01124nas a2200193   4500008004100000022001400041245018200055210006900237260007100306300001400377490000700391520029000398100002400688700002500712700002300737700002300760700002300783856012400806       2005                        eng d  a0022-326300aDiastereoselective amidoalkylation of (3S,7aR)-6-benzyl-7-hydroxy-3-phenyltetra-hydro-5H-imidazo[1,5-c][1, 3]thiazol-5-one : a short and highly efficient synthesis of (+)-biotin0 aDiastereoselective amidoalkylation of 3S7aR6benzyl7hydroxy3pheny  a1155 16TH ST, NW, WASHINGTON, DC 20036 USAbAMER CHEMICAL SOCcMAR  a1901-19030 v703 a<p>A short and highly efficient synthesis of W-biotin in 10 steps with 20% overall yield has been achieved from L-cysteine involving amidoalkylation of hydroxy imidazothiazolone 4 via an acyliminium ion intermediate to furnish C-7-substituted imidazothiazolones 5b as the key step.</p>1 aChavan, Subhash, P.1 aChittiboyina, A., G.1 aRavindranathan, T.1 aKamat, Subhash, K.1 aKalkote, Uttam, R.  uhttps://library.ncl.res.in/content/diastereoselective-amidoalkylation-3s7ar-6-benzyl-7-hydroxy-3-phenyltetra-hydro-5h-101062nas a2200181   4500008004100000022001400041245009000055210006900145260010600214300001200320490000700332520035600339100002400695700001600719700001500735700002300750856010700773       2005                        eng d  a0040-403900aEfficient stereoselective synthesis of (2S,4S,5R)-(-)- and (2R,4R,5S)-(+)-bulgecinine0 aEfficient stereoselective synthesis of 2S4S5R and 2R4R5Sbulgecin  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcJAN  a439-4410 v463 a<p>A short synthetic route to (-)-and (+)-bulgecinine, the amino acid moiety of the bulgecins was achieved from the readily available nonchiral pool starting material cis-2-butene-1,4-diol in which a Claisen orthoester rearrangement and a Sharpless asymmetric dihydroxylation were used as the key steps. (C) 2004 Elsevier Ltd. All rights reserved.</p>1 aChavan, Subhash, P.1 aPraveen, C.1 aSharma, P.1 aKalkote, Uttam, R.  uhttps://library.ncl.res.in/content/efficient-stereoselective-synthesis-2s4s5r-and-2r4r5s-bulgecinine-000937nas a2200229   4500008004100000022001400041245007300055210006900128260007600197300001100273520014500284653000600429653002100435653002500456653001600481100002300497700002300520700002000543700002200563700002400585856009800609       2005                        eng d  a0308-234200aNew method for the preparation of 1,2-benzisoxazole-3-carboxaldehyde0 aNew method for the preparation of 12benzisoxazole3carboxaldehyde  aPO BOX 314, ST ALBANS AL1 4ZG, HERTS, ENGLANDbSCIENCE REVIEWS LTDcFEB  a99-1003 a<p>Synthesis of 1,2-benzisoxazole-3-carboxaldehyde is achieved from 3-methyl 1,2-benzisoxazole via 3-ethoxymethyl-1,2-benzisoxazole (4).</p>10a110a2-benzisoxazoles10abenzylic bromination10aindoxazenes1 aKalkote, Uttam, R.1 aPanchgalle, S., R.1 aMahakal, K., K.1 aChoudhary, S., M.1 aChavan, Sayalee, R.  uhttps://library.ncl.res.in/content/new-method-preparation-12-benzisoxazole-3-carboxaldehyde-001787nas a2200313   4500008004100000022001400041245009100055210006900146260006900215300001000284490000700294520075800301653000601059653003201065653003601097653001401133653002401147653002301171653001201194653001801206653001201224653002301236100002501259700001301284700002301297700001201320700002601332856011501358       2005                        eng d  a1369-703X00aNovel enzymatic route for kinetic resolution of (+/-)1,4-benzodioxan-2-carboxylic acid0 aNovel enzymatic route for kinetic resolution of 14benzodioxan2ca  aPO BOX 564, 1001 LAUSANNE, SWITZERLANDbELSEVIER SCIENCE SAcDEC  a66-710 v273 aEthyl 1,4-benzodioxan-2-carboxylate is used as an intermediate compound for the production of drug doxazosin