01663nas a2200253   4500008004100000022001400041245015600055210006900211260010300280300001200383490000700395520063000402653002501032653004301057653001701100653002901117653001901146100002701165700002201192700002001214700001801234700002801252856012901280       2013                        eng d  a1631-074800aDiethylamine: a smart organocatalyst in eco-safe and diastereoselective synthesis of medicinally privileged 2-amino-4H-chromenes at ambient temperature0 aDiethylamine a smart organocatalyst in ecosafe and diastereosele  a23 RUE LINOIS, 75724 PARIS, FRANCEbELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIERcAUG  a689-6950 v163 a<p>Diethylamine has been demonstrated to be an efficient organocatalyst in the diastereoselective synthesis of Bcl-2 protein antagonist (HA-14-1) and of its structural analogues by one-pot condensation between salicylaldehyde and three different C-H acids, viz, ethyl cyanoacetate, phenylsulfonyl acetonitrile, and malononitrile. Easy commercial availability of the catalyst at extremely low cost and avoidance of conventional work-up as well as purification procedures qualifies this scalable protocol for a ``near-ideal synthesis''. (c) 2013 Academie des sciences. Published by Elsevier Masson SAS. All rights reserved.</p>10a2-amino-4H-chromenes10aActive methylene compounds (C-H acids)10adiethylamine10amulticomponent reactions10aorganocatalyst1 aKulkarni, Makarand, A.1 aPandit, Kapil, S.1 aDesai, Uday, V.1 aLad, Uday, P.1 aWadgaonkar, Prakash, P.  uhttps://library.ncl.res.in/content/diethylamine-smart-organocatalyst-eco-safe-and-diastereoselective-synthesis-medicinally-001464nas a2200241   4500008004100000022001400041245013600055210006900191260010300260300001200363490000700375520049700382653003100879653002300910653002400933653001700957100002700974700001801001700002001019700002701039700002801066856012801094       2013                        eng d  a1631-074800aMechanistic approach for expeditious and solvent-free synthesis of alpha-hydroxy phosphonates using potassium phosphate as catalyst0 aMechanistic approach for expeditious and solventfree synthesis o  a23 RUE LINOIS, 75724 PARIS, FRANCEbELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIERcFEB  a148-1520 v163 a<p>An extremely simple, high yielding, highly rapid and solvent-free protocol has been described for hydrophosphylation of aldehydes using potassium phosphate as catalyst. Easy commercial availability of the reusable catalyst, operational simplicity at ambient temperature and avoidance of conventional work-up as well as purification procedure makes this solvent-free protocol a near-ideal synthesis. (C) 2012 Academie des sciences. Published by Elsevier Masson SAS. All rights reserved.</p>10aalpha-hydroxy phosphonates10aHydrophosphylation10aPotassium phosphate10aSolvent-free1 aKulkarni, Makarand, A.1 aLad, Uday, P.1 aDesai, Uday, V.1 aMitragotri, Satish, D.1 aWadgaonkar, Prakash, P.  uhttps://library.ncl.res.in/content/mechanistic-approach-expeditious-and-solvent-free-synthesis-alpha-hydroxy-phosphonates-001390nas a2200193   4500008004100000022001400041245018500055210006900240260011000309300001600419490000600435520051000441100002300951700002200974700002000996700002701016700002801043856012501071       2014                        eng d  a2046-206900aCellulose supported cuprous iodide nanoparticles (Cell-CuI NPs): a new heterogeneous and recyclable catalyst for the one pot synthesis of 1,4-disubstituted-1,2,3-triazoles in water0 aCellulose supported cuprous iodide nanoparticles CellCuI NPs a n  aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcSEP  a42137-421460 v43 a<p>Cellulose supported cuprous iodide nanoparticles (Cell-CuI NPs) have been demonstrated for the first time as an efficient heterogeneous catalyst in the click synthesis of 1,4-disubstituted 1,2,3-triazoles by a one-pot three component reaction between aralkyl/alkyl bromides, alkynes and sodium azide in water. The catalyst has been characterized by XRD, HRTEM, SEM, ICP-AES, EDS as well as IR spectroscopy. It was found to be reusable for five consecutive runs without significant loss of activity.