02565nas a2200265   4500008004100000022001400041245010600055210006900161260000800230300001400238490000700252520168100259653002001940653001901960653003401979653001702013653001802030653001702048100002002065700002002085700001402105700001902119700002902138856013202167       2020                        eng d  a1947-293500aNonenzymatic glucose detection in human serum using Ni nanoparticles decorated reduced graphene oxide0 aNonenzymatic glucose detection in human serum using Ni nanoparti  cAUG  a1125-11360 v123 a<p>Reduced Graphene oxide (RGO) decorated with Ni nanoparticles (NiNPs) composites, have been successfully synthesized using a simple hydrothermal method and possessing excellent electrocatalytic activity towards glucose oxidation. The morphological and structural features of RGO-Ni nanocomposites were characterized by field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and energy dispersive spectroscopy (EDS). From TEM, we observed that NiNPs were anchored on RGO sheets. Cyclic Voltammetric (CV) study revealed that the electrocatalytic activity of RGO-Ni nanocomposite with 20% Ni loading (RGONi-20) towards glucose oxidation is better than that shown by bare Glassy Carbon Electrode (GCE), RGO, bare NiNPs, RGONi10 and RGONi-30. The prepared nanocomposites exhibited fast electrocatalytic response (&lt;5 s) towards glucose oxidation. Amperometric study indicates that the present glucose sensor have exhibited excellent performance by offering a lowest detection limit as 5.1 mu M, with linier range from 2 to 5000 mu M and high sensitivity of 896.67 mu A mM(-1) cm(-2). Interference from different anticipatable electroactive substances such as ascorbic acid (AA), uric acid (UA) and dopamine (DA) is not observed. Furthermore, the application of the as prepared sensor was successfully demonstrated for the detection of glucose in human serum and results were comparable to presently used nonenzymatic technique. RGONi-20 nanocomposite electrode holds great promise for the development of biosensors and other electrochemical devices.</p>
10aElectrochemical10aGlucose Sensor10aGraphene-Nickel Nanoparticles10ahydrothermal10aNanocomposite10aNonenzymatic1 aWaichal, Rupali1 aBhirud, Ashwini1 aFouad, H.1 aGosavi, Suresh1 aAshokkumar, Muthupandian  uhttps://library.ncl.res.in/content/nonenzymatic-glucose-detection-human-serum-using-ni-nanoparticles-decorated-reduced-graphene