01176nas a2200229   4500008004100000022001400041245006200055210005700117260010600174300001400280490000700294520039100301653001200692653002200704653002100726653001900747653002000766100002900786700001900815700001900834856009300853       2008                        eng d  a0040-403900aConcise synthesis of protected (2S,4R)-4-hydroxyornithine0 aConcise synthesis of protected 2S4R4hydroxyornithine  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcMAY  a3297-32990 v493 a<p>A short synthesis of the nonproteinogenic amino acid, (2S,4R)-4-hydroxyornithine is described. Starting from racemic benzyl glycidol, the scaffold of the target compound was constructed in high enantio- and diastereoselectivity using Jacobsen's hydrolytic kinetic resolution (HKR) and regioselective opening of an epoxide as key steps. (c) 2008 Elsevier Ltd. All rights reserved.</p>10aEpoxide10aGrignard reaction10ahydroxyornithine10aJacobsen's HKR10aNatural product1 aPandey, Satyendra, Kumar1 aPandey, Menaka1 aKumar, Pradeep  uhttps://library.ncl.res.in/content/concise-synthesis-protected-2s4r-4-hydroxyornithine-0