKodam, Kisan, M.1 aGadre, Ramchandra, V.1 aNajafpour, Ghasem, D. uhttps://library.ncl.res.in/content/lipase-mediated-hydrolysis-flax-seed-oil-selective-enrichment-alpha-linolenic-acid-002318nas a2200277 4500008004100000022001400041245015400055210006900209260007300278300001200351490000700363520129900370653001801669653002501687653000901712653001001721653001601731653003801747100002001785700002501805700002001830700002201850700002101872700002101893856012601914 2012 eng d a0927-776500aNovel route for rapid biosynthesis of copper nanoparticles using aqueous extract of Calotropis procera L. latex and their cytotoxicity on tumor cells0 aNovel route for rapid biosynthesis of copper nanoparticles using aPO BOX 211, 1000 AE AMSTERDAM, NETHERLANDSbELSEVIER SCIENCE BVcJUN a284-2880 v953 a

This paper accounts for novel, low-cost, eco-friendly route for rapid biosynthesis of copper nanoparticles. Cysteine proteases present in the latex of Calotropis procera L. were used to fabricate copper nanoparticles from copper acetate. Copper nanoparticles were initially characterized by transmission electron microscopy (TEM) and X-ray diffraction technique (XRD). Transmission electron microscopy (TEM) was used to estimate the size and shape of nanoparticles. The average size of copper nanoparticles was found to be 15 +/- 1.7 nm. Energy dispersive analysis of X-rays (EDAX) showed distinct peaks of copper. Fourier transform infrared spectroscopy (FTIR) was performed to confirm capping behavior of the latex proteins that contributed to long term stability of copper nanoparticles (6 months) in aqueous medium. Copper nanoparticles synthesized by above method were monodisperse type. Cytotoxicity studies of latex stabilized copper nanoparticles were carried out on HeLa, A549 and BHK21 cell lines by MTT dye conversion assay. HeLa, A549 and BHK21 cells showed excellent viability even at 120 mu M concentration of copper nanoparticles. This shows that copper nanoparticles synthesized by above method hold excellent biocompatibility. (C) 2012 Elsevier B.V. All rights reserved.

10aBiocompatible10aCopper nanoparticles10aFTIR10aLatex10aTumor cells10aX-ray diffraction technique (XRD)1 aHarne, Shrikant1 aSharma, Ashwinikumar1 aDhaygude, Mayur1 aJoglekar, Shriram1 aKodam, Kisan, M.1 aHudlikar, Manish uhttps://library.ncl.res.in/content/novel-route-rapid-biosynthesis-copper-nanoparticles-using-aqueous-extract-calotropis-001799nas a2200229 4500008004100000022001400041245009000055210006900145260005700214300001200271490000700283520098800290100002401278700002401302700002001326700002101346700001601367700002401383700002601407700002101433856011501454 2013 eng d a0343-865100aAlishewanella solinquinati sp nov., isolated from soil contaminated with textile dyes0 aAlishewanella solinquinati sp nov isolated from soil contaminate a233 SPRING ST, NEW YORK, NY 10013 USAbSPRINGERcOCT a454-4590 v673 a

A novel Gram-negative, motile, rod-shaped, facultative anaerobic bacterial strain, KMK6(T), was isolated from soil contaminated with textile dyes from an industrial estate located at Ichalkaranji, Maharashtra, India, and its taxonomical position was established by using a polyphasic approach. The major cellular fatty acids included C-17:1 omega 8c, summed feature 3 (C-16:1 omega 7c and/or iso-C-15:0 2-OH), C-17:0, C-16:0,C- and C-18:1 omega 7c. The DNA G+C content of strain KMK6(T) was 48.8 mol %. 16S rRNA gene sequence analysis confirmed its placement in the genus Alishewanella, and exhibited sequence similarity levels of below 97 % to the type strains of validly published Alishewanella species. On the basis of genotypic and phenotypic evidence, strains KMK6(T) is considered to be a novel species of the genus Alishewanella, for which we propose that strain KMK6(T) (=NCIM 5295(T) =BCRC 17848(T)) is assigned to a novel species, Alishewanella solinquinati sp. nov.

