01932nas a2200229 4500008004100000022001400041245012600055210006900181260011000250300001400360490000600374520101600380100002701396700002201423700002401445700002201469700002401491700002301515700001801538700002501556856012101581 2015 eng d a2050-750X00aCalcium phosphate nanocapsule crowned multiwalled carbon nanotubes for pH triggered intracellular anticancer drug release0 aCalcium phosphate nanocapsule crowned multiwalled carbon nanotub aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcAPR a3931-39390 v33 a

We report calcium phosphate (CaP) nanocapsule crowned multi-walled carbon nanotubes (CNT-GSH-G4-CaP) as a novel platform for intracellular delivery of an anticancer drug. As a proof-of-concept, CNT-GSH-G4-CaP demonstrates release of anticancer drug doxorubicin hydrochloride (DOX) within intracellular lysosomes from the interior cavity of CNT upon pH triggered CaP dissolution. Importantly, we found that the CNT with a CaP nanolid can efficiently prevent untimely drug release at physiological pH but promotes DOX release at increased acidic milieu as observed in subcellular compartments such as lysosomes (similar to 5.0). This ``zero premature release'' characteristic is of clinical significance in delivering cytotoxic drugs, by reducing systemic toxicity and thus beneficial for the effective anticancer treatment. We envision that this pH triggered CaP crowned CNT nanosystem would lead to a new generation of self-regulated platforms for intracellular delivery of a variety of anticancer drugs.

1 aBanerjee, Shashwat, S.1 aTodkar, Kiran, J.1 aKhutale, Ganesh, V.1 aChate, Govind, P.1 aBiradar, Ankush, V.1 aGawande, Manoj, B.1 aZboril, Radek1 aKhandare, Jayant, J. uhttps://library.ncl.res.in/content/calcium-phosphate-nanocapsule-crowned-multiwalled-carbon-nanotubes-ph-triggered-001763nas a2200229 4500008004100000022001400041245009100055210006900146260011000215300001400325490000700339520089200346100002301238700002301261700002001284700001801304700002401322700002101346700001801367700002401385856012401409 2015 eng d a0306-001200aCore-shell nanoparticles: synthesis and applications in catalysis and electrocatalysis0 aCoreshell nanoparticles synthesis and applications in catalysis  aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcAUG a7540-75900 v443 a

Core-shell nanoparticles (CSNs) are a class of nanostructured materials that have recently received increased attention owing to their interesting properties and broad range of applications in catalysis, biology, materials chemistry and sensors. By rationally tuning the cores as well as the shells of such materials, a range of core-shell nanoparticles can be produced with tailorable properties that can play important roles in various catalytic processes and offer sustainable solutions to current energy problems. Various synthetic methods for preparing different classes of CSNs, including the Stober method, solvothermal method, one-pot synthetic method involving surfactants, etc., are briefly mentioned here. The roles of various classes of CSNs are exemplified for both catalytic and electrocatalytic applications, including oxidation, reduction, coupling reactions, etc.

1 aGawande, Manoj, B.1 aGoswami, Anandarup1 aAsefa, Tewodros1 aGuo, Huizhang1 aBiradar, Ankush, V.1 aPeng, Dong-Liang1 aZboril, Radek1 aVarma, Rajender, S. uhttps://library.ncl.res.in/content/core-shell-nanoparticles-synthesis-and-applications-catalysis-and-electrocatalysis-001871nas a2200193 4500008004100000022001400041245013000055210006900185260011000254300001200364490000700376520105800383100002301441700002301464700002201487700002301509700001801532856012701550 2015 eng d a1463-926200aHeterogeneously catalyzed strategies for the deconstruction of high density polyethylene: plastic waste valorisation to fuels0 aHeterogeneously catalyzed strategies for the deconstruction of h aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcOCT a146-1560 v173 a

The plastic industry generates enormous quantities of plastics at projected rates (both production and consumption) which can significantly threaten our environment in terms of plastic waste generation. High density polyethylene (HDPE) is one of the main fractions of municipal solid waste which has a remarkable potential to be valorised into fuels (e.g. bio-oils). Catalytic degradation is an innovative alternative process to transform plastic waste into such value added products. This mini review was aimed to discuss the most relevant and recent catalysts developed for the catalytic degradation of HDPE including metal oxides, sulphated metal oxides, zeolites, nanostructured zeolites, molecular sieves, fluid catalytic cracking (FCC) catalysts, metal carbonates and mesoporous materials for the production of chemicals and fuels (e.g. diesel and gasolines). Activities and selectivities as well as important effects of additives, particle size, catalyst to polymer ratios and also recent approaches for waste management will be discussed.

1 aBurange, Anand, S.1 aGawande, Manoj, B.1 aLam, Frank, L. Y.1 aJayaram, Radha, V.1 aLuque, Rafael uhttps://library.ncl.res.in/content/heterogeneously-catalyzed-strategies-deconstruction-high-density-polyethylene-plastic-001796nas a2200253 4500008004100000022001400041245013300055210006900188260000800257300001200265490000600277520091200283653002401195653001601219653002801235653002701263653000901290100002401299700002801323700002301351700001701374700002401391856012701415 2017 eng d a2168-048500aEnvironmentally benign bioderived carbon microspheres-supported molybdena nanoparticles as catalyst for the epoxidation reaction0 aEnvironmentally benign bioderived carbon microspheressupported m cJAN a904-9100 v53 a

A one pot synthesis of molybdenum oxide nanoparticles (NPs supported on bioderived carbon microspheres is reported. The catalyst was synthesized by the low temperature hydrothermal (LTH) method using D-glucose and bagasse as the carbon source. The carbonization of bagasse resulted in the formation of nonuniform carbon microspheres while glucose resulted in uniform carbon spheres. SEM and STEM elemental mapping show the uniform distribution of molybdenum oxide NPs over the carbon microspheres. XPS spectroscopy confirmed that molybdenum was in the Mo6+ oxidation state. The 1% MoO3 supported on carbon microspheres derived from D-glucose showed excellent catalytic activity up to 100% olefin conversion with 100% epoxide selectivity using organic tent-butyl hydroperoxide as an oxidant. The catalyst was successfully used for up to five cycles without losing substantial activity and selectivity.

10aCarbon microspheres10aepoxidation10aheterogeneous catalysis10aHydrothermal synthesis10aTBHP1 aDoke, Dhananjay, S.1 aUmbarkar, Shubhangi, B.1 aGawande, Manoj, B.1 aZbori, Radek1 aBiradar, Ankush, V. uhttps://library.ncl.res.in/content/environmentally-benign-bioderived-carbon-microspheres-supported-molybdena-nanoparticles