mesylate. The title compound was kinetically resolved to get S-enantiomer of ethyl 1,4-benzodioxan 2-carboxylate in a simple lipase catalyzed transesterificafion reaction. Ethyl acetate was used as reaction medium as well as acyl donor. The influence of the enzyme source and time of reaction on the enantio selectivity of product were studied. Lipase from Candida antartica-B (Novozyme A/S) catalyzed transesterification reaction with good enantio selectivity towards S-enantiomer. The high enantiomeric ratio, E= 160, provided S-2 an acceptable chemical yield (50%) and enaritiomeric excess (>95%). (c) 2005 Elsevier B.V. All rights reserved.10a110a4-benzodioxan-2-carboxylate10a4-benzodioxan-2-carboxylic acid10adoxazosin10aenantio selectivity10aenantiomeric ratio10aethyl 110aethyl acetate10aLipases10atransesterfication1 aKasture, Sangita, M.1 aVarma, R1 aKalkote, Uttam, R.1 aNene, S1 aKulkarni, Bhaskar, D.  uhttps://library.ncl.res.in/content/novel-enzymatic-route-kinetic-resolution-14-benzodioxan-2-carboxylic-acid-001066nas a2200253   4500008004100000022001400041245008700055210006900142260008600211300001200297490000700309520017200316653001200488653002200500653003200522653001600554653001400570100002400584700002500608700002300633700002300656700001700679856011600696       2005                        eng d  a0039-791100aSimple, concise, stereocontrolled synthesis of (8E,10Z)-pentadecadien-1-ol acetate0 aSimple concise stereocontrolled synthesis of 8E10Zpentadecadien1  a325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USAbTAYLOR & FRANCIS INCcAUG  a987-9940 v353 a<p>A simple, concise, and stereocontrolled synthesis of (8E, 10Z)-pentadecadien-l -ol acetate involving a Cadiot-Chodkiewicz reaction as the key step is described.</p>10aacetate10aAcrobasis vaccini10aCadiot-Chodkiewicz reaction10adiacetylene10aPheromone1 aChavan, Subhash, P.1 aKharul, Rajendra, K.1 aKamat, Subhash, K.1 aKalkote, Uttam, R.1 aKale, R., R.  uhttps://library.ncl.res.in/content/simple-concise-stereocontrolled-synthesis-8e10z-pentadecadien-1-ol-acetate-001356nas a2200229   4500008004100000022001400041245014900055210006900204260007300273300001000346490000700356520047800363653002600841653002500867653001300892653001500905100002300920700001900943700002600962700001900988856011901007       2006                        eng d  a1381-117700aConvenient chemoenzymatic synthesis of (1S,7aS)-1-hydroxy-5-oxo-4-(2 `-carboxyethyl)-7a-methyltetrahydro-indane - a key intermediate of steroids0 aConvenient chemoenzymatic synthesis of 1S7aS1hydroxy5oxo42 carbo  aPO BOX 211, 1000 AE AMSTERDAM, NETHERLANDSbELSEVIER SCIENCE BVcMAY  a38-430 v403 a<p>A porcine pancreatic lipase mediated enzymatic hydrolysis of (+/-)-1-acetoxy-5-oxo-4-(2 `-carbomethoxyethyl)-7a-methyltetrahydroindane (5b) furnished (1S,7aS)-1-acetoxy-5-oxo-4-(2 `-carbomethoxyethyl)-7a-methyltetrahydro-indane (9) and (1R,7aR)-1-hydroxy-5-oxo-4-(2 `-carbomethoxyethyl)-7a-methyltetrahydro-indane (8) with &gt; 99% e.e. which on further chemical hydrolysis gave 1 and ent-1, key intermediates of steroids. (c) 2006 Elsevier B.V. All rights reserved.</p>10achemoenzymatic method10aEnzymatic hydrolysis10asteroids10aterpenoids1 aKalkote, Uttam, R.1 aPurude, A., N.1 aPuranik, Vedavati, G.1 aGurjar, M., K.  uhttps://library.ncl.res.in/content/convenient-chemoenzymatic-synthesis-1s7as-1-hydroxy-5-oxo-4-2-carboxyethyl-7a-000864nas a2200181   4500008004100000022001400041245007600055210006800131260007100199300001400270490000700284520019800291100002400489700002000513700002400533700002300557856010200580       2006                        eng d  a0022-326300aFirst enantiospecific synthesis of (-)-parvifoline and (-)-curcuquinone0 aFirst enantiospecific synthesis of parvifoline and curcuquinone  a1155 16TH ST, NW, WASHINGTON, DC 20036 USAbAMER CHEMICAL SOCcNOV  a8986-89880 v713 a<p>The first enantiospecific synthesis of (-)-parvifoline, employing ring-closing metathesis as the key step, and (-)-curcuquinone from naturally occurring (R)-(+)-citronellal is described.