01202nas a2200217 4500008004100000022001400041245012100055210006900176260000900245300001400254490000700268520042400275100002400699700002200723700002400745700001900769700001900788700001900807700002800826856013000854 2021 eng d a0022-326300aTriazine-based janus G-C nucleobase as a building block for self-assembly, peptide nucleic acids, and smart polymers0 aTriazinebased janus GC nucleobase as a building block for selfas cFEB  a3186-31950 v863 a

This communication reports on the utility of a triazine-based self-assembling system, reminiscent of a Janus G-C nucleobase, as a building block for developing (1) supramolecular polymers, (2) peptide nucleic acids (PNAs), and (3) smart polymers. The strategically positioned self-complementary triple H-bonding arrays DDA and AAD facilitate efficient self-assembly, leading to a linear supramolecular polymer.

1 aMeena, Chhuttan, L.1 aSingh, Dharmendra1 aKizhakeetil, Bhavya1 aPrasad, Manasa1 aGeorge, Malini1 aTothadi, Srinu1 aSanjayan, Gangadhar, J. uhttps://library.ncl.res.in/content/triazine-based-janus-g-c-nucleobase-building-block-self-assembly-peptide-nucleic-acids-and02608nas a2200253 4500008004100000022001400041245011100055210006900166260000800235300001600243490000600259520173400265653001601999653002102015653001802036653001702054653002802071100002402099700002302123700002202146700002902168700002702197856013002224 2025 eng d a2637-610500aTriple G-C-T base-coded nucleobase self-assembling monomers featuring polymerizable groups for 3D printing0 aTriple GCT basecoded nucleobase selfassembling monomers featurin cNOV a15619-156280 v73 a

Self-assembling monomers (SAMs) offer a versatile strategy for enhancing the performance of photoresins in Digital Light Processing (DLP) 3D printing. In this work, we report the design and synthesis of two photoprintable, nucleobase-inspired SAMs featuring a triple G-C-T base-coded hydrogen-bonding motif. This SAM was formulated using 2-hydroxyethyl acrylate (2-HEA), 1,6-hexanediol diacrylate (HDDA), and diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide (TPO) to prepare UV-curable resins suitable for high-resolution DLP printing. Remarkably, the printed samples exhibited supramolecular self-assembly, facilitated by dynamic hydrogen bonding, demonstrating a notable enhancement in thermal and mechanical performance when compared to the control sample. Thermal properties evaluated by a differential scanning calorimeter revealed an increase in the glass transition temperature (T-g) from 15 degrees C to 54 degrees C for SAM-incorporated printed materials. Mechanical testing demonstrated a >200% increase in toughness and >150% improvement in tensile strength relative to the unmodified resin while maintaining or exceeding the original elongation at break (up to similar to 74%). Variable-temperature FTIR spectroscopy confirmed the presence of thermally responsive supramolecular interactions. Notably, self-healing behavior was observed in both GCT-A 15 wt % and GCT-S 15 wt % formulations, indicating partial recovery of mechanical integrity under mild thermal conditions due to reversible hydrogen bonding. These findings demonstrate the potential of SAMs as functional additives for developing robust, thermally stable, and self-healing DLP-printed materials for advanced engineering applications.

10a3D printing10ahydrogen bonding10aSelf-assembly10aSelf-healing10aTriple G-C-T nucleobase1 aGawande, Akshay, J.1 aKamble, Ganesh, N.1 aSingh, Dharmendra1 aSanjayan, Gangadhar., J.1 aNair, Kiran, Sukumaran uhttps://library.ncl.res.in/content/triple-g-c-t-base-coded-nucleobase-self-assembling-monomers-featuring-polymerizable-groups01381nas a2200205 4500008004100000022001400041245015300055210006900208260000800277300001400285490000700299520061300306100002200919700001900941700001700960700001800977700002700995700002801022856012501050 2025 eng d a0022-326300aTriple G-C-T base-coded self-assembling water-soluble nucleobase monomers with a broad scope for biomaterial and protein bioconjugation applications0 aTriple GCT basecoded selfassembling watersoluble nucleobase mono cFEB a2822-28290 v903 a

We report self-assembling water-soluble nucleobase monomers with a broad scope for biomaterial and protein bioconjugation applications. These nucleobase monomers are adorned with nature-inspired triple G-C-T nucleobases featuring three recognition sites: DDA (G mimic), DAA (C mimic), and ADA (T mimic). Using readily accessible starting materials, these monomers can be synthesized in excellent yields, making them good choices for diverse applications. Their unique structural features, coupled with their water solubility, may offer exciting opportunities for the creation of new biomaterials.

1 aSingh, Dharmendra1 aGone, Nilu, V.1 aBandi, Kiran1 aDavis, Disiya1 aNair, Kiran, Sukumaran1 aSanjayan, Gangadhar, J. uhttps://library.ncl.res.in/content/triple-g-c-t-base-coded-self-assembling-water-soluble-nucleobase-monomers-broad-scope