01840nas a2200181 4500008004100000022001400041245012700055210006900182260000800251300001600259490000700275520115400282100002201436700002801458700002401486700002001510856012801530 2021 eng d a1144-054600aAchiral and chiral NNN-pincer nickel complexes with oxazolinyl backbones: application in transfer hydrogenation of ketones0 aAchiral and chiral NNNpincer nickel complexes with oxazolinyl ba cJUL a11927-119360 v453 aWe describe the synthesis of new NNN-oxazolinyl-pincer nickel complexes and their application in the transfer hydrogenation of ketones. Achiral NNN-ligands, R `(2)-oxazolinyl-2-C6H4-NH-C(O)CH2NEt2 [((R ` 2-OxNNNEt2))-H; R' = H (3a), R ` = Me (3b)], and chiral ligands, (R)-R `-oxazolinyl-2-C6H4-NH-C(O)CH2NEt2 [(R)-((R `-OxNNNEt2))-H; R ` = Ph (3c), R ` = CH2Ph (3d), R ` = Pr-i (3e), R ` = (CH2Pr)-Pr-i (3f)], were efficiently synthesized. Treatment of these ligands with (DME)NiCl2 afforded the desired amido-pincer nickel complexes, ((R ` 2-OxNNNEt2))NiCl [R ` = H (4a), R ` = Me (4b)] and ((R `-OxNNNEt2))NiCl [R ` = Ph (4c), R ` = CH2Ph (4d), R ` = Pr-i (4e), R ` = (CH2Pr)-Pr-i (4f)], in good yields. All the ligand precursors and nickel complexes were thoroughly characterized by various analytical techniques. The molecular structures of 4a, 4d and 4f were established by X-ray crystallography. The developed nickel complexes were found to be efficient catalysts for the transfer hydrogenation of ketones using (PrOH)-Pr-i as a viable hydrogen source. Enantioselectivity in hydrogenation was not observed with the developed chiral catalysts.1 aJagtap, Rahul, A.1 aAnkade, Shidheshwar, B.1 aGonnade, Rajesh, G.1 aPunji, Benudhar uhttps://library.ncl.res.in/content/achiral-and-chiral-nnn-pincer-nickel-complexes-oxazolinyl-backbones-application-transfer01576nas a2200229 4500008004100000022001400041245011100055210006900166260000800235300001400243490000800257520078000265653002001045653002401065653001201089653001901101653003501120100001901155700002301174700002001197856012901217 2021 eng d a1615-415000aAdvances in C(sp(2))-H/C(sp(2))-H oxidative coupling of (Hetero)arenes using 3d transition metal catalysts0 aAdvances in Csp2HCsp2H oxidative coupling of Heteroarenes using  cAPR a1998-20220 v3633 a

C-H/C-H oxidative coupling has emerged as a straightforward and powerful technique for the construction of (hetero)biaryls, with substantial application to drug discovery, agrochemicals, biology, and material sciences. Mainly aryl-aryl, aryl-heteroaryl, and heteroaryl-heteroaryl couplings via double C(sp(2))-H activation using 4d or 5d noble transition metal catalysts have been extensively studied. Considering the earth-abundant and inexpensive nature of 3d transition metals, the sustainable development of C(sp(2))-H/C(sp(2))-H oxidative coupling employing such metal catalysts has gained significant attention. In this review, we present a comprehensive overview of C(sp(2))-H/C(sp(2))-H oxidative coupling of (hetero)arenes catalyzed by 3d transition metals.

10a(hetero)biaryls10a3d transition metal10aBiaryls10aC-H activation10across-dehydrogenative coupling1 aBansal, Sadhna1 aShabade, Anand, B.1 aPunji, Benudhar uhttps://library.ncl.res.in/content/advances-csp2-hcsp2-h-oxidative-coupling-heteroarenes-using-3d-transition-metal-catalysts01525nas a2200193 4500008004100000022001400041245007400055210006900129260000900198520088800207653001101095653001901106653002001125653001601145653002101161100002601182700002001208856010301228 2021 eng d a0039-788100aAdvances in transition-metal-catalyzed C-H bond oxygenation of amides0 aAdvances in transitionmetalcatalyzed CH bond oxygenation of amid cAPR 3 a

C-O bond formation represents a fundamental chemical transformation in organic synthesis to develop valuably oxygenated (hetero)arenes. Particularly, the direct and regioselective C-H bond oxygenation of privileged amides, using a transition metal catalyst and a mild oxygenating source, is a step-economy and attractive approach. During the last decade, considerable progress has been realized in the direct C-H oxygenation of primary, secondary, and tertiary amides. This Short Review compiles the advances in transition-metal-catalyzed oxygenation of C(sp(2))-H and C(sp(3))-H bonds on various amides with diverse oxygenation sources. The review is categorized into two different major sections: (i) C(sp(2))-H oxygenation and (ii) C(sp(3))-H oxygenation. Each section is discussed based on the directing group (monodentate and bidentate) attached to the amide derivatives.

