01340nas a2200253   4500008004100000022001400041245013000055210006900185260007700254300001400331520038900345653001700734653001300751653002600764653001400790653002200804100002500826700001700851700002400868700002100892700002400913700002100937856012800958       2014                        eng d  a1434-193X00aGeneral approach to N-heterocyclic carbenes with a fused tetracyclic core: ligands for suzuki-miyaura cross-coupling reaction0 aGeneral approach to Nheterocyclic carbenes with a fused tetracyc  aBOSCHSTRASSE 12, D-69469 WEINHEIM, GERMANYbWILEY-V C H VERLAG GMBHcJUL  a4482-44863 a<p>The synthesis of an N-heterocyclic carbene (NHC) based on a tetracyclic scaffold by using simple, general, and scalable chemistry is disclosed. The developed route is suitable for introducing multiple substitutions on the tetracyclic scaffold. The utility of the present NHC as a ligand in the Suzuki-Miyaura cross-coupling reaction is demonstrated with a low catalyst loading.</p>10aC-C coupling10acarbenes10aHomogeneous catalysis10aN ligands10asynthetic methods1 aSutar, Revannath, L.1 aKumar, Vinod1 aShingare, Rahul, D.1 aThorat, Shridhar1 aGonnade, Rajesh, G.1 aReddy, Srinivasa  uhttps://library.ncl.res.in/content/general-approach-n-heterocyclic-carbenes-fused-tetracyclic-core-ligands-suzuki-miyaura-001686nas a2200265   4500008004100000022001400041245007600055210006900131260007700200300001400277490000700291520076600298653001301064653002201077653002101099653003301120653002601153100002501179700002201204700002201226700002101248700002401269700002101293856010601314       2015                        eng d  a0947-653900aCatalyst-dependent selectivity in the relay catalytic branching cascade0 aCatalystdependent selectivity in the relay catalytic branching c  aBOSCHSTRASSE 12, D-69469 WEINHEIM, GERMANYbWILEY-V C H VERLAG GMBHcFEB  a2319-23230 v213 a<p>The synthesis of small organic molecules as probes for discovering new therapeutic agents has been an important aspect of chemical biology. One of the best ways to access collections of small molecules is to use various techniques in diversity-oriented synthesis (DOS). Recently, a new form of DOS, namely relay catalytic branching cascades (RCBCs), has been introduced, wherein a common type of starting material reacts with several scaffold-building agents (SBAs) to obtain structurally diverse molecular scaffolds under the influence of catalysts. Herein, the RCBC reaction of a common type of substrate with SBAs is reported to give two different types of molecular scaffolds and their formation is essentially dependent on the type of catalyst used.</p>10aalkynols10acascade synthesis10achemoselectivity10adiversity-oriented synthesis10aHomogeneous catalysis1 aBansode, Avinash, H.1 aShaikh, Aslam, C.1 aKavthe, Rahul, D.1 aThorat, Shridhar1 aGonnade, Rajesh, G.1 aPatil, Nitin, T.  uhttps://library.ncl.res.in/content/catalyst-dependent-selectivity-relay-catalytic-branching-cascade-0