</p>1 aChavan, Pramod, V.1 aPandit, Kapil, S.1 aDesai, Uday, V.1 aKulkarni, Makarand, A.1 aWadgaonkar, Prakash, P.  uhttps://library.ncl.res.in/content/cellulose-supported-cuprous-iodide-nanoparticles-cell-cui-nps-new-heterogeneous-and-001351nas a2200193   4500008004100000022001400041245016800055210006900223260011000292300001600402490000600418520048800424100002500912700002000937700002200957700002700979700002801006856012301034       2014                        eng d  a2046-206900aNickel ferrite nanoparticles-hydrogen peroxide: a green catalyst-oxidant combination in chemoselective oxidation of thiols to disulfides and sulfides to sulfoxides0 aNickel ferrite nanoparticleshydrogen peroxide a green catalystox  aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcJUL  a36702-367070 v43 a<p>Nickel ferrite nanoparticles-hydrogen peroxide has been demonstrated for the first time as a green and efficient catalyst-oxidant combination in the chemoselective oxidation of thiols to disulfides and sulfides to sulfoxides. This magnetically separable catalyst was found to be reusable for five consecutive runs without appreciable change in the activity, as well as composition of the catalyst. The mechanism for the oxidation of thiols and sulfides has also been proposed.</p>1 aKulkarni, Aparna, M.1 aDesai, Uday, V.1 aPandit, Kapil, S.1 aKulkarni, Makarand, A.1 aWadgaonkar, Prakash, P.  uhttps://library.ncl.res.in/content/nickel-ferrite-nanoparticles-hydrogen-peroxide-green-catalyst-oxidant-combination-001472nas a2200265   4500008004100000022001400041245015100055210006900206260009200275300001200367490000600379520044600385653002200831653001700853653002000870653002900890653001900919653001500938100002000953700002700973700002201000700002501022700002801047856013101075       2014                        eng d  a1751-825300aSimple, economical, and environmentally benign protocol for the synthesis of 2-amino-3,5-dicarbonitrile-6-sulfanylpyridines at ambient temperature0 aSimple economical and environmentally benign protocol for the sy  a4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLANDbTAYLOR & FRANCIS LTDcJUN  a228-2350 v73 a<p>A simple, economical, and environmentally benign protocol has been described for one-pot synthesis of medicinally privileged 2-amino-3,5-dicarbonitrile-6-sulfanylpyridines by three-component condensation between aldehyde, malononitrile, and thiol using diethylamine as a catalyst. Ambient temperature and avoidance of conventional work-up as well as purification procedure qualify this cost-effective protocol for ``green synthesis.''</p>10a5-dicarbonitriles10adiethylamine10agreen chemistry10amulticomponent reactions10aorganocatalyst10apyridine-31 aDesai, Uday, V.1 aKulkarni, Makarand, A.1 aPandit, Kapil, S.1 aKulkarni, Aparna, M.1 aWadgaonkar, Prakash, P.  uhttps://library.ncl.res.in/content/simple-economical-and-environmentally-benign-protocol-synthesis-2-amino-35-dicarbonitrile-601497nas a2200193   4500008004100000022001400041245018800055210006900243260011000312300001400422490000700436520060900443100002201052700002301074700002001097700002701117700002801144856013101172       2015                        eng d  a1144-054600aTris-hydroxymethylaminomethane (THAM): a novel organocatalyst for a environmentally benign synthesis of medicinally important tetrahydrobenzo[b]pyrans and pyran-annulated heterocycles0 aTrishydroxymethylaminomethane THAM a novel organocatalyst for a   aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcMAR  a4452-44630 v393 a<p>simple, efficient and environmentally benign protocol has been developed for the one-pot, multicomponent synthesis of medicinally important tetrahydrobenzo[b]pyrans and pyran-annulated heterocycles using a commercially available, inexpensive, non-toxic, and biodegradable tris-hydroxymethylaminomethane (THAM) as a novel organocatalyst. Ambient reaction conditions, wide scope, avoidance of conventional isolation as well as purification techniques and the reusability of the catalyst for five consecutive runs have improved the practical utility of this multicomponent reaction protocol manifold.