02211nas a2200181 4500008004100000245012700041210006900168260000800237300001600245490000700261520153200268100002401800700001801824700002201842700002001864700001701884856012801901 2012 eng d00aTaco complex derived from a bis-crown ether capable of executing molecular logic operation through reversible complexation0 aTaco complex derived from a biscrown ether capable of executing  cJUL a6789–68000 v773 a

As learned from natural systems, self-assembly and self-sorting help in interconnecting different molecular logic gates and thus achieve high-level logic functions. In this context, demonstration of important logic operations using changes in optical responses due to the formation of molecular assemblies is even more desirable for the construction of a molecular computer. Synthesis of an appropriate divalent as well as a luminescent crown ether based host 1 and paraquat derivatives, 2(PF6)2 and 3(PF6)2, as guests helped in demonstrating a reversible [3](taco complex) (1·{2(PF6)2}2 or 1·{3(PF6)2}2) formation in nonpolar solvent. Detailed 1H NMR studies revealed that two paraquat units were bound cooperatively by the two crown units in 1. Because of preorganization, the flexible host molecule 1 adopts a folded conformation, where each of two paraquat units remain sandwiched between the two aromatic units of each folded crown ether moiety in 1. Disassembly of the “taco” complex in the presence of KPF6 and reassembly on subsequent addition of DB18C6 was initially demonstrated by 1H NMR spectral studies, which were subsequently corroborated through luminescence spectral studies. Further, luminescence spectral responses as output signals with appropriate and two independent molecular inputs could be correlated to demonstrate basic logic operation like OR and YES gates, while the results of the three molecular inputs could be utilized to demonstrate important logic operation like an INHIBIT gate.

1 aMandal, Amal, Kumar1 aDas, Priyadip1 aMahato, Prasenjit1 aAcharya, Suhash1 aDas, Amitava uhttps://library.ncl.res.in/content/taco-complex-derived-bis-crown-ether-capable-executing-molecular-logic-operation-through01122nas a2200193 4500008004100000022001400041245013800055210006900193260011000262300001400372490000700386520030900393100001900702700001500721700002300736700002500759700001700784856012700801 2015 eng d a1359-734500aTuning of multiple luminescence outputs and white-light emission from a single gelator molecule through an ESIPT coupled AIEE process0 aTuning of multiple luminescence outputs and whitelight emission  aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcDEC a2130-21330 v513 a

A unique example of an ESIPT coupled AIEE process, associated with a single molecule (1), is utilized for generating multiple luminescent colors (blue-green-white-yellow). The J-aggregated state of 1 forms a luminescent gel in THF and this luminescent property is retained even in the solid state.

1 aMaity, Arunava1 aAli, Firoj1 aAgarwalla, Hridesh1 aAnothumakkool, Bihag1 aDas, Amitava uhttps://library.ncl.res.in/content/tuning-multiple-luminescence-outputs-and-white-light-emission-single-gelator-molecule-002225nas a2200205 4500008004100000022001400041245012900055210006900184260007100253300001200324490000700336520140500343100002701748700002101775700001901796700002601815700003501841700001701876856012601893 2016 eng d a0022-326300aTuning emission responses of a triphenylamine derivative in host-guest complexes and an unusual dynamic inclusion phenomenon0 aTuning emission responses of a triphenylamine derivative in host a1155 16TH ST, NW, WASHINGTON, DC 20036 USAbAMER CHEMICAL SOCcJAN a512-5210 v813 a

A newly synthesized triphenylamine derivative (1Cl(3)) shows significant differences in inclusion complex formation with two different macrocyclic hosts, cucurbit[7]uril (CB[7]) and beta-cyclodextrin (beta-CD). Detailed investigations by NMR spectroscopy reveal that CB[7] forms a 1:3 host-guest complex ([1 center dot 3{CB[7]}]Cl-3) in which three arms of 1Cl(3) are bound to three host molecules. On the other hand, beta-CD forms a dynamic 1:1 inclusion complex ([1 center dot{beta-CD}]Cl-3) by binding to only one of the three arms of 1Cl(3) at a given time. The formation of a 1:1 host-guest complex with beta-CD and 1:3 host-guest complex with CB[7] was also confirmed from the results of the isothermal titration calorimetric studies. Interestingly, 1Cl(3) exhibits a rare dual emission property in solution at room temperature with the lower and higher energy bands arising from a locally excited state and an intramolecular charge-transfer transition, respectively. The difference in inclusion complex formation behavior of 1Cl(3) with the two macrocyclic hosts results in the stabilization of different emission states in the two inclusion complexes. The fundamental difference in the electrostatic surface potentials, cavity polarities, and shapes of the two macrocyclic hosts could account for the formation of the different inclusion complexes with distinct luminescence responses.

1 aGangopadhyay, Monalisa1 aMandal, Amal, K.1 aMaity, Arunava1 aRavindranathan, Sapna1 aRajamohanan, Pattuparambil, R.1 aDas, Amitava uhttps://library.ncl.res.in/content/tuning-emission-responses-triphenylamine-derivative-host-guest-complexes-and-unusual-101189nas a2200229 4500008004100000022001400041245011500055210006900170260000800239300001400247490000700261520041100268100001500679700001600694700002500710700001800735700002000753700002100773700002000794700001700814856012800831 2018 eng d a1359-734500aTracking HOCl concentrations across cellular organelles in real time using a super resolution microscopy probe0 aTracking HOCl concentrations across cellular organelles in real  cFEB a1849-18520 v543 a

BODIPY derivative, SF-1, exclusively shows a fluorescence ON response to HOCl and images endogenously generated HOCl in RAW 264.7 macrophages. Widefield and super resolution structured illumination microscopy images confirm localization in the Golgi complex and lysosomes, and hence specifically detects HOCl generated in these organelles. SF-1 is compatible with 3D-SIM imaging of individual cells.

1 aAli, Firoj1 aAute, Sunil1 aSreedharan, Sreejesh1 aAnila, H., A.1 aSaeed, Hiwa, K.1 aSmythe, Carl, G.1 aThomas, Jim, A.1 aDas, Amitava uhttps://library.ncl.res.in/content/tracking-hocl-concentrations-across-cellular-organelles-real-time-using-super-resolution