02182nas a2200157   4500008004100000022001400041245015100055210006900206260011000275300001400385490000700399520145000406100002301856700002101879856012401900       2014                        eng d  a1477-052000aOne molecule of ionic liquid and tert-alcohol on a polystyrene-support as catalysts for efficient nucleophilic substitution including fluorination0 aOne molecule of ionic liquid and tertalcohol on a polystyrenesup  aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcOCT  a9264-92710 v123 a<p>The tert-alcohol and ionic liquid solvents in one molecule [mim-(OH)-O-t][OMs] was immobilized on polystyrene and reported to be a highly efficient catalyst in aliphatic nucleophilic substitution using alkali metal salts. Herein, we investigated the catalytic activity of a new structurally modified polymer-supported tert-alcohol functionalized imidazolium salt catalyst in nucleophilic substitution of 2-(3-methanesulfonyl-oxypropyoxy) naphthalene as a model substrate with various metal nucleophiles. The tert-alcohol moiety of the ionic liquid with a hexyl chain distance from polystyrene had a better catalytic activity compared to the other resin which lacked an alkyl linker and tert-alcohol moiety. We found that the maximum [mim-(OH)-O-t][OMs] loading had the best catalytic efficacy among the tested polystyrene-based ionic liquids (PSILs) in nucleophilic fluorination. The catalytic efficiency of the PS[him-(OH)-O-t][OMs] as a phase transfer catalyst (PTC) was determined by carrying out various nucleophilic substitutions using the corresponding alkali metal salts from the third to sixth periodic in CH3CN or tert-BuOH media. The scope of this protocol with primary and secondary polar substrates containing many heteroatoms is also reported. This PS [him-(OH)-O-t][OMs] catalyst not only enhances the reactivity of alkali metal salts and reduces the formation of by-products but also affords high yield with easy isolation.</p>1 aShinde, Sandip, S.1 aPatil, Sunil, N.  uhttps://library.ncl.res.in/content/one-molecule-ionic-liquid-and-tert-alcohol-polystyrene-support-catalysts-efficient-0