01686nas a2200265   4500008004100000022001400041245007600055210006900131260007700200300001400277490000700291520076600298653001301064653002201077653002101099653003301120653002601153100002501179700002201204700002201226700002101248700002401269700002101293856010601314       2015                        eng d  a0947-653900aCatalyst-dependent selectivity in the relay catalytic branching cascade0 aCatalystdependent selectivity in the relay catalytic branching c  aBOSCHSTRASSE 12, D-69469 WEINHEIM, GERMANYbWILEY-V C H VERLAG GMBHcFEB  a2319-23230 v213 a<p>The synthesis of small organic molecules as probes for discovering new therapeutic agents has been an important aspect of chemical biology. One of the best ways to access collections of small molecules is to use various techniques in diversity-oriented synthesis (DOS). Recently, a new form of DOS, namely relay catalytic branching cascades (RCBCs), has been introduced, wherein a common type of starting material reacts with several scaffold-building agents (SBAs) to obtain structurally diverse molecular scaffolds under the influence of catalysts. Herein, the RCBC reaction of a common type of substrate with SBAs is reported to give two different types of molecular scaffolds and their formation is essentially dependent on the type of catalyst used.</p>10aalkynols10acascade synthesis10achemoselectivity10adiversity-oriented synthesis10aHomogeneous catalysis1 aBansode, Avinash, H.1 aShaikh, Aslam, C.1 aKavthe, Rahul, D.1 aThorat, Shridhar1 aGonnade, Rajesh, G.1 aPatil, Nitin, T.  uhttps://library.ncl.res.in/content/catalyst-dependent-selectivity-relay-catalytic-branching-cascade-001168nas a2200217   4500008004100000022001400041245007500055210006900130260011700199300001200316520037200328653002200700653001100722653001200733653002200745653001100767100002200778700002500800700002100825856010400846       2016                        eng d  a1551-700400aScandium triflate catalyzed unexpected cleavage of C-C bonds in ynones0 aScandium triflate catalyzed unexpected cleavage of CC bonds in y  aC/O ALAN R KATRITZKY, UNIV FLORIDA, DEPT CHEMISTRY, PO BOX 117200, GAINESVILLE, FL 32611 USAbARKAT USA INCcNOV  a223-2323 a<p>An unexpected C-C bond cleavage in ynones in the presence of catalytic amounts of Sc(OTf)(3) in methanol under microwave irradiation has been discussed. The effect of substituent on the regioselectivity of C-C bond cleavage has carefully been addressed by employing various ynones derivatives. The mechanism has been proposed for the observed regioselectivity.</p>10aC-C bond cleavage10aEsters10aKetones10ascandium triflate10aynones1 aKavthe, Rahul, D.1 aBansode, Avinash, H.1 aPatil, Nitin, T.  uhttps://library.ncl.res.in/content/scandium-triflate-catalyzed-unexpected-cleavage-c-c-bonds-ynones