1 aKolekar, Yogesh, M.1 aPawar, Shrikant, P.1 aAdav, Sunil, S.1 aZheng, Liu-Qiang1 aLi, Wen-Jun1 aShouche, Yogesh, S.1 aDastager, Syed, Gulam1 aKodam, Kisan, M. uhttps://library.ncl.res.in/content/alishewanella-solinquinati-sp-nov-isolated-soil-contaminated-textile-dyes-002071nas a2200181 4500008004100000245008400041210006900125260000800194300001200202490000800214520144300222100002201665700002401687700002601711700002001737700002101757856011101778 2016 eng d00aCharacterization of roseomonas and nocardioides spp. for arsenic transformation0 aCharacterization of roseomonas and nocardioides spp for arsenic  cNOV a742-7500 v3183 aThe metalloid arsenic predominantly exists in the arsenite [As(III)] and arsenate [As(V)]. These two forms are respectively oxidized and reduced by microbial redox processes. This study was designed to bioprospect arsenic tolerating bacteria from Lonar lake and to characterize their arsenic redoxing ability. Screening of sixty-nine bacterial species isolated from Lonar lake led to identification of three arsenic oxidizing and seven arsenic-reducing species. Arsenite oxidizing isolate Roseomonas sp. L-159a being closely related to Roseomonas cervicalis ATCC 49957 oxidized 2 mM As(III) in 60 h. Gene expression of large and small subunits of arsenite oxidase respectively showed 15- and 17-fold higher expression. Another isolate Nocardioides sp. L-37a formed a clade with Nocardioides ghangwensis JC2055, exhibited normal growth with different carbon sources and pH ranges. It reduced 2 mM As(V) in 36 h and showed constitutive expression of arsenate reductase which increased over 4-fold upon As(V) exposure. Genetic markers related to arsenic transformation were identified and characterized from the two isolates. Moderate resistance against the arsenicals was exhibited by the two isolates in the range of 1-5 mM for As(III) and 1-200 mM for As(V). Altogether we provide multiple evidences to indicate that Roseomonas sp. and Nocardioides sp. exhibited arsenic transformation ability. (C) 2016 Elsevier B.V. All rights reserved.1 aBagade, Aditi, V.1 aBachate, Sachin, P.1 aDholakia, Bhushan, B.1 aGiri, Ashok, P.1 aKodam, Kisan, M. uhttps://library.ncl.res.in/content/characterization-roseomonas-and-nocardioides-spp-arsenic-transformation01856nas a2200277 4500008004100000022001400041245017400055210006900229260007100298300001400369490000600383520075300389653004201142653004201184653001701226653002001243653002901263653001901292100002201311700002601333700002301359700002001382700002801402700002101430856012701451 2016 eng d a2168-048500aProblem solving and environmentally benign approach toward diversity oriented synthesis of novel 2-amino-3-phenyl (or Alkyl) sulfonyl-4H-chromenes at ambient temperature0 aProblem solving and environmentally benign approach toward diver a1155 16TH ST, NW, WASHINGTON, DC 20036 USAbAMER CHEMICAL SOCcJUN a3450-34640 v43 a

A problem solving, environmentally benign, and diversity oriented protocol has been described for multi component synthesis of medicinally privileged 2-amino-3-phenyl (or methyl) sulfonyl-4H-chromenes by one-pot, three component condensation among aldehydes, phenyl (or methyl) sulphonyl acetonitrile, and alpha-naphthol, 3-dimethylamino phenol, 4-hydroxy-N-methyl-quinoline-2-one as well as 4-hydroxycarbazole, using diethylamine as an efficient organo catalyst. The catalyst employed is commercially available, inexpensive, and nontoxic. Ambient reaction conditions, very high yields, wide scope, and avoidance of conventional isolation as well as chromatographic purification have improved the practical utility of this protocol manifold.

