01377nas a2200169   4500008004100000022001400041245018000055210006900235260000900304300001400313490000700327520066700334100002801001700002401029700002401053856013001077       2025                        eng d  a1523-706000aDiastereoselective synthesis of cyclic and spirocyclic quaternary carbons via iron-catalyzed ring contraction of cyclic ketones: a formal synthesis of perhydrohistrionicotoxin0 aDiastereoselective synthesis of cyclic and spirocyclic quaternar  cAUG   a8798-88030 v273 a<p>
	The iron-catalyzed hydrogen atom transfer (HAT)-initiated Dowd-Beckwith rearrangement presents a new approach for synthesizing cyclic and spirocyclic quaternary carbons from readily available beta-keto esters and cyclic diketones with high yields. This reaction proceeds in a stereocontrolled manner, enabling the formation of synthetically valuable cyclic ketones with two contiguous stereocenters, including quaternary centers. This transformation introduces an innovative bond disconnection strategy for ring-contraction reactions. Additionally, a short formal synthesis of perhydrohistrionicotoxin was efficiently achieved using this methodology.</p>
1 aSurvase, Vijayanand, U.1 aRokade, Avinash, D.1 aHandore, Kishor, L.  uhttps://library.ncl.res.in/content/diastereoselective-synthesis-cyclic-and-spirocyclic-quaternary-carbons-iron-catalyzed-ring01502nas a2200169   4500008004100000022001400041245011400055210006900169260000900238300001600247490000700263520085900270100002301129700002401152700002401176856013201200       2025                        eng d  a0022-326300aSynthesis of Readily Modifiable Amides from Aldehydes via an Organocatalytic Approach Using a CTAB Surfactant0 aSynthesis of Readily Modifiable Amides from Aldehydes via an Org  cAUG   a11288-113000 v903 a<p>A simple and efficient organocatalytic method has been developed to access ``readily modifiable'' amides, including bench-stable N-acyl saccharin and various activated amides, from aldehydes by using CTAB- t BuOOH. A wide range of aromatic and aliphatic acyl saccharin are obtained from their respective aldehydes with moderate to good yields. The approach can be similarly applied toward the formation of N-acyl imidazole, N-acyl benzimidazole, N-methoxy-N-methylamide (Weinreb amide), N-ethyl-N-phenylbenzamide, N-acyl morpholine, N-acyl valerolactam, and N-acyl caprolactam. These compounds are frequently applied as reagents in organic transformations, including acyl coupling, decarbonylative coupling, radical coupling, and coupling that is free from transition metals, enabling the synthesis of new C-C, C-N, C-O, C-S, C-P, and C-B bonds.</p>
1 aAkhade, Akshay, M.1 aRokade, Avinash, D.1 aHandore, Kishor, L.  uhttps://library.ncl.res.in/content/synthesis-readily-modifiable-amides-aldehydes-organocatalytic-approach-using-ctab-surfactant