01127nas a2200169   4500008004100000022001400041245009900055210006900154260010600223300001200329490000700341520041900348100002300767700002200790700001900812856012600831       2011                        eng d  a0957-416600aChemoenzymatic total synthesis of potent HIV RNase H inhibitor (-)-1,3,4,5-tetragalloylapiitol0 aChemoenzymatic total synthesis of potent HIV RNase H inhibitor 1  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcJAN  a173-1770 v223 a<p>Starting from racemic dimethyl 2-acetoxy-3-methylenesuccinate, the chemoenzymatic facile total synthesis of (-)-1,3,4,5-tetragalloylapiitol has been demonstrated via an efficient lipase catalyzed resolution followed by a DIBAL reduction-double gallyolation, osmium tetroxide dihydroxylation-double gallyolation, and reductive global O-benzyl deprotection pathway. (C) 2010 Elsevier Ltd. All rights reserved.</p>1 aBatwal, Ramesh, U.1 aPatel, Ramesh, M.1 aArgade, N., P.  uhttps://library.ncl.res.in/content/chemoenzymatic-total-synthesis-potent-hiv-rnase-h-inhibitor-1345-tetragalloylapiitol-001499nas a2200157   4500008004100000022001400041245012500055210006900180260011000249300001600359490000700375520078700382100002301169700001901192856013001211       2015                        eng d  a1477-052000aChemoenzymatic collective synthesis of optically active hydroxyl(methyl)tetrahydronaphthalene-based bioactive terpenoids0 aChemoenzymatic collective synthesis of optically active hydroxyl  aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcSEP  a11331-113400 v133 a<p>Starting from succinic anhydride and 2-methylanisole, a chemoenzymatic collective formal/total synthesis of several optically active tetrahydronaphthalene based bioactive natural products has been presented via advanced level common precursors; the natural product and antipode (-)/(+)-aristelegone B. Regioselective benzylic oxidations, stereoselective introduction of hydroxyl groups at the alpha-position of ketone moiety in syn-orientation, efficient enzymatic resolutions with high enantiomeric purity, stereoselective reductions, samarium iodide induced deoxygenations and tandem acylation-Wittig reactions without racemization and/or eliminative aromatization were the key features. An attempted diastereo-selective synthesis of (+/-)-vallapin has also been described.</p>1 aBatwal, Ramesh, U.1 aArgade, N., P.  uhttps://library.ncl.res.in/content/chemoenzymatic-collective-synthesis-optically-active-hydroxylmethyltetrahydronaphthalene-001440nas a2200241   4500008004100000022001400041245017500055210006900230260007500299300001400374490000700388520045500395653002000850653002500870653002300895653005000918653002500968653002100993653001401014100002301028700001901051856012801070       2016                        eng d  a0039-788100aChemoenzymatic access to (+)-artabotriol and its application in collective synthesis of (+)-grandiamide D, (-)-tulipalin B, (+)-spirathundiol, and (+)-artabotriolcaffeate0 aChemoenzymatic access to artabotriol and its application in coll  aRUDIGERSTR 14, D-70469 STUTTGART, GERMANYbGEORG THIEME VERLAG KGcJUL  a2130-21360 v483 a<p>Starting from dimethyl (+/-)-2-hydroxy-3-methylenesuccinnate chemoenzymatic collective formal/total synthesis of enantiomerically pure bioactive natural products has been described via the advanced level common precursor (+)-artabotriol. An efficient enzymatic resolution with high enantiomeric purity, selective diester to diol reduction, and requisite dehydrative coupling reactions without any racemization are the significant topographies.</p>10a(+)-artabotriol10acollective synthesis10acoupling reactions10adimethyl (+/-)-2-hydroxy-3-methylenesuccinate10aEnzymatic resolution10aNatural products10areduction1 aBatwal, Ramesh, U.1 aArgade, N., P.  uhttps://library.ncl.res.in/content/chemoenzymatic-access-artabotriol-and-its-application-collective-synthesis-grandiamide-d