</p>1 aPandit, Kapil, S.1 aChavan, Pramod, V.1 aDesai, Uday, V.1 aKulkarni, Makarand, A.1 aWadgaonkar, Prakash, P.  uhttps://library.ncl.res.in/content/tris-hydroxymethylaminomethane-tham-novel-organocatalyst-environmentally-benign-synthesis-001141nas a2200181   4500008004100000245012900041210006900170260000800239300001400247490000700261520044000268100002600708700002200734700002000756700002700776700002800803856012800831       2016                        eng d00aDiethylamine-catalyzed environmentally benign synthesis of 1-oxo-hexahydroxanthenes and bis-coumarins at ambient temperature0 aDiethylaminecatalyzed environmentally benign synthesis of 1oxohe  cJUL  a6313-63250 v423 aAn extremely simple, economical and environmentally benign protocol has been described for one-pot synthesis of 1-oxo-hexahydroxanthenes by pseudo three-component condensation between salicylaldehydes and dimedone, cyclohexane-1,3dione or 5-methyl cyclohexane-1,3-dione using diethylamine as the catalyst. Based upon the mechanism of the reaction, the protocol has been extended towards the synthesis of tetraketones and bis-coumarins.1 aKupwade, Ravindra, V.1 aPandit, Kapil, S.1 aDesai, Uday, V.1 aKulkarni, Makarand, A.1 aWadgaonkar, Prakash, P.  uhttps://library.ncl.res.in/content/diethylamine-catalyzed-environmentally-benign-synthesis-1-oxo-hexahydroxanthenes-and-bis00682nas a2200157   4500008004100000245014500041210006900186260000800255490000600263100002200269700002700291700002700318700002000345700002900365856013000394       2021                        eng d00aHighly efficient and extremely simple protocol for the oxidation α-hydroxyphosphonates to α-ketophosphonates using Dess-Martin periodinane0 aHighly efficient and extremely simple protocol for the oxidation  cJAN0 v41 aKupwade, Ravindra1 aMitragotri, Satish, D.1 aKulkarni, Makarand, A.1 aDesai, Uday, V.1 aWadagaonkar, Prakash, P.  uhttps://library.ncl.res.in/content/highly-efficient-and-extremely-simple-protocol-oxidation-%CE%B1-hydroxyphosphonates-%CE%B101121nas a2200241   4500008004100000022001400041245011900055210006900174260000800243300001200251490000700263520028800270653001800558653002400576653002600600653001500626653001100641100002700652700002700679700001600706700002900722856012800751       2022                        eng d  a0019-510300aPotassium phosphate catalyzed highly efficient synthesis of structurally diverse thioethers at ambient temperature0 aPotassium phosphate catalyzed highly efficient synthesis of stru  cFEB  a154-1580 v613 a<p>
	Commercially available potassium phosphate has been demonstrated to be a highly efficient catalyst for the synthesis of thioethers employing two different routes viz. alkylation of thiols with alkyl/aralkyl halides and by Michael addition of thiols to conjugated alkenes.</p>
10aAlkyl halides10aPotassium phosphate10athia-Michael reaction10athioethers10athiols1 aMitragotri, Satish, D.1 aKulkarni, Makarand, A.1 aDesai, Uday1 aWadagaonkar, Prakash, P.  uhttps://library.ncl.res.in/content/potassium-phosphate-catalyzed-highly-efficient-synthesis-structurally-diverse-thioethers01595nas a2200217   4500008004100000022001400041245019500055210006900250300001400319520069500333653002401028653003001052653002001082653001901102100002701121700002501148700002601173700002701199700002901226856012201255       2023                        eng d  a1551-700400aCyclohexylamine -an efficient organocatalyst for the synthesis of 2-amino-4H-chromene derivatives by multicomponent reactions of salicylaldehydes, active methylene compounds and nitroalkanes0 aCyclohexylamine an efficient organocatalyst for the synthesis of  a2023121183 a<p>
	Cyclohexylamine was found to be an efficient organocatalyst for the synthesis of structurally diverse 2-amino4H-chromenes by multicomponent reaction of (substituted) salicylaldehydes, active methylene compounds and nitroalkanes at ambient temperature and under solvent-free conditions. The synthesis of a variety of 2amino-4H-chromenes was achieved using the reaction of (substituted) salicylaldehydes with two different C-H acids. The present protocol, which employed commercially available cyclohexylamine as an organocatalyst, offered the advantages of operational simplicity and avoidance of conventional purification methods and the obtained products were essentially pure.</p>
10a2-Amino-4H-chromene10aactive methylene compound10acyclohexylamine10aorganocatalyst1 aMitragotri, Satish, D.1 aKhyadage, Poonam, H.1 aChorghade, Diksha, S.1 aKulkarni, Makarand, A.1 aWadagaonkar, Prakash, P.  uhttps://library.ncl.res.in/content/cyclohexylamine-efficient-organocatalyst-synthesis-2-amino-4h-chromene-derivatives