01261nas a2200169   4500008004100000245012300041210006900164260000800233300001400241490000700255520061200262100002300874700002400897700002100921700002600942856012300968       2025                        eng d00aSeparation of isomers of chiral thiourea derivatives via spontaneous resolution and rationale of molecular recognition0 aSeparation of isomers of chiral thiourea derivatives via spontan  cFEB  a1240-12470 v273 a<p>
	Enrichment of enantiomers during crystallization of racemic thiourea derivatives was investigated. The spontaneous resolution of a chiral thiourea derivative via preferential crystallization is attributed to thermodynamic stability when molecules of identical chirality bind with each other in the crystal lattice. Single crystal X-ray analysis reveals the interactions responsible for self-recognition of molecules of the same chirality in the unit cell. The tendency of the thiourea derivative to form a conglomerate is supported by IR spectroscopy, thermal analysis and computational studies.</p>
1 aDwivedi, Astha, M.1 aGonnade, Rajesh, G.1 aSahoo, Suban, K.1 aBedekar, Ashutosh, V.  uhttps://library.ncl.res.in/content/separation-isomers-chiral-thiourea-derivatives-spontaneous-resolution-and-rationale