00868nas a2200229   4500008004100000245011500041210006900156260000800225490000700233653002700240653002500267653003000292653002800322100002500350700001900375700002400394700001800418700003000436700003100466700002000497856012100517       2024                        eng d00aExtrusion 3D printing of intrinsically fluorescent thermoplastic polyimide: revealing an undisclosed potential0 aExtrusion 3D printing of intrinsically fluorescent thermoplastic  cOCT0 v1610aAdditive manufacturing10afunctional extrusion10ahigh-performance polymers10athermoplastic polyimide1 aKothavade, Premkumar1 aKafi, Abdullah1 aDekiwadia, Chaitali1 aKumar, Viksit1 aSukumaran, Santhosh, Babu1 aShanmuganathan, Kadhiravan1 aBateman, Stuart  uhttps://library.ncl.res.in/content/extrusion-3d-printing-intrinsically-fluorescent-thermoplastic-polyimide-revealing02550nas a2200217   4500008004100000022001400041245011000055210006900165260000900234300001600243490000700259520177100266100002102037700002602058700002402084700002402108700002002132700002702152700002702179856012602206       2025                        eng d  a2050-750X00aDesign, fabrication and comprehensive testing of biodegradable 3D printable hybrid polymer airway splints0 aDesign fabrication and comprehensive testing of biodegradable 3D  cAUG   a10249-102660 v133 a<p>
	The trachea plays a critical role in respiration and airway protection but is susceptible to damage from pathological conditions such as stenosis, fistula, obstruction, and malacia. While existing treatment options are useful, they often have limitations, driving the need for innovative alternatives. This study introduces a novel approach using 3D printing technology to create hybrid degradable tracheal splints made of pectin-g-polycaprolactone (pec-g-PCL). We synthesized and characterized various compositions of pec-g-PCL to assess their physicochemical properties and tested their suitability for 3D printing. The resulting materials demonstrated the potential for use as tracheal splints. Using CAD software, we created two distinct designs, which were then fabricated according to those specifications. Micro-computed tomography (micro-CT) imaging revealed splint porosities ranging from 80% to 90%, highlighting their intricate internal microarchitecture. Design verification was conducted through numerical simulations, based on finite element modeling (FEM), to evaluate mechanical properties and computational fluid dynamics (CFD) for assessing the airflow dynamics of the fabricated tracheal splints. Degradation studies indicated that the 3D-printed scaffolds exhibited approximately 30% degradation over a period of 35 days. In vitro, biocompatibility assessments confirmed the scaffold's compatibility with biological systems. These findings demonstrate the potential of pec-g-PCL-based tracheal splints as a promising solution to overcome limitations in current treatments. This research paves the way for advanced biomaterials that could revolutionize patient care by offering more effective solutions for managing tracheal disorders.</p>
1 aNaik, Sonali, S.1 aVongsvivut, Jitraporn1 aDekiwadia, Chaitali1 aAbraham, Amanda, N.1 aDutta, Naba, K.1 aChoudhury, Namita, Roy1 aNair, Kiran, Sukumaran  uhttps://library.ncl.res.in/content/design-fabrication-and-comprehensive-testing-biodegradable-3d-printable-hybrid-polymer