</p>1 aChavan, Subhash, P.1 aThakkar, Mahesh1 aJogdand, Ganesh, F.1 aKalkote, Uttam, R.  uhttps://library.ncl.res.in/content/first-enantiospecific-synthesis-parvifoline-and-curcuquinone-001020nas a2200241   4500008004100000022001400041245007500055210006900130260010600199300001400305490000700319520016800326653002900494653002000523653001900543653000800562653002000570100002400590700002000614700001600634700002300650856010500673       2006                        eng d  a0040-403900aRing closing metathesis approach to the indole alkaloid mitralactonine0 aRing closing metathesis approach to the indole alkaloid mitralac  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcDEC  a9301-93030 v473 a<p>An efficient utilisation of RCM leading to a convenient synthesis of a pentacyclic indole alkaloid is described. (c) 2006 Elsevier Ltd. All rights reserved.</p>10acorynanthe type alkaloid10aDihydroxylation10amitralactonine10aRCM10aSwern oxidation1 aChavan, Subhash, P.1 aSharma, Pallavi1 aSivappa, R.1 aKalkote, Uttam, R.  uhttps://library.ncl.res.in/content/ring-closing-metathesis-approach-indole-alkaloid-mitralactonine-000888nas a2200241   4500008004100000022001400041245005200055210004600107260008600153300001400239490000700253520012400260653002000384653001400404653001700418653001800435653001600453100002400469700002800493700002200521700002300543856008000566       2007                        eng d  a0039-791100aConvenient formal synthesis of (+/-)-paroxetine0 aConvenient formal synthesis of paroxetine  a325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USAbTAYLOR & FRANCIS INCcSEP  a3143-31490 v373 a<p>A formal total synthesis of antidepressant (+/-)-paroxetine employing a solvent-free Heck reaction is disclosed.</p>10aantidepressants10acarbamate10aelectrophile10aHeck reaction10apiperidines1 aChavan, Subhash, P.1 aKhobragade, Dushant, A.1 aPathak, Ashok, B.1 aKalkote, Uttam, R.  uhttps://library.ncl.res.in/content/convenient-formal-synthesis-paroxetine-000856nas a2200205   4500008004100000022001400041245007000055210006300125260007500188300001400263520013000277653001500407653001500422653002800437653001400465100002400479700002600503700002300529856009800552       2007                        eng d  a0039-788100aEfficient and practical total synthesis of (+/-)-alpha-cuparenone0 aEfficient and practical total synthesis of alphacuparenone  aRUDIGERSTR 14, D-70469 STUTTGART, GERMANYbGEORG THIEME VERLAG KGcDEC  a3827-38303 a<p>A one-pot cyclopentannulation approach as the key step for the total synthesis of (+/-)-alpha-cuparenone is described.</p>10aAlkylation10aannulation10ahydroboration-oxidation10areduction1 aChavan, Subhash, P.1 aDhawane, Abasaheb, N.1 aKalkote, Uttam, R.  uhttps://library.ncl.res.in/content/efficient-and-practical-total-synthesis-alpha-cuparenone-000890nas a2200169   4500008004100000022001400041245009700055210006900152260010600221300001200327490000700339520018100346100002400527700002600551700002300577856012000600       2007                        eng d  a0040-403900aFacile total synthesis of (+/-)-alpha-cuparenone employing diallylation and RCM as key steps0 aFacile total synthesis of alphacuparenone employing diallylation  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcFEB  a965-9660 v483 a<p>A short and concise total synthesis of alpha-cuparenone employing one-pot diallylation and RCM as the key steps is described. (c) 2006 Elsevier Ltd. All rights reserved.