02122nas a2200253   4500008004100000022001400041245013700055210006900192260000800261300001400269490000700283520120200290653001801492653002101510653002501531653002601556653002801582100002601610700002201636700002401658700002901682700002601711856013101737       2021                        eng d  a0922-616800aSolvent free, environment benign synthesis of 1,4-dihydropyridines and polyhydroquinolines by using heterogeneous Zn/MCM-41 catalyst0 aSolvent free environment benign synthesis of 14dihydropyridines   cAUG  a3263-32870 v473 a<p>Heterogeneous catalysis has been utilized in number of efficient reactions with higher selectivity of the product, more stable, reusable and easy for separation as compared to homogeneous catalysts. Generally, heterogeneous catalysts are prepared by using mesoporous materials, microporous materials, metal oxides and metal organic framework. The mesoporous materials have small particle size and high surface area as compared to the microporous materials. The adsorbent mesoporous materials have highly efficient for the therapeutic applications in chemistry hence it has best as compared to other heterogeneous materials. Herein, we have reported synthesis of 1,4-dihydropyridines and polyhydroquinolines at solvent free and environmental benign condition in the presence of Zn/MCM-41 catalyst. The present protocol gives excellent yield (89-96%) of the product within short reaction time by easy work up procedure and no need of further purification of product. The catalyst was characterized by XRD diffractometer, SEM, EDAX, TGA-DTA, BET surface area analysis and FT-IR Spectroscopy. The synthesized organic compounds were characterized by FT-IR, H-1 NMR, C-13 NMR, LC-MS spectrometry.</p>10aHigh activity10aHigh selectivity10amesoporous materials10amicroporous materials10aReusability of catalyst1 aDhengale, Shankar, D.1 aNaik, Vaibhav, M.1 aKolekar, Govind, B.1 aRode, Chandrashekhar, V.1 aAnbhule, Prashant, V.  uhttps://library.ncl.res.in/content/solvent-free-environment-benign-synthesis-14-dihydropyridines-and-polyhydroquinolines-using