01414nas a2200217   4500008004100000022001400041245016700055210006900222260010600291300001400397490000700411520053000418653001600948653001700964653001900981653001601000100002401016700001901040700001801059856011901077       2009                        eng d  a0040-403900aEfficient, rapid, and regioselective bromination of anilines and phenols with 1-butyl-3-methylpyridinium tribromide as a new reagent/solvent under mild conditions0 aEfficient rapid and regioselective bromination of anilines and p  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcMAR  a1007-10090 v503 a<p>1-Butyl-3-methylpyridinium tribromide, [BMPy]Br(3) proves to be a highly efficient, regioselective reagent/solvent for nuclear bromination of various anilines and phenols. The synthesis and characterization of the room temperature ionic liquid [BMPy]Br(3) (2) is described. The bromination was carried out in the absence of organic solvents and in most cases the only extraction solvent needed was water. The spent 1-butyl-3-methylpyridinium bromide (1) was easily recycled. (C) 2008 Elsevier Ltd. All rights reserved.</p>10aBromination10aIonic liquid10aRegioselective10a[BMPy]Br(3)1 aBorikar, Sanjay, P.1 aDaniel, Thomas1 aPaul, Vincent  uhttps://library.ncl.res.in/content/efficient-rapid-and-regioselective-bromination-anilines-and-phenols-1-butyl-3-001372nas a2200229   4500008004100000022001400041245011600055210006900171260008600240300001800326490000700344520051400351653001700865653002000882653001900902653001700921653001400938100002400952700001900976700001800995856012901013       2010                        eng d  a0039-791100aMild, efficient, and regioselective monobromination of arylamines and phenols using [BBIm]Br-3 as a new reagent0 aMild efficient and regioselective monobromination of arylamines   a325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USAbTAYLOR & FRANCIS INCcAPR  aPII 9190830740 v403 a<p>We report here an efficient method for the synthesis and characterization of the room-temperature ionic liquid 1,3-di-n-butylimidazolium tribromide ([BBIm]Br-3) (2) and its application as an efficient reagent and solvent for regioselective bromination of arylamines and phenols under mild conditions. The bromination was carried out in the absence of organic solvents, and in most cases, the only extraction solvent needed was water. The spent 1,3-di-n-butylimidazolium bromide (1) was easily recycled.</p>10aIonic liquid10amonobromination10aRegioselective10aSolvent-free10a[BBIm]Br31 aBorikar, Sanjay, P.1 aDaniel, Thomas1 aPaul, Vincent  uhttps://library.ncl.res.in/content/mild-efficient-and-regioselective-monobromination-arylamines-and-phenols-using-bbimbr-3-001084nas a2200205   4500008004100000022001400041245010700055210006900162260008600231300001800317490000700335520028400342653001800626653001900644653002700663653002100690100002400711700001800735856012500753       2010                        eng d  a0039-791100aN-nitrosation of secondary amines using p-TSA-NaNO2 as a novel nitrosating agent under mild conditions0 aNnitrosation of secondary amines using pTSANaNO2 as a novel nitr  a325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USAbTAYLOR & FRANCIS INCcFEB  aPII 9190826580 v403 a<p>A combination of p-toluenesulfonic acid (p-TSA) and sodium nitrite was used as a novel effective nitrosating agent for the N-nitrosation of secondary amines to their corresponding nitroso derivatives under mild and heterogeneous conditions in moderate to excellent yields.