</p>1 aChavan, Subhash, P.1 aDhawane, Abasaheb, N.1 aKalkote, Uttam, R.  uhttps://library.ncl.res.in/content/facile-total-synthesis-alpha-cuparenone-employing-diallylation-and-rcm-key-steps00905nas a2200169   4500008004100000022001400041245008900055210006900144260010600213300001200319490000700331520021400338100002400552700002000576700002300596856011600619       2007                        eng d  a0040-403900aFirst enantiospecific synthesis of (-)-heritol: absolute configuration determination0 aFirst enantiospecific synthesis of heritol absolute configuratio  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcJAN  a643-6460 v483 a<p>The first enantiospecific synthesis of (-)-heritol, from naturally occurring (R)-(+)-citronellal and confirmation of its absolute configuration, is described. (c) 2006 Elsevier Ltd. All rights reserved.</p>1 aChavan, Subhash, P.1 aThakkar, Mahesh1 aKalkote, Uttam, R.  uhttps://library.ncl.res.in/content/first-enantiospecific-synthesis-heritol-absolute-configuration-determination01048nas a2200229   4500008004100000022001400041245007900055210006900134260007500203300001000278520024800288653001400536653001500550653001700565653002100582653001600603100002400619700002000643700002300663700002300686856010900709       2007                        eng d  a0936-521400aPractical and facile approach towards indole alkaloids: (-)-mitralactonine0 aPractical and facile approach towards indole alkaloids mitralact  aRUDIGERSTR 14, D-70469 STUTTGART, GERMANYbGEORG THIEME VERLAG KGcJAN  a79-823 a<p>An efficient approach to (-)-mitralactonine using Pictet-Spengler cyclisation with a highly functionalised masked aldehyde is described. Sharpless asymmetric dihydroxylation (SAD) is utilised to introduce chirality in the key substrate.</p>10aalkaloids10aasymmetric10acyclisations10adihydroxylations10athioacetats1 aChavan, Subhash, P.1 aSharma, Pallavi1 aSivappa, Rasapalli1 aKalkote, Uttam, R.  uhttps://library.ncl.res.in/content/practical-and-facile-approach-towards-indole-alkaloids-mitralactonine00989nas a2200217   4500008004100000022001400041245004700055210004700102260010600149300001400255490000700269520028000276653001300556653001500569653001700584653002000601100002400621700002200645700002300667856008100690       2007                        eng d  a0040-403900aPractical formal synthesis of camptothecin0 aPractical formal synthesis of camptothecin  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcSEP  a6561-65630 v483 a<p>The synthesis of the DE ring of camptothecin using simple and inexpensive starting materials, employing an addition elimination reaction and selective esterification of an aliphatic carboxylic acid as key steps is described. (C) 2007 Elsevier Ltd. All rights reserved.</p>10aalkaloid10aAnticancer10acamptothecin10aNatural product1 aChavan, Subhash, P.1 aPathak, Ashok, B.1 aKalkote, Uttam, R.  uhttps://library.ncl.res.in/content/practical-formal-synthesis-camptothecin-000783nas a2200217   4500008004100000022001400041245004500055210003900100260008600139300001400225490000700239520008900246653001900335653002200354653002100376100002400397700002800421700002000449700002300469856007300492       2007                        eng d  a0039-791100aPractical synthesis of (+/-)-venlafaxine0 aPractical synthesis of venlafaxine  a325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USAbTAYLOR & FRANCIS INCcNOV  a3901-39060 v373 a<p>A practical total synthesis of antidepressant (+/-)-venlafaxine is disclosed.