01062nas a2200169   4500008004100000022001400041245005800055210005400113260010600167300001000273490000700283520044100290100002600731700002500757700002200782856008800804       2009                        eng d  a0957-416600aConcise enantioselective synthesis of (+)-febrifugine0 aConcise enantioselective synthesis of febrifugine  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcJAN  a84-880 v203 a<p>A short enantioselective synthesis of (+)-febrifugine, a potent antimalarial alkaloid, has been described based on the regioselective asymmetric dihydroxylation of a 1,4-dienic ester as the key step. The strategy also involves chemoselective [3,3]-sigmatropic rearrangement of 1,5-hexadiene-3-ol and intramolecular lactamization of azidolactone for the construction of piperidine core. (C) 2008 Elsevier Ltd. All rights reserved.</p>1 aEmmanuvel, Lourdusamy1 aKamble, Dayanand, A.1 aSudalai, Arumugam  uhttps://library.ncl.res.in/content/concise-enantioselective-synthesis-febrifugine-001271nas a2200241   4500008004100000022001400041245009400055210006900149260010600218300001400324490000700338520036200345653001200707653001700719653002100736653002100757653002100778100002500799700002600824700003200850700002200882856012500904       2012                        eng d  a0040-403900aNaIO4-NaN3-mediated diazidation of styrenes, alkenes, benzylic alcohols, and aryl ketones0 aNaIO4NaN3mediated diazidation of styrenes alkenes benzylic alcoh  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcAUG  a4195-41980 v533 a<p>Sodium periodate and sodium azide combination has been found to be an excellent reagent system suitable for the direct diazidation of styrenes, alkenes, benzylic alcohols, and aryl ketones to produce the corresponding vicinal and geminal diazides respectively in high yields under mild reaction conditions. (C) 2012 Elsevier Ltd. All rights reserved.</p>10aalkenes10aAryl ketones10aGeminal diazides10aSodium periodate10aVicinal diazides1 aKamble, Dayanand, A.1 aKarabal, Pratibha, U.1 aChouthaiwale, Pandurang, V.1 aSudalai, Arumugam  uhttps://library.ncl.res.in/content/naio4-nan3-mediated-diazidation-styrenes-alkenes-benzylic-alcohols-and-aryl-ketones-001237nas a2200169   4500008004100000022001400041245018500055210006900240260011000309300001400419490000700433520042500440100002600865700002500891700002200916856012900938       2014                        eng d  a1477-052000aCo(III)(salen)-catalyzed phenolic kinetic resolution of two stereocentered benzyloxy and azido epoxides: its application in the synthesis of ICI-118,551, an anti-hypertensive agent0 aCoIIIsalencatalyzed phenolic kinetic resolution of two stereocen  aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcFEB  a2349-23550 v123 a<p>The salen Co(III)-catalyzed phenolic kinetic resolution of racemic anti- or syn-azido and benzyloxy epoxides provides a practical route to a range of enantioenriched anti-or syn-1-aryloxy-3-azido or benzyloxy-2-alcohols in excellent yields and ees. The synthetic potential of this protocol is illustrated with an enantioselective synthesis of ICI-118,551, a beta-blocker, in a highly optically pure form (99% ee).</p>1 aKarabal, Pratibha, U.1 aKamble, Dayanand, A.1 aSudalai, Arumugam  uhttps://library.ncl.res.in/content/coiiisalen-catalyzed-phenolic-kinetic-resolution-two-stereocentered-benzyloxy-and-azido-0