10aAmides10aC-H activation10adirecting group10aOxygenation10aTransition Metal1 aVijaykumar, Muniyappa1 aPunji, Benudhar uhttps://library.ncl.res.in/content/advances-transition-metal-catalyzed-c-h-bond-oxygenation-amides01698nas a2200241 4500008004100000022001400041245007700055210006900132260000800201300001200209490000700221520098000228653001501208653001101223653002601234653001701260653001201277653000901289653001401298100002201312700002001334856010201354 2023 eng d a0936-521400aAdvances in the iron-catalyzed direct functionalizations of heterocycles0 aAdvances in the ironcatalyzed direct functionalizations of heter cAPR a683-6970 v343 a

Direct functionalization of heterocycles is an advanced strategy for diversifying privileged and biorelevant heterocycle-containing molecules. Particularly, use of the most abundant transition metal, iron, as a catalyst makes this process highly cost-effective and sustainable. Recently, some progress has been realized towards the direct functionalization of heterocycles under iron catalysis. Herein, we present the developments in the C-H bond functionalizations and related reactions of various heterocycles by abundant iron salts. This Synpacts is categorized into different sections based on heterocycles being functionalized, and each section is discussed based on the type of reaction catalyzed by iron. 1 Introduction 2 Functionalization of Indoles 2.1 Alkylation 2.2 Alkenylation 2.3 Other Reactions 3 Oxindoles and isatins 3.1 C-C Bond Formation 3.2 C-Heteroatom Bond Formation 4 Pyridines and Furans 5 Functionalization of Azoles 6 Summary and Outlook

10aAlkylation10aazoles10aC-H functionalization10aheterocycles10aindoles10airon10aMechanism1 aPradhan, Chandini1 aPunji, Benudhar uhttps://library.ncl.res.in/content/advances-iron-catalyzed-direct-functionalizations-heterocycles01814nas a2200157 4500008004100000022001400041245011400055210006900169260000900238300001400247490000700261520121600268100002201484700002001506856013001526 2024 eng d a2052-412900aAdvancement in the C-H bond alkylation of (hetero)arenes catalyzed by the most abundant transition metal-iron0 aAdvancement in the CH bond alkylation of heteroarenes catalyzed  cAPR  a2397-24170 v113 a

Alkylation reaction stands as a crucial organic transformation, fostering privileged alkylated arenes and heteroarenes in molecular science. Over the past decade, the utilization of the most abundant transition metal iron for regioselective C-H bond alkylation has gained substantial prominence, offering a straightforward and sustainable approach. Noteworthy progress has been achieved in the alkylation of diverse arenes and heteroarenes involving primary, secondary, and tertiary alkyl (pseudo)halide, alkene, and alcohol coupling partners via both the mono- and bidentate-chelate strategies. This concise and focused review provides an overview of the advancement in the iron-catalyzed alkylation of arenes and heteroarenes through step-economical C-H functionalization, their novel features, proposed mechanisms, and future research directions. The review is categorized into two major sections: (i) alkylation of arenes and (ii) alkylation of heteroarenes. Each section is discussed based on the class of arenes and heteroarenes used. Advancement in the direct C-H bond alkylation of arenes and heteroarenes using the catalysts based on the most abundant transition metal, iron, is summarized.

1 aPradhan, Chandini1 aPunji, Benudhar uhttps://library.ncl.res.in/content/advancement-c-h-bond-alkylation-heteroarenes-catalyzed-most-abundant-transition-metal-iron01202nas a2200157 4500008004100000022001400041245010100055210006900156260000800225300001200233490000700245520062400252100002200876700002000898856012600918 2025 eng d a2374-794300aAtroposelective construction of biaryls enabled by a Ni(II)-catalyzed aerobic oxidation strategy0 aAtroposelective construction of biaryls enabled by a NiIIcatalyz cFEB a187-1890 v113 a

Enantioriched biaryls synthesis via aerobic oxidative cross-coupling of arenes involving bioinspired oxygen activation by Ni(II).

1 aPradhan, Chandini1 aPunji, Benudhar uhttps://library.ncl.res.in/content/atroposelective-construction-biaryls-enabled-niii-catalyzed-aerobic-oxidation-strategy