</p>10aantidepressant10aGrignard reaction10aMichael addition1 aChavan, Subhash, P.1 aKhobragade, Dushant, A.1 aThakkar, Mahesh1 aKalkote, Uttam, R.  uhttps://library.ncl.res.in/content/practical-synthesis-venlafaxine-000983nas a2200241   4500008004100000022001400041245004900055210004900104260008600153300001400239490000700253520022800260653001600488653001400504653001200518653002100530653002000551100002400571700002200595700001800617700002300635856008300658       2007                        eng d  a0039-791100aShort and efficient synthesis of rubrolide E0 aShort and efficient synthesis of rubrolide E  a325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USAbTAYLOR & FRANCIS INCcDEC  a4253-42630 v373 a<p>Short and efficient synthesis of rubrolide E from commercially available 4-methoxyacetophenone, employing ring-closing metathesis, Knoevenagel condensation, and Reformatsky reactions, are the key steps are described.</p>10aantibiotics10aantitumor10aEpoxide10aNatural products10aTotal synthesis1 aChavan, Subhash, P.1 aPathak, Ashok, B.1 aPandey, Ankur1 aKalkote, Uttam, R.  uhttps://library.ncl.res.in/content/short-and-efficient-synthesis-rubrolide-e-000986nas a2200217   4500008004100000022001400041245010300055210006900158260007500227300001400302520017700316653001400493653001400507653001700521653002100538653001400559100002400573700002200597700002300619856012600642       2007                        eng d  a0936-521400aTotal synthesis of (+)-camptothecin via an intramolecular palladium-catalyzed cyclization strategy0 aTotal synthesis of camptothecin via an intramolecular palladiumc  aRUDIGERSTR 14, D-70469 STUTTGART, GERMANYbGEORG THIEME VERLAG KGcOCT  a2635-26383 a<p>The novel cascade intramolecular Pd-catalyzed cyclization followed by aromatization for the construction Of D ring of (+)-camptothecin as a key step is demonstrated.</p>10aalkaloids10aantitumor10acyclizations10aNatural products10aPalladium1 aChavan, Subhash, P.1 aPathak, Ashok, B.1 aKalkote, Uttam, R.  uhttps://library.ncl.res.in/content/total-synthesis-camptothecin-intramolecular-palladium-catalyzed-cyclization-strategy-000996nas a2200241   4500008004100000022001400041245005900055210005900114260008600173300001400259490000700273520021100280653001300491653002100504653002000525653000800545653002000553100002400573700002200597700002600619700002300645856008600668       2007                        eng d  a0039-791100aTotal synthesis of pulchellalactam via an RCM strategy0 aTotal synthesis of pulchellalactam via an RCM strategy  a325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USAbTAYLOR & FRANCIS INCcMAY  a1503-15100 v373 a<p>Total synthesis of (Z) pulchellalactam, a CD protein tyrosine phosphatase inhibitor, from commercially available methallyl chloride employing ring-closure metathesis (RCM) as a key step is described.</p>10aalkaloid10aNatural products10apulchellalactam10aRCM10aTotal synthesis1 aChavan, Subhash, P.1 aPathak, Ashok, B.1 aDhawane, Abasaheb, N.1 aKalkote, Uttam, R.  uhttps://library.ncl.res.in/content/total-synthesis-pulchellalactam-rcm-strategy-001436nas a2200253   4500008004100000022001400041245013600055210006900191260006100260300001200321490000700333520051200340653000600852653003200858653003600890653001400926653002300940653001200963100001600975700002500991700001701016700002301033856012601056       2008                        eng d  a0959-399300aLipases catalyzed enantioselective hydrolysis of (R,S)-methyl 1,4-benzodioxan-2-carboxylate intermediate for (S)-doxazosin mesylate0 aLipases catalyzed enantioselective hydrolysis of RSmethyl 14benz  a233 SPRING STREET, NEW YORK, NY 10013 USAbSPRINGERcAPR  a577-5790 v243 a<p>(S)-1,4-benzodioxan-2-carboxylic acid-1 is used as starting compound for the production of the more effective (S) enantiomer of the drug doxazosin mesylate. The catalytic ability of some commercial lipases for preparations of (S) enantiomer of 1 from (+/-) methyl 1,4-benzodioxin-2-carboxylate-2 is reported. Lipases from bacterial sources were more successful in resolving the ester than those from the yeast lipases. About 85% enantiomerically pure ester was achieved by lipase from alcaligenes sp.