01698nas a2200241 4500008004100000022001400041245007700055210006900132260000800201300001200209490000700221520098000228653001501208653001101223653002601234653001701260653001201277653000901289653001401298100002201312700002001334856010201354 2023 eng d a0936-521400aAdvances in the iron-catalyzed direct functionalizations of heterocycles0 aAdvances in the ironcatalyzed direct functionalizations of heter cAPR a683-6970 v343 a

Direct functionalization of heterocycles is an advanced strategy for diversifying privileged and biorelevant heterocycle-containing molecules. Particularly, use of the most abundant transition metal, iron, as a catalyst makes this process highly cost-effective and sustainable. Recently, some progress has been realized towards the direct functionalization of heterocycles under iron catalysis. Herein, we present the developments in the C-H bond functionalizations and related reactions of various heterocycles by abundant iron salts. This Synpacts is categorized into different sections based on heterocycles being functionalized, and each section is discussed based on the type of reaction catalyzed by iron. 1 Introduction 2 Functionalization of Indoles 2.1 Alkylation 2.2 Alkenylation 2.3 Other Reactions 3 Oxindoles and isatins 3.1 C-C Bond Formation 3.2 C-Heteroatom Bond Formation 4 Pyridines and Furans 5 Functionalization of Azoles 6 Summary and Outlook

10aAlkylation10aazoles10aC-H functionalization10aheterocycles10aindoles10airon10aMechanism1 aPradhan, Chandini1 aPunji, Benudhar uhttps://library.ncl.res.in/content/advances-iron-catalyzed-direct-functionalizations-heterocycles01814nas a2200157 4500008004100000022001400041245011400055210006900169260000900238300001400247490000700261520121600268100002201484700002001506856013001526 2024 eng d a2052-412900aAdvancement in the C-H bond alkylation of (hetero)arenes catalyzed by the most abundant transition metal-iron0 aAdvancement in the CH bond alkylation of heteroarenes catalyzed  cAPR  a2397-24170 v113 a

Alkylation reaction stands as a crucial organic transformation, fostering privileged alkylated arenes and heteroarenes in molecular science. Over the past decade, the utilization of the most abundant transition metal iron for regioselective C-H bond alkylation has gained substantial prominence, offering a straightforward and sustainable approach. Noteworthy progress has been achieved in the alkylation of diverse arenes and heteroarenes involving primary, secondary, and tertiary alkyl (pseudo)halide, alkene, and alcohol coupling partners via both the mono- and bidentate-chelate strategies. This concise and focused review provides an overview of the advancement in the iron-catalyzed alkylation of arenes and heteroarenes through step-economical C-H functionalization, their novel features, proposed mechanisms, and future research directions. The review is categorized into two major sections: (i) alkylation of arenes and (ii) alkylation of heteroarenes. Each section is discussed based on the class of arenes and heteroarenes used. Advancement in the direct C-H bond alkylation of arenes and heteroarenes using the catalysts based on the most abundant transition metal, iron, is summarized.

1 aPradhan, Chandini1 aPunji, Benudhar uhttps://library.ncl.res.in/content/advancement-c-h-bond-alkylation-heteroarenes-catalyzed-most-abundant-transition-metal-iron01202nas a2200157 4500008004100000022001400041245010100055210006900156260000800225300001200233490000700245520062400252100002200876700002000898856012600918 2025 eng d a2374-794300aAtroposelective construction of biaryls enabled by a Ni(II)-catalyzed aerobic oxidation strategy0 aAtroposelective construction of biaryls enabled by a NiIIcatalyz cFEB a187-1890 v113 a

Enantioriched biaryls synthesis via aerobic oxidative cross-coupling of arenes involving bioinspired oxygen activation by Ni(II).

1 aPradhan, Chandini1 aPunji, Benudhar uhttps://library.ncl.res.in/content/atroposelective-construction-biaryls-enabled-niii-catalyzed-aerobic-oxidation-strategy