02269nas a2200241 4500008004100000022001400041245016300055210006900218260000800287300001200295490000800307520137700315653003101692653002701723653001401750653002801764100001801792700002401810700002101834700001901855700002101874856013201895 2024 eng d a0026-924700aFerric oxide nanocatalyst: synthesis, characterization, and application in the one-pot three-component synthesis of 3,4,5-trisubstituted isoxazole derivatives0 aFerric oxide nanocatalyst synthesis characterization and applica cJUN a631-6410 v1553 a

In this study, we have focused on the preparation and application of a nano-ferric oxide catalyst as a heterogeneous catalyst in the one-pot, three-component synthesis of isoxazole derivatives. The ferric oxide catalyst was synthesized using a simple precipitation method and thoroughly characterized using techniques such as FT-IR, XRD, SEM, EDX, and BET. The effectiveness of the ferric oxide catalyst as a heterogeneous catalyst was investigated in the synthesis of 3,4,5-trisubstituted isoxazole. The results of the synthesis demonstrated that the catalyst exhibited high efficiency in facilitating the three-component, one-pot synthesis of 3,4,5-trisubstituted isoxazole derivatives. The synthesis route employed in this study offers several advantages, including its simplicity, ease of workup, and environmental friendliness. Furthermore, the catalyst was successfully recovered and reused for five cycles without experiencing a significant loss in catalytic activity. This finding highlights the excellent stability and promising potential of the catalyst for organic transformations. Overall, our study showcases the successful preparation and application of the nano-ferric oxide catalyst in the synthesis of isoxazole derivatives, providing valuable insights into its catalytic performance and potential for future applications in organic chemistry.

10aFerric oxide nanoparticles10aheterogeneous catalyst10aIsoxazole10aMulticomponent reaction1 aTotre, Ganesh1 aShinde, Dnyaneshwar1 aShirsath, Sachin1 aPatil, Prakash1 aKulkarni, Pramod uhttps://library.ncl.res.in/content/ferric-oxide-nanocatalyst-synthesis-characterization-and-application-one-pot-three-component01309nas a2200253 4500008004100000022001400041245010400055210006900159260000800228300001500236490000700251520048200258653000600740653002500746653001500771653002000786653001900806653001700825653001800842100002100860700002100881700002200902856013100924 2025 eng d a2365-654900aIron mediated oxidative ring opening-homocoupling of cyclopropanols: facile access to 1,6-diketones0 aIron mediated oxidative ring openinghomocoupling of cyclopropano cMAY ae2025017450 v103 a

We have developed a new approach for the synthesis of 1,6-diketones via iron-catalyzed ring opening of cyclopropanol with a nontoxic, inexpensive iron catalyst under open-air conditions. This method eliminates the need for additives and employs tert-butanol as an eco-friendly solvent. This methodology allows rapid access to a variety of symmetrical 1,6-diketones under mild conditions. Preliminary mechanistic studies revealed the involvement of radical pathways.

10a110a6-Diketone synthesis10aC & horbar10aC bond cleavage10acyclopropanols10aHomocoupling10aIron mediated1 aShinde, Ravi, A.1 aShirsath, Sachin1 aMuthukrishnan, M. uhttps://library.ncl.res.in/content/iron-mediated-oxidative-ring-opening-homocoupling-cyclopropanols-facile-access-16-diketones