</p>10a110a4-benzodioxan-2-carboxylate10a4-benzodioxan-2-carboxylic acid10adoxazosin10aEnantioselectivity10aLipases1 aVarma, Rita1 aKasture, Sangita, M.1 aNene, Sanjay1 aKalkote, Uttam, R.  uhttps://library.ncl.res.in/content/lipases-catalyzed-enantioselective-hydrolysis-rs-methyl-14-benzodioxan-2-carboxylate-001219nas a2200217   4500008004100000022001400041245012900055210006900184260007500253300001400328520036400342653002300706653001400729653001400743653002100757653002500778100002400803700002600827700002300853856012500876       2008                        eng d  a0936-521400aTandem aza-michael-condensation-aldol cyclization reaction: approach to the construction of DE synthon of (+/-)-camptothecin0 aTandem azamichaelcondensationaldol cyclization reaction approach  aRUDIGERSTR 14, D-70469 STUTTGART, GERMANYbGEORG THIEME VERLAG KGcNOV  a2781-27843 a<p>An efficient synthesis of the DE ring of camptothecin, employing a Reformatsky and a tandem one-pot, three-step transformation involving aza-Michael reaction, condensation with ethyl malonyl chloride followed by intramolecular `aldol' reaction to furnish the dihydropyridone derivative from commercially available starting materials, has been achieved.</p>10aAldol cyclizations10aalkaloids10aantitumor10aNatural products10aReformatsky reaction1 aChavan, Subhash, P.1 aDhawane, Abasaheb, N.1 aKalkote, Uttam, R.  uhttps://library.ncl.res.in/content/tandem-aza-michael-condensation-aldol-cyclization-reaction-approach-construction-de-001028nas a2200181   4500008004100000022001400041245010000055210006900155260010600224300001400330490000700344520026700351100002700618700002500645700002400670700002300694856012900717       2009                        eng d  a0957-416600aOrganocatalytic enantioselective synthesis of beta-blockers: (S)-propranolol and (S)-naftopidil0 aOrganocatalytic enantioselective synthesis of betablockers Sprop  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcAUG  a1767-17700 v203 a<p>An efficient enantioselective synthesis of beta-adrenergic blockers (S)-propranolol and (S)-naftopidil with &gt; 98% ee using an L-proline-catalyzed alpha-aminoxylation of an aldehyde as a key step is described. (c) 2009 Elsevier Ltd. All rights reserved.</p>1 aPanchgalle, Sharad, P.1 aGore, Rohitkumar, G.1 aChavan, Subhash, P.1 aKalkote, Uttam, R.  uhttps://library.ncl.res.in/content/organocatalytic-enantioselective-synthesis-beta-blockers-s-propranolol-and-s-naftopidil-001279nas a2200241   4500008004100000022001400041245009800055210006900153260010600222300001200328490000700340520034100347653002300688653002100711653003200732653002100764653003100785100002300816700002800839700002300867700002600890856012100916       2009                        eng d  a0385-541400aStudies toward the total synthesis of carba analogue of motif C OF M. TB cell wall AG complex0 aStudies toward the total synthesis of carba analogue of motif C   aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcFEB  a909-9250 v773 a<p>Herein we describe the synthesis of the carba analogue of motif C of arabinogalactan complex present in M tuberculosis cell wall. Pd(0) catalyzed allylic alkylation and Fraser-Reid's glycosidation are the two key reactions that were employed for the synthesis of central glycosyl accepter unit and the glycosylation respectively.