</p>10aN-nitrosation10anitroso amines10ap-toluenesulfonic acid10asecondary amines1 aBorikar, Sanjay, P.1 aPaul, Vincent  uhttps://library.ncl.res.in/content/n-nitrosation-secondary-amines-using-p-tsa-nano2-novel-nitrosating-agent-under-mild-001343nas a2200217   4500008004100000022001400041245014700055210006900202260005700271300001200328490000600340520051900346653001600865653002000881653001700901653001700918653001500935100002400950700001900974856013200993       2011                        eng d  a1735-207X00aAromatic bromination of aldehydes and ketones using 1,3-di-n-butylimidazolium tribromide [BBIm]Br3 ionic liquids under solvent-free conditions0 aAromatic bromination of aldehydes and ketones using 13dinbutylim  a233 SPRING ST, NEW YORK, NY 10013 USAbSPRINGERcJUN  a531-5360 v83 a<p>An environmentally benign and efficient process for the preparation of monobromo derivatives of aryl aldehydes and ketones was developed by simple and practical reactions of aryl aldehydes or ketones with 1,3-di-n-butylimidazolium tribromide ([BBIm]Br-3), as a brominating reagent under solvent-free conditions in very high yields. The process has several advantages: high conversions, short reaction time, mild reaction conditions, simple workup with good to quantitative yields and re-usable ionic liquid.</p>10aBromination10agreen chemistry10aIonic liquid10aSolvent-free10a[BBIm]Br-31 aBorikar, Sanjay, P.1 aDaniel, Thomas  uhttps://library.ncl.res.in/content/aromatic-bromination-aldehydes-and-ketones-using-13-di-n-butylimidazolium-tribromide-bbimbr301397nas a2200241   4500008004100000022001400041245013900055210006900194260007300263300001200336490000700348520048800355653000600843653004800849653001700897653001200914653001700926653001700943653002700960100002400987700001901011856012501030       2011                        eng d  a1350-417700aConvenient and efficient protocol for the synthesis of acylals catalyzed by bronsted acidic ionic liquids under ultrasonic irradiation0 aConvenient and efficient protocol for the synthesis of acylals c  aPO BOX 211, 1000 AE AMSTERDAM, NETHERLANDSbELSEVIER SCIENCE BVcSEP  a928-9310 v183 a<p>The synthesis of acylals (1,1-diacetates) via the reactions of aldehydes with acetic anhydride was carried Out in 85-97% yields at room temperature under ultrasound irradiation catalyzed by the Bronsted acidic ionic liquid [bmpy]HSO(4). This method provides several advantages, such as solvent-free conditions, operational simplicity, higher yields, and reduced environmental consequences. The ionic liquid was recovered and reused. (C) 2011 Elsevier B.V. All rights reserved.</p>10a110a1-Butyl-3-methylpyridinium hydrogen sulfate10a1-Diacetates10aAcylals10aIonic liquid10aSolvent-free10aUltrasonic irradiation1 aBorikar, Sanjay, P.1 aDaniel, Thomas  uhttps://library.ncl.res.in/content/convenient-and-efficient-protocol-synthesis-acylals-catalyzed-bronsted-acidic-ionic-001412nas a2200253   4500008004100000022001400041245011200055210006900167260007500236300001400311520049400325653001600819653002000835653001900855653001400874653001400888100002400902700001800926700002600944700002100970700002700991700001901018856012101037       2011                        eng d  a0039-788100aFirst total synthesis of 5-hydroxy-3-methyl-4-propylsulfanyl-5H-furan-2-one: a cancer chemopreventive agent0 aFirst total synthesis of 5hydroxy3methyl4propylsulfanyl5Hfuran2o  aRUDIGERSTR 14, D-70469 STUTTGART, GERMANYbGEORG THIEME VERLAG KGcMAY  a1595-15983 a<p>The first total synthesis of 5-hydroxy-3-methyl-4-propylsulfanyl-5H-furan-2-one, a newly discovered natural product with anticancer property is described by two different routes. A sequence involving an incorporation of a methyl group via a Gilman reagent and a chemoselective reduction of a cyclic anhydride functionality are the key steps. The methods proposed start from easily available starting materials and allow ready preparation of the final compound in good overall yield.