01970nas a2200181 4500008004100000022001400041245013000055210006900185260011000254300001600364490000600380520119400386100001701580700001901597700001901616700002101635856013201656 2013 eng d a2046-206900aChemically conjugated sophorolipids on CdTe QDs: a biocompatible photoluminescence nanocomposite for theranostic applications0 aChemically conjugated sophorolipids on CdTe QDs a biocompatible  aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcSEP a22319-223250 v33 a

Functional nontoxic cadmium telluride (CdTe) quantum dots (QDs) have been synthesized using a natural functional glycolipid belonging to the family of sophorolipids (SL) as a surface-modifying agent. These SLs with open acidic form are highly suitable for QDs stabilization, are readily obtained by a fermentation process of the yeast Candida bombicola (polymorph Starmerella bombicola) in large amounts. In this work chemically stable, water soluble, and photoluminescent CdTe QDs were successfully conjugated to sophorolipids via a cross-linking reaction. The formation of SLs conjugated CdTe QDs was confirmed using different analytical techniques X-ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), Transmission Electron Microscopy (TEM), Electron Diffraction (ED), Atomic Force Microscopy (AFM), Dynamic Light Scattering (DLS), and Photoluminescence (PL). It was shown that after being conjugated with SL the SL-CdTe QDs becomes biocompatible, still maintaining its water solubility and photoluminescence properties. The final SL coated photoluminescent CdTe QDs represent interesting biocompatible materials potentially useful for biomedical applications.

1 aSingh, Pooja1 aJoshi, Kasturi1 aGuin, Debanjan1 aPrabhune, Asmita uhttps://library.ncl.res.in/content/chemically-conjugated-sophorolipids-cdte-qds-biocompatible-photoluminescence-nanocomposite-001673nas a2200181 4500008004100000022001400041245010700055210006900162260011000231300001400341490000600355520091600361100001701277700002101294700002901315700001901344856012801363 2013 eng d a2050-750X00aGlucose oxidase conjugated H2O2 sensitive CdTe QDs: an effective fluorescence tool for glucose sensing0 aGlucose oxidase conjugated H2O2 sensitive CdTe QDs an effective  aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcOCT a6538-65430 v13 a

Water-soluble quantum dots (QDs) are extensively used for molecular sensing because of the flexibility they offer in terms of modification of the QDs surface with a variety of functional groups using thiol chemistry and monitoring by fluorescence intensity. We describe a simple assay that allows the photoluminescence (PL) detection of H2O2 and glucose in aqueous samples and demonstrate its applicability by estimating glucose in blood. To enable the glucose detection, we functionalized the 3-mercaptopropanoic acid (MPA) capped CdTe QDs with glucose oxidase (GOx), the enzyme specific to b-D-glucose, using carbodiimide chemistry. The fluorescence of the GOx-functionalized CdTe QDs was quenched on the interaction with glucose. The same photoluminescence quenching was also observed in gel form, when a GOx modified CdTe QDs loaded agarose gel was dipped in H2O2 and glucose solutions, respectively.

1 aSingh, Pooja1 aPrabhune, Asmita1 aOgale, Satishchandra, B.1 aGuin, Debanjan uhttps://library.ncl.res.in/content/glucose-oxidase-conjugated-h2o2-sensitive-cdte-qds-effective-fluorescence-tool-glucose-001262nas a2200217 4500008004100000022001400041245014200055210006900197260007700266300001200343490000700355520041700362653001500779653001800794653002600812653002800838653001300866100001900879700001700898856012900915 2014 eng d a0934-086600aBlue luminescent graphene quantum dots by photochemical stitching of small aromatic molecules: fluorescent nanoprobes in cellular imaging0 aBlue luminescent graphene quantum dots by photochemical stitchin aBOSCHSTRASSE 12, D-69469 WEINHEIM, GERMANYbWILEY-V C H VERLAG GMBHcAPR a433-4380 v313 a

Blue fluorescent graphene quantum dots (GQDs) are synthesized from small haloaromatic molecules by laser photochemistry. The process involves a bottom-up photochemical stitching mechanism of the free radicals generated by irradiation of ultraviolet photons (lambda = 248 nm) on o-dichlorobenzene. The GQDs are further demonstrated to be of importance as fluorescent nanoprobes in bioimaging of cells.image

10abioimaging10afree radicals10agraphene quantum dots10aphotochemical stitching10aUV laser1 aGokhale, Rohan1 aSingh, Pooja uhttps://library.ncl.res.in/content/blue-luminescent-graphene-quantum-dots-photochemical-stitching-small-aromatic-molecules-0