</p>10aAllylic Alkylation10adesymmetrization10aFraser-Reid's Glycosidation10aM. Tb Ag Complex10aMycobacterium tuberculosis1 aGurjar, Mukund, K.1 aReddy, Challa, Nageswar1 aKalkote, Uttam, R.1 aChorghade, Mukund, S.  uhttps://library.ncl.res.in/content/studies-toward-total-synthesis-carba-analogue-motif-c-m-tb-cell-wall-ag-complex-001100nas a2200181   4500008004100000022001400041245014500055210006900200260010600269300001400375490000700389520030100396100002700697700002400724700002400748700002300772856012300795       2010                        eng d  a0040-403900aEnantioselective synthesis of (R)-(+)-alpha-lipoic acid via proline-catalyzed sequential alpha-aminoxylation and HWE olefination of aldehyde0 aEnantioselective synthesis of Ralphalipoic acid via prolinecatal  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcJUL  a3587-35890 v513 a<p>An efficient enantioselective synthesis of (R)-(+)-alpha-lipoic acid is described, in high optical purity (&gt;97% ee), using L-proline-catalyzed sequential alpha-aminoxylation and Horner-Wadsworth-Emmons olefination of aldehyde as the key step. (C) 2010 Elsevier Ltd. All rights reserved.</p>1 aPanchgalle, Sharad, P.1 aJogdand, Ganesh, F.1 aChavan, Subhash, P.1 aKalkote, Uttam, R.  uhttps://library.ncl.res.in/content/enantioselective-synthesis-r-alpha-lipoic-acid-proline-catalyzed-sequential-alpha-000938nas a2200169   4500008004100000022001400041245008000055210006900135260010600204300001400310490000700324520026300331100002400594700002600618700002300644856010100667       2010                        eng d  a0040-403900aFormal synthesis of (+/-)-camptothecin via tricyclic lactone as key synthon0 aFormal synthesis of camptothecin via tricyclic lactone as key sy  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcJUN  a3099-31010 v513 a<p>Formal synthesis of (+/-)-camptothecin via CDE tricyclic lactone employing tandem Michael addition, Dieckmann condensation and addition-elimination reaction as key steps starting from glycinate is described. (C) 2010 Elsevier Ltd. All rights reserved.</p>1 aChavan, Subhash, P.1 aDhawane, Abasaheb, N.1 aKalkote, Uttam, R.  uhttps://library.ncl.res.in/content/formal-synthesis-camptothecin-tricyclic-lactone-key-synthon-001127nas a2200181   4500008004100000022001400041245014500055210006900200260010600269300001400375490000700389520032200396100002700718700002400745700002400769700002300793856012900816       2010                        eng d  a0957-416600aOrganocatalytic asymmetric synthesis of (-)-delta-coniceine based on sequential proline-catalyzed asymmetric alpha-amination-HWE olefination0 aOrganocatalytic asymmetric synthesis of deltaconiceine based on   aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcOCT  a2399-24010 v213 a<p>An efficient asymmetric synthesis of (-)-delta-coniceine via sequential proline-catalyzed asymmetric alpha-amination and Horner-Wadsworth-Emmons olefination of an aldehyde with excellent enantiomeric excess (&gt;99%) and high yields (overall yield 44%) is described. (C) 2010 Elsevier Ltd. All rights reserved.</p>1 aPanchgalle, Sharad, P.1 aBidwai, Harshad, B.1 aChavan, Subhash, P.1 aKalkote, Uttam, R.  uhttps://library.ncl.res.in/content/organocatalytic-asymmetric-synthesis-delta-coniceine-based-sequential-proline-catalyzed-001030nas a2200181   4500008004100000022001400041245006600055210006100121260010600182300001200288490000700300520035100307100002400658700002300682700002300705700002300728856009700751       2011                        eng d  a0040-403900aAsymmetric total synthesis of (2S,3S)-3-hydroxypipecolic acid0 aAsymmetric total synthesis of 2S3S3hydroxypipecolic acid  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcJAN  a404-4060 v523 a<p>A synthetic route to (2S,3S)-3-hydroxypipecolic acid was achieved