10a2-Amino-3-methylsulfonyl-4H-chromenes10a2-Amino-3-phenylsulfonyl-4H-chromenes10adiethylamine10agreen chemistry10aMulticomponent synthesis10aorganocatalyst1 aPandit, Kapil, S.1 aKupwade, Ravindra, V.1 aChavan, Pramod, V.1 aDesai, Uday, V.1 aWadgaonkar, Prakash, P.1 aKodam, Kisan, M. uhttps://library.ncl.res.in/content/problem-solving-and-environmentally-benign-approach-toward-diversity-oriented-synthesis01042nas a2200169 4500008004100000245010700041210006900148260000800217300001200225490000700237520041400244100002200658700002000680700002800700700002100728856012300749 2017 eng d00aSulfamic acid-catalyzed, environmentally benign synthesis of bis-tetronic acids at ambient temperature0 aSulfamic acidcatalyzed environmentally benign synthesis of biste cJAN a141-1520 v433 aAn enviro-economic protocol has been described for the synthesis of bis-tetronic acids by pseudo-three-component condensation between aldehydes/isatins and tetronic acid using sulfamic acid as a solid acid catalyst. Easy commercial availability of the catalyst at extremely low cost, excellent yields and avoidance of conventional purification procedures are the main merits of this energy efficient protocol.1 aPandit, Kapil, S.1 aDesai, Uday, V.1 aWadgaonkar, Prakash, P.1 aKodam, Kisan, M. uhttps://library.ncl.res.in/content/sulfamic-acid-catalyzed-environmentally-benign-synthesis-bis-tetronic-acids-ambient02531nas a2200325 4500008004100000022001400041245014900055210006900204260000800273300001200281490000700293520147400300653000601774653000601780653003801786653001501824653002001839653002001859653001701879653002801896653002901924100000501953700000501958700002801963700002301991700002102014700002002035700001902055856013102074 2019 eng d a0045-206800aClick chemistry based multicomponent approach in the synthesis of spirochromenocarbazole tethered 1,2,3-triazoles as potential anticancer agents0 aClick chemistry based multicomponent approach in the synthesis o cAPR a475-4860 v853 a

A series of spirochromenocarbazole tethered 1,2,3-triazoles were synthesized via click chemistry based one-pot, five component reaction between N-propargyl isatins, malononitrile, 4-hydroxycarbazole, aralkyl halides and sodium azide using cellulose supported CuI nanoparticles (Cell-CuI NPs) as the heterogeneous catalyst. Antiproliferative activity of all the synthesized compounds was investigated against panel of cancer cell lines such as MCF-7, MDA-MB-231, HeLa, PANG-1, A-549, and THP-1. Many of the synthesized compounds exhibited good anti-proliferative activity against breast (MCF-7 and MDA-MB-231) and cervical (HeLa) cancer cells with IC50 values less than 10 mu M. In case of MCF-7 cells, among the nine compounds that showed good anti-proliferative activity, compounds 6f and 6j were found to be highly potent (IC50 , = 2.13 mu M and 4.80 mu M, respectively). In case of MDA-MB-231, three compounds (6k, 6j and 6s) showed antiproliferative activity amongst which 6k was the most potent one (IC50 = 3.78 mu M). On the other hand, in cervical cancer HeLa cells, compounds 6b, 6g, 6s and 6u showed excellent antiproliferative activity (IC50 = 4.05, 3.54, 3.83, 3.35 mu M, respectively). All the compounds were found to be nontoxic to the human umbilical vein endothelial cells (HUVECs). AO and EtBr staining and fluorescence microscopy studies of the active compounds (IC50 < 5 mu M) suggested that these compounds induce cell death by apoptosis.

10a110a210a3-Triazolylspirochromenocarbazole10aAnticancer10aApoptotic assay10aClick chemistry10aCytotoxicity10aheterogeneous catalysis10aMulticomponent synthesis1 a1 a1 aWadgaonkar, Prakash, P.1 aTapase, Savita, R.1 aKodam, Kisan, M.1 aChoudhari, Amit1 aSarkar, Dhiman uhttps://library.ncl.res.in/content/click-chemistry-based-multicomponent-approach-synthesis-spirochromenocarbazole-tethered-123