01215nas a2200181 4500008004100000022001400041245018400055210006900239260011000308300001400418490000700432520038000439100002100819700002300840700001700863700002200880856013100902 2014 eng d a1477-052000aIodine-catalyzed aromatization of tetrahydrocarbazoles and its utility in the synthesis of glycozoline and murrayafoline A: a combined experimental and computational investigation0 aIodinecatalyzed aromatization of tetrahydrocarbazoles and its ut aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcJUN a4832-48360 v123 a

A new protocol for the aromatization of tetrahydrocarbazoles has been achieved using a catalytic amount of iodine, giving high yields. The role of iodine in the aromatization has been explained by DFT, and its wide scope is extended to the total synthesis of glycozoline and murrayafoline A. This method has proven to be tolerant of a broad range of functional groups.

1 aHumne, Vivek, T.1 aDangat, Yuvraj, B.1 aVanka, Kumar1 aLokhande, Pradeep uhttps://library.ncl.res.in/content/iodine-catalyzed-aromatization-tetrahydrocarbazoles-and-its-utility-synthesis-glycozoline-001145nas a2200205 4500008004100000022001400041245013700055210006900192260000800261300001400269490000700283520039700290100002100687700002100708700002500729700001900754700001700773700002200790856012700812 2022 eng d a1477-052000aDirect oxidation of bromo-derived Fischer-Borsche oxo-ring using molecular iodine with combined experimental and computational study0 aDirect oxidation of bromoderived FischerBorsche oxoring using mo cJUL a5726-57290 v203 a

A direct oxidation of the bromo-derived Fischer-Borsche oxo-ring leading to carbazolequinone has been developed by using molecular iodine. This unprecedented transformation has been used for the modular synthesis of the anti-cardiotonic agent murrayaquinone. Furthermore, the present method has been generalized to a broad range of functional groups, with good to excellent yield.

1 aHumne, Vivek, T.1 aGhom, Monica, H.1 aNaykode, Mahavir, S.1 aDangat, Yuvraj1 aVanka, Kumar1 aLokhande, Pradeep uhttps://library.ncl.res.in/content/direct-oxidation-bromo-derived-fischer-borsche-oxo-ring-using-molecular-iodine-combined