01568nas a2200265   4500008004100000022001400041245007600055210006900131260007400200300001200274490000700286520066600293653002000959653002100979653002201000653002501022100001601047700002901063700001901092700002601111700001901137700001701156700002601173856010301199       2007                        eng d  a0141-549200aNitrate reductase-mediated synthesis of silver nanoparticles from AgNO30 aNitrate reductasemediated synthesis of silver nanoparticles from  aVAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDSbSPRINGERcMAR  a439-4450 v293 a<p>Synthesis of silver nanoparticles using alpha-NADPH-dependent nitrate reductase and phytochelatin in vitro has been demonstrated for the first time. The silver ions were reduced in the presence of nitrate reductase, leading to the formation of a stable silver hydrosol 10-25 nm diam. and stabilized by the capping peptide. The nanoparticles were characterized by X-ray diffraction, transmission electron microscopy, X-ray photoelectron spectroscopy and UV-Vis absorption. These studies will help in designing a rational enzymatic strategy for the synthesis of nanomaterials of different chemical composition, shapes and sizes as well as their separation.</p>10aCapping Peptide10aenzymatic method10anitrate reductase10asilver nanoparticles1 aKumar, Anil1 aAbyaneh, Majid, Kazemian1 aGosavi, S., W.1 aKulkarni, Sulabha, K.1 aPasricha, Renu1 aAhmad, Absar1 aKhan, Mohammad, Islam  uhttps://library.ncl.res.in/content/nitrate-reductase-mediated-synthesis-silver-nanoparticles-agno302613nas a2200205   4500008004100000245012300041210006900164260000800233300001400241490000700255520185100262100002702113700002302140700001902163700002302182700001702205700002902222700002502251856013102276       2016                        eng d00aNevirapine loaded core shell gold nanoparticles by double emulsion solvent evaporation: invitro and in vivo evaluation0 aNevirapine loaded core shell gold nanoparticles by double emulsi  cJAN  a1071-10830 v133 aBackground: HIV/AIDS is a macrophage resident infection localized in the reticuloendothelial system and remote locations of brain and bone marrow. We present core shell nanoparticles of gold(AuNPs) and nevirapine(NVP) for targeted delivery to the multiple HIV reservoirs. The aim of the study was to design core shell NVP loaded AuNPs with high drug loading and to evaluate biodistribution of the nanoparticles in possible HIV reservoirs in vivo. A specific objective was to assess the possible synergy of AuNPs with NVP on anti-HIV activity in vitro. 

Method: Core shell nanoparticles were prepared by double emulsion solvent evaporation method and characterized. 

Results: Glyceryl monostearate-nevirapine-gold nanoparticles(GMS-NVP-AuNPs) revealed high entrapment efficiency (> 70%), high loading (similar to 40%), particle size < 250 nm and zeta potential -35.9 +/- 1.41mv and exhibited sustained release with good stability. Surface plasmon resonance indicated shell formation while SEM coupled EDAX confirmed the presence of Au. TEM confirmed formation of spherical core shell nanoparticles. GMS-NVP-AuNPs revealed low hemolysis (< 10 %) and serum stability upto 6 h. GMS-NVP-AuNPs exhibited rapid, high and sustained accumulation in the possible HIV reservoir organs, including the major organs of liver, spleen, lymph nodes, thymus and also remote locations of brain, ovary and bone marrow. High cell viability and enhanced uptake in PBMC's and TZM-bl cells were observed. While uptake in PBMC's proposed monocytes/macrophages enabled brain delivery. GMS-NVP-AuNPs demonstrated synergistic anti-HIV activity. 

Conclusion: The superior anti-HIV activity in vitro coupled with extensive localization of the nanoparticles in multiple HIV reservoirs suggests great promise of the core shell GMS-NVP-AuNPs for improved therapy of HIV.1 aDalvi, Bhagyashree, R.1 aSiddiqui, Ejaz, A.1 aSyed, Asad, S.1 aVelhal, Shilpa, M.1 aAhmad, Absar1 aBandivdekar, Atmaram, B.1 aDevarajan, Padma, V.  uhttps://library.ncl.res.in/content/nevirapine-loaded-core-shell-gold-nanoparticles-double-emulsion-solvent-evaporation-invitro01874nas a2200181   4500008004100000245011400041210006900155260000800224300001400232490000600246520121400252100001701466700001801483700001701501700002301518700002501541856012601566       2017                        eng d00aNanotubular hard carbon derived from renewable natural seed gel for high performance sodium-ion battery anode0 aNanotubular hard carbon derived from renewable natural seed gel   cAUG  a6909-69150 v23 a<p>Electrical energy storage devices such as batteries and supercapacitors are perhaps the most researched topic today in view of its critical implications for the successful implementations of various renewable energy harvesting initiatives. Amongst the various battery systems being currently examined, the Li-battery continues to be a main player, but the Na-ion battery has been attracting significant attention lately due to the concerns about the limited reserves and high cost of Li. Hard carbon is recognized to be a good anode material for Na-battery. In this work we present a novel approach to synthesize such hard carbon from a natural gel derived from the commonly used Basil seeds (Osimum Basilicum) which swell 30 times their weight by absorbing water. The hard carbon obtained by pyrolysis of the freeze-dried mucilage possesses sheet-like and tubular morphology with decorated surface defects attributed to the presence of oxygen functionalities. This hard carbon shows a good reversible capacity of 195 mAh g(-1) at 0.1A g(-1) with an impressive approximate to 91% retention of initial capacity after 300 cycles and sustains high current densities with not much change in capacity value.</p>1 aSharma, Neha1 aGawli, Yogesh1 aAhmad, Absar1 aMuhammed, Musthafa1 aOgale, Satishchandra  uhttps://library.ncl.res.in/content/nanotubular-hard-carbon-derived-renewable-natural-seed-gel-high-performance-sodium-ion