</p>10aAllium cepa10achemopreventive10aGilman reagent10aselective10asynthesis1 aBorikar, Sanjay, P.1 aPaul, Vincent1 aPuranik, Vedavati, G.1 aSathe, Vilas, T.1 aLagunas-Rivera, Selene1 aOrdonez, Mario  uhttps://library.ncl.res.in/content/first-total-synthesis-5-hydroxy-3-methyl-4-propylsulfanyl-5h-furan-2-one-cancer-002740nas a2200277   4500008004100000022001400041245017800055210006900233260010600302300001000408490000700418520166900425653000802094653002702102653001602129653000902145653002002154653001202174100002502186700002402211700002402235700002502259700002602284700002102310856013102331       2014                        eng d  a0031-942200aDifferential transcriptional activity of SAD, FAD2 and FAD3 desaturase genes in developing seeds of linseed contributes to varietal variation in alpha-linolenic acid content0 aDifferential transcriptional activity of SAD FAD2 and FAD3 desat  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcFEB  a41-530 v983 a<p>Linseed or flax (Linum usitatissimum L.) varieties differ markedly in their seed a-linolenic acid (ALA) levels. Fatty acid desaturases play a key role in accumulating ALA in seed. We performed fatty acid (FA) profiling of various seed developmental stages of ten Indian linseed varieties including one mutant variety. Depending on their ALA contents, these varieties were grouped under high ALA and low ALA groups. Transcript profiling of six microsomal desaturase genes (SAD1, SAD2, FAD2, FAD2-2, FAD3A and FAD3B), which act sequentially in the fatty acid desaturation pathway, was performed using real-time PCR. We observed gene specific as well as temporal expression pattern for all the desaturases and their differential expression profiles corresponded well with the variation in FA accumulation in the two groups. Our study points to efficient conversion of intermediate FAs [stearic (SA), oleic (OA) and linoleic acids (LA)] to the final product, ALA, due to efficient action of all the desaturases in high ALA group. While in the low ALA group, even though the initial conversion up to OA was efficient, later conversions up to ALA seemed to be inefficient, leading to higher accumulation of OA and LA instead of ALA. We sequenced the six desaturase genes from the ten varieties and observed that variation in the amino acid (AA) sequences of desaturases was not responsible for differential ALA accumulation, except in the mutant variety TL23 with very low (&lt;2%) ALA content. In TL23, a point mutation in the FAD3A gene resulted into a premature stop codon generating a truncated protein with 291 AA. (C) 2013 Elsevier Ltd. All rights reserved.</p>10aALA10aFatty acid desaturases10aFatty acids10aFlax10aGene expression10aLinseed1 aRajwade, Ashwini, V.1 aKadoo, Narendra, Y.1 aBorikar, Sanjay, P.1 aHarsulkar, Abhay, M.1 aGhorpade, Prakash, B.1 aGupta, Vidya, S.  uhttps://library.ncl.res.in/content/differential-transcriptional-activity-sad-fad2-and-fad3-desaturase-genes-developing-seeds-001387nas a2200229   4500008004100000022001400041245012200055210006900177260000800246300001200254490000700266520058600273653001300859653001400872653002000886653002900906653001600935100002900951700002400980700002201004856013101026       2015                        eng d  a1863-065000aSynthesis of non-toxic triethyl citrate plasticizer by esterification of renewable citric acid using modified zeolite0 aSynthesis of nontoxic triethyl citrate plasticizer by esterifica  cJUN  a927-9310 v433 a<p>Triethyl citrate (TEC), a non-toxic plasticizer, was synthesized by esterification of renewable citric acid (CA, from entire waste of oranges) with ethanol over modified H-ZSM-5 (HZ-5) zeolite. Different micro-meso composites (M-HZ-5) with varying crystallinities were prepared by alkaline treatment of HZ-5. M-HZ-5(0.6) (87% crystallinity) was observed to be a potential and environmentally benign catalyst with 96% CA conversion, 64% TEC selectivity (61.44% TEC yield), and a reusability of six cycles. The probable catalytic mechanism of esterification was also proposed.</p>10aBiowaste10aCatalysts10agreen chemistry10aMicro-mesopre composites10areusability1 aNandiwale, Kakasaheb, Y.1 aBorikar, Sanjay, P.1 aBokade, Vijay, V.  uhttps://library.ncl.res.in/content/synthesis-non-toxic-triethyl-citrate-plasticizer-esterification-renewable-citric-acid-using