02670nas a2200241   4500008004100000022001400041245014200055210006900197260009900266300001400365490000700379520169300386653002402079653003102103653002502134653001802159100002102177700002502198700002802223700002302251700002302274856013102297       2008                        eng d  a0032-386100aSynthesis and self-assembling properties of alpha,omega-hydroxy-poly(ethylene oxide) end-capped with 1-isocyanato-3-pentadecylcyclohexane0 aSynthesis and selfassembling properties of alphaomegahydroxypoly  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLANDbELSEVIER SCI LTDcOCT  a4635-46460 v493 a<p>A novel hydrophobic compound, 1-isocyanato-3-pentadecylcyclohexane (PDC) issued from a renewable resource material (Cashew Nut Shell Liquid), is used to end-cap poly(ethylene oxide) (PEO) of different molecular weights. The synthesis, characterization and self-assembling properties of these new associating polymers are reported. In aqueous solution, PDC modified PEOs self-associate into micellar structures which are characterized by neutron scattering. Using a star-polymer model with sticky hard sphere interactions, it is shown that the characteristics of the micelles mainly depend on the size of the PEO chain. In the case of PDC stickers, the aggregation number decreases from 25 to 17 with increasing molecular weight of PEO, from 10 to 20 kg/mol, respectively. The temperature directly impacts the interaction potential between the hydrophilic coronas of PEO which become less repulsive with increasing temperature. Rheological measurements, performed in dilute solution, clearly demonstrate that PEO micelles self-associate into open supramolecular structures. The correlation length of these loose clusters increases with polymer concentration and the hierarchical self-assembly follows the rules of the percolation theory. The sol/gel transition takes place at the overlap concentration of clusters. In semi-dilute solution, the viscoelastic properties of PDC end-capped PEOs are well described by the Maxwell model with a single relaxation mode. The characteristic time of the network follows an Arrhenius temperature dependence with an activation energy of 70 kJ/mol, in very good agreement with the size of PDC stickers. (C) 2008 Elsevier Ltd. All rights reserved.</p>10aAssociating polymer10aHydrophobically end-capped10apoly(ethylene oxide)10aStar micelles1 aKadam, Vijay, S.1 aBadiger, Manohar, V.1 aWadgaonkar, Prakash, P.1 aDucouret, Guylaine1 aHourdet, Dominique  uhttps://library.ncl.res.in/content/synthesis-and-self-assembling-properties-alphaomega-hydroxy-polyethylene-oxide-end-capped-002338nas a2200229   4500008004100000022001400041245016100055210006900216260009900285300001400384490000700398520140000405653002401805653001901829653002001848100002301868700002301891700001901914700002501933700002801958856012201986       2013                        eng d  a0032-386100aThermodynamic behavior of hydrophobically modified polyacrylamide containing random distribution of hydrophobes: experimental and theoretical investigations0 aThermodynamic behavior of hydrophobically modified polyacrylamid  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLANDbELSEVIER SCI LTDcMAY  a2676-26890 v543 a<p>Two series of Hydrophobically Modified Polyacrylamides (HMPAMs) were prepared by free radical copolymerization of trimethylsilylacrylamide with 3-pentadecylcyclohexylacrylamide (PDCAM) or dodecylacrylamide (DDAM) followed by removal of trimethylsilyl protecting groups. The solution properties of HMPAMs were studied in dilute aqueous solution by fluorescence spectroscopy, NMR and viscometry. The properties in aqueous solution of HMPAMs clearly displayed the formation of hydrophobic interactions between alkyl stickers. While dodecyl containing HMPAMs mainly showed a progressive collapse of the copolymer coil with the increasing fraction of hydrophobic moieties (weak intra-chain associations), pentadecylcyclohexyl groups containing HMPAMs exhibited a much lower solubility in water due to strong intra- and inter-chain associations. Experimental data were analyzed using the mean field theory developed by Semenov and Rubinstein (SR) for associating polymers. Using a set of realistic parameters, taking into account the solubility of the backbone, the fraction of stickers and the strength of hydrophobic attractions, we show that the SR model offers a quantitative description of the thermodynamic properties of HMPAMs in terms of individual and collective behavior of polymers chains; i.e. swelling and phase separation, respectively. (C) 2013 Elsevier Ltd. All rights reserved.</p>10aAssociating polymer10aPolyacrylamide10aSelf-assembling1 aHourdet, Dominique1 aDucouret, Guylaine1 aVarghese, Sony1 aBadiger, Manohar, V.1 aWadgaonkar, Prakash, P.  uhttps://library.ncl.res.in/content/thermodynamic-behavior-hydrophobically-modified-polyacrylamide-containing-random-002489nas a2200301   4500008004100000022001400041245013200055210006900187260009900256300001200355490000800367520135800375653002301733653002701756653001401783653001301797653002201810653003201832100002201864700002401886700002801910700002401938700002301962700002301985700002302008700002502031856013102056       2015                        eng d  a0144-861700aSynthesis and characterization of PEPO grafted carboxymethyl guar and carboxymethyl tamarind as new thermo-associating polymers0 aSynthesis and characterization of PEPO grafted carboxymethyl gua  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLANDbELSEVIER SCI LTDcMAR  a331-3380 v1173 a<p>New thermo associating polymers were designed and synthesized by grafting amino terminated poly(ethylene oxide-co-propylene oxide) (PEPO) onto carboxymethyl guar (CMG) and carboxymethyl tamarind (CMT). The grafting was performed by coupling reaction between-NH2 groups of PEPO and -COOH groups of CMG and CMT using water-soluble EDC/NHS as coupling agents. The grafting efficiency and the temperature of thermo-association, T-assoc in the copolymer were studied by NMR spectroscopy. The graft copolymers, CMG-g-PEPO and CMT-g-PEPO exhibited interesting thermo-associating behavior which was evidenced by the detailed rheological and fluorescence measurements. The visco-elastic properties (storage modulus, G'; loss modulus, G'') of the copolymer solutions were investigated using oscillatory shear experiments. The influence of salt and surfactant on the T-assoc was also studied by rheology, where the phenomenon of ``Salting out'' and ``Salting in'' was observed for salt and surfactant, respectively, which can give an easy access to tunable properties of these copolymers. These thermo-associating polymers with biodegradable nature of CMG and CMT can have potential applications as smart injectables in controlled release technology and as thickeners in cosmetics and pharmaceutical formulations. (C) 2014 Elsevier Ltd. All rights reserved.</p>10aCarboxymethyl guar10aCarboxymethyl tamarind10aPluronics10aRheology10aSolution behavior10aThermo-associating polymers1 aGupta, Nivika, R.1 aTorris, Arun, A. T.1 aWadgaonkar, Prakash, P.1 aRajamohanan, P., R.1 aDucouret, Guylaine1 aHourdet, Dominique1 aCreton, Costantino1 aBadiger, Manohar, V.  uhttps://library.ncl.res.in/content/synthesis-and-characterization-pepo-grafted-carboxymethyl-guar-and-carboxymethyl-tamarind-102113nas a2200289   4500008004100000022001400041245009600055210006900151260000900220300001400229490000700243520115400250653001501404653001301419653002401432653002601456653003001482653002301512100001801535700002501553700003501578700002801613700002301641700001801664700002301682856011801705       2026                        eng d  a2642-415000aViscoelastic behaviors of hyaluronic derivatives as a function of pH, salt, and temperature0 aViscoelastic behaviors of hyaluronic derivatives as a function o  cMAR   a1505-15170 v643 a<p>
	Hyaluronic acid and its derivatives are essential polysaccharides widely used in the bio-medical field for their applications in tissue engineering and controlled drug delivery. By revisiting the wide variety of rheological behavior of aqueous hyaluronan solutions as a function of pH, we develop in this work a comparative study between solutions of native hyaluronan (HA) and its derivative (HA-PEPO) obtained by grafting onto thermoresponsive side-chains of poly(ethylene oxide-co-propylene oxide) characterized by a phase transition around body temperature. Based on a large dataset obtained at a fixed polymer concentration, by changing either the chemical composition of the chain and/or the environmental conditions (pH, temperature, added salt), we show that the viscoelastic properties of hyaluronan solutions can be controlled over more than three decades of amplitude with the possibility to get either liquid or gel states, regardless of temperature, as well as sol/gel transitions induced by cooling or heating by the interplay between hydrogen bonds, hydrophobic interactions, and cation binding induced by potassium salts.</p>
10ahyaluronan10aHydrogel10apH-induced gelation10asalt-induced gelation10athermoresponsive polymers10atissue engineering1 aKadam, Yogesh1 aBadiger, Manohar, V.1 aRajamohanan, Pattuparambil, R.1 aWadgaonkar, Prakash, P.1 aDucouret, Guylaine1 aMerland, Theo1 aHourdet, Dominique  uhttps://library.ncl.res.in/content/viscoelastic-behaviors-hyaluronic-derivatives-function-ph-salt-and-temperature