01998nas a2200349 4500008004100000022001400041245022500055210006900280260000900349300001500358490000700373520077700380653002301157653001201180653001601192653002201208653002601230653001301256100002301269700001501292700002001307700001901327700001701346700002701363700002201390700002301412700002301435700001801458700002501476700002101501856012601522 2022 eng d a0947-653900aInterplay of anion-pi(+) and pi(+)-pi(+) interactions in novel pyrido[2,1-a]isoquinolinium-based aiegens - substituent- and counterion-dependent fluorescence modulation and applications in live cell mitochondrial imaging0 aInterplay of anionpi and pipi interactions in novel pyrido21aiso cJUL  ae2022006320 v283 a

Recently, the concept of anion-pi(+) interactions has witnessed unique applications in the field of AIEgen development. In this contribution, we disclose a consolidated study of a library of N-doped ionic AIEgens accessed through silver-mediated cyclization of pyridino-alkynes. A thorough photophysical, computational and crystallographic study has been conducted to rationalize the observed substituent- and counterion-dependent fluorescence properties of these luminogens. We further elucidate the prominent role of anion-pi(+) interactions, pi(+)-pi(+) interactions and other non-covalent interactions, in inhibiting the undesired ACQ effect. Finally, we have also demonstrated the application of selected AIEgens for imaging of mitochondria in live cells.

10a1-a]isoquinolinium10aAIEgens10aanion-pi(+)10acrystal structure10amitochondrial imaging10apyrido[21 aMule, Ravindra, D.1 aRoy, Rupam1 aMandal, Koushik1 aChopra, Deepak1 aDutta, Tanoy1 aSancheti, Shashank, P.1 aShinde, Popat, S.1 aBanerjee, Somsuvra1 aKoner, Apurba, Lal1 aBhowal, Rohit1 aSenthilkumar, Beeran1 aPatil, Nitin, T. uhttps://library.ncl.res.in/content/interplay-anion-pi-and-pi-pi-interactions-novel-pyrido21-aisoquinolinium-based-aiegens