01825nas a2200205   4500008004100000022001400041245011600055210006900171260000800240300001200248490000700260520109500267653003001362653002201392653002101414653003001435100001901465700000501484856013001489       2021                        eng d  a0934-086600aAmphifunctional mesoporous silica nanoparticles with ``molecular gates'' for controlled drug uptake and release0 aAmphifunctional mesoporous silica nanoparticles with molecular g  cDEC  a21001850 v383 aIt is demonstrated that the uptake and release of hydrophobic drugs/dyes by mesoporous silica nanoparticles (MSN) is critically dependent on the functional groups present on their outer surfaces. For this, amphifunctional MSNs are synthesized, possessing hydrophobic pores and hydrophilic functional groups on the outer surface. Further, the outer surface is modified with a different chain length of molecules, e.g., propargyl alcohol, triethylene glycol, and PEG (2000) via azide-alkyne click chemistry. The effect of these different surface functional groups on uptake of drug/dye is demonstrated with Nile red, proflavine (free base form), and rhodamine 6G. The uptake of these molecules is found to be inversely proportional to the bulkiness of surface functionality. To counter this effect, an alternate method of loading is proposed and demonstrated. Finally, the effect of these different functional groups on the release of loaded drug proflavine is studied, which supports the hypothesis that bulkier outer surface groups also hinder the release of drugs loaded in the porous MSN.10adrug delivery and release10aMesoporous silica10amolecular gating10asurface functionalization1 aShinde, Pravin1 a  uhttps://library.ncl.res.in/content/amphifunctional-mesoporous-silica-nanoparticles-molecular-gates-controlled-drug-uptake-and02173nas a2200217   4500008004100000022001400041245017900055210006900234260000800303300001200311490000600323520133800329653004101667653002401708653002901732100001801761700002301779700001801802700000501820856013001825       2021                        eng d  a2196-735000aLamellar bimetallic thiolates: synthesis, characterization, and their utilization for the preparation of bimetallic chalcogenide nanocrystals through mechanochemical grinding0 aLamellar bimetallic thiolates synthesis characterization and the  cDEC  a21008980 v83 aThiolates of single metal ions are known to exist as lamellar structures in the neat state and some of these metal thiolates can be delaminated into individual molecular sheets simply by adding a nonpolar organic solvent. It is established here that even bimetallic thiolates such as copper-indium thiolate and silver-indium thiolate exist as lamellar sheets. Each of these sheets consists of both metal ions arranged in a random fashion. It is also demonstrated that these bimetallic thiolates can be employed as single source precursors to prepare phase pure bimetallic chalcogenide nanocrystals (NCs) through mechanochemical routes by grinding them with an appropriate chalcogenide source. Notably, these bimetallic chalcogenide NCs, though synthesized in the absence of any solvent, get easily dispersed in nonpolar solvents as their surface is protected by the thiolate molecules released during the grinding process. These ternary NCs display a strong and tunable photoluminescence in the visible to near-infrared region. Based on detailed systematic studies it is concluded that to obtain phase pure bimetallic sulfide/selenide NCs bimetallic thiolates, consisting of both metal ions in each sheet, must be used as single source precursors and physical mixtures of individual thiolates do not afford such phase pure materials.10abimetallic chalcogenide nanocrystals10abimetallic thiolate10amechanochemical grinding1 aBera, Abhijit1 aPathak, Sushil, S.1 aKotha, Vishal1 a  uhttps://library.ncl.res.in/content/lamellar-bimetallic-thiolates-synthesis-characterization-and-their-utilization-preparation01217nas a2200205   4500008004100000022001400041245007500055210006900130260000800199300000800207490000800215520061300223100000500836700003600841700002000877700000500897700000500902700000500907856009900912       2021                        eng d  a0974-362600aSynthesis of anisotropic rod-like gold nanostructures in organic media0 aSynthesis of anisotropic rodlike gold nanostructures in organic   cDEC  a1060 v1333 aSynthesis of anisotropic rod-like gold nanostructures was carried out in chloroform employing a modified ascorbic acid derivative as a reducing agent in the presence and absence of seed particles. The seed particles and/or the chloroaurate ions were phase transferred to the organic media using n-octadecyl amine. High-resolution transmission electron microscopy analysis clearly revealed that the anisotropic structures are single crystalline in nature. The stabilization of certain crystallographic faces of anisotropic gold nanostructures by amines is invoked to explain the formation of these structures.1 a1 aSivasankaran, Prathap, Chandran1 aPatel, Pitambar1 a1 a1 a  uhttps://library.ncl.res.in/content/synthesis-anisotropic-rod-gold-nanostructures-organic-media