01919nas a2200241   4500008004100000022001400041245007400055210006900129260000800198490000700206520118700213653002001400653001901420653001601439653003101455653001201486100001501498700001601513700001801529700001501547700001401562856010101576       2021                        eng d  a0962-107500aGlycosyltransferases: the multifaceted enzymatic regulator in insects0 aGlycosyltransferases the multifaceted enzymatic regulator in ins  cAPR0 v303 a<p>Glycosyltransferases (GTs) catalyse the reaction of glyco-conjugation of various biomolecules by transferring the saccharide moieties from an activated nucleotide sugar to nucleophilic glycosyl acceptor. In insects, GTs show diverse temporal and site-specific expression patterns and thus play significant roles in forming the complex biomolecular structures that are necessary for insect survival, growth and development. Several insects exhibit GT-mediated detoxification as a key defence strategy against plant allelochemicals and xenobiotic compounds, as well as a mechanism for pesticide cross-resistance. Also, these enzymes act as crucial effectors and modulators in various developmental processes of insects such as eye development, UV shielding, cuticle formation, epithelial development and other specialized functions. Furthermore, many of the known insect GTs have been shown to play a fundamental role in other physiological processes like body pigmentation, cuticular tanning, chemosensation and stress response. This review provides a detailed overview of the multifaceted functionality of insect GTs and summarizes numerous case studies associated with it.</p>
10aAllelochemicals10aDetoxification10aDevelopment10aglycosyltransferases (GTs)10ainsects1 aNagare, M.1 aAyachit, M.1 aAgnihotri, A.1 aSchwab, W.1 aJoshi, R.  uhttps://library.ncl.res.in/content/glycosyltransferases-multifaceted-enzymatic-regulator-insects