01127nas a2200169   4500008004100000022001400041245009900055210006900154260010600223300001200329490000700341520041900348100002300767700002200790700001900812856012600831       2011                        eng d  a0957-416600aChemoenzymatic total synthesis of potent HIV RNase H inhibitor (-)-1,3,4,5-tetragalloylapiitol0 aChemoenzymatic total synthesis of potent HIV RNase H inhibitor 1  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcJAN  a173-1770 v223 a<p>Starting from racemic dimethyl 2-acetoxy-3-methylenesuccinate, the chemoenzymatic facile total synthesis of (-)-1,3,4,5-tetragalloylapiitol has been demonstrated via an efficient lipase catalyzed resolution followed by a DIBAL reduction-double gallyolation, osmium tetroxide dihydroxylation-double gallyolation, and reductive global O-benzyl deprotection pathway. (C) 2010 Elsevier Ltd. All rights reserved.</p>1 aBatwal, Ramesh, U.1 aPatel, Ramesh, M.1 aArgade, N., P.  uhttps://library.ncl.res.in/content/chemoenzymatic-total-synthesis-potent-hiv-rnase-h-inhibitor-1345-tetragalloylapiitol-001328nas a2200217   4500008004100000022001400041245010100055210006900156260007500225300001400300490000700314520048900321653003500810653001300845653003600858653002900894653001400923100002300937700001900960856013100979       2013                        eng d  a0039-788100aBiology-orientated synthesis of putrescine bisamides gigantamide A, dasyclamide, and cucullamide0 aBiologyorientated synthesis of putrescine bisamides gigantamide   aRUDIGERSTR 14, D-70469 STUTTGART, GERMANYbGEORG THIEME VERLAG KGcOCT  a2888-28920 v453 a<p>Starting from putrescine and the requisite carboxylic acids, first syntheses of bioactive natural products gigantamide A, dasyclamide, and cucullamide were accomplished in very good overall yields using an appropriate sequence of dehydrative coupling reactions. The syntheses of the corresponding dehomo analogues of these natural products are also described. Regioselective diisobutylaluminum hydride reduction of an unhindered carbonyl group in citraconimide is the key step.</p>10adehydrative coupling reactions10adiamines10anatural and unnatural bisamides10aregioselective reduction10asynthesis1 aBatwal, Ramesh, U.1 aArgade, N., P.  uhttps://library.ncl.res.in/content/biology-orientated-synthesis-putrescine-bisamides-gigantamide-dasyclamide-and-cucullamide-001499nas a2200157   4500008004100000022001400041245012500055210006900180260011000249300001600359490000700375520078700382100002301169700001901192856013001211       2015                        eng d  a1477-052000aChemoenzymatic collective synthesis of optically active hydroxyl(methyl)tetrahydronaphthalene-based bioactive terpenoids0 aChemoenzymatic collective synthesis of optically active hydroxyl  aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcSEP  a11331-113400 v133 a<p>Starting from succinic anhydride and 2-methylanisole, a chemoenzymatic collective formal/total synthesis of several optically active tetrahydronaphthalene based bioactive natural products has been presented via advanced level common precursors; the natural product and antipode (-)/(+)-aristelegone B. Regioselective benzylic oxidations, stereoselective introduction of hydroxyl groups at the alpha-position of ketone moiety in syn-orientation, efficient enzymatic resolutions with high enantiomeric purity, stereoselective reductions, samarium iodide induced deoxygenations and tandem acylation-Wittig reactions without racemization and/or eliminative aromatization were the key features. An attempted diastereo-selective synthesis of (+/-)-vallapin has also been described.</p>1 aBatwal, Ramesh, U.1 aArgade, N., P.  uhttps://library.ncl.res.in/content/chemoenzymatic-collective-synthesis-optically-active-hydroxylmethyltetrahydronaphthalene-000834nas a2200229   4500008004100000022001400041245003400055210003400089260007500123300001200198490000700210520017100217653001500388653001300403653002100416653001400437653002100451100002400472700002300496700001900519856006600538       2015                        eng d  a0039-788100aSynthesis of yangjinhualine A0 aSynthesis of yangjinhualine A  aRUDIGERSTR 14, D-70469 STUTTGART, GERMANYbGEORG THIEME VERLAG KGcFEB  a485-4880 v473 a<p>Selective reduction of 3-(4-hydroxyphenyl)-2-methylmaleic anhydride provides access the corresponding gamma-hydroxybutenolide natural product yangjinhualine A.</p>10aanhydrides10alactones10aNatural products10areduction10aRegioselectivity1 aDeore, Prashant, S.1 aBatwal, Ramesh, U.1 aArgade, N., P.  uhttps://library.ncl.res.in/content/synthesis-yangjinhualine-001440nas a2200241   4500008004100000022001400041245017500055210006900230260007500299300001400374490000700388520045500395653002000850653002500870653002300895653005000918653002500968653002100993653001401014100002301028700001901051856012801070       2016                        eng d  a0039-788100aChemoenzymatic access to (+)-artabotriol and its application in collective synthesis of (+)-grandiamide D, (-)-tulipalin B, (+)-spirathundiol, and (+)-artabotriolcaffeate0 aChemoenzymatic access to artabotriol and its application in coll  aRUDIGERSTR 14, D-70469 STUTTGART, GERMANYbGEORG THIEME VERLAG KGcJUL  a2130-21360 v483 a<p>Starting from dimethyl (+/-)-2-hydroxy-3-methylenesuccinnate chemoenzymatic collective formal/total synthesis of enantiomerically pure bioactive natural products has been described via the advanced level common precursor (+)-artabotriol. An efficient enzymatic resolution with high enantiomeric purity, selective diester to diol reduction, and requisite dehydrative coupling reactions without any racemization are the significant topographies.</p>10a(+)-artabotriol10acollective synthesis10acoupling reactions10adimethyl (+/-)-2-hydroxy-3-methylenesuccinate10aEnzymatic resolution10aNatural products10areduction1 aBatwal, Ramesh, U.1 aArgade, N., P.  uhttps://library.ncl.res.in/content/chemoenzymatic-access-artabotriol-and-its-application-collective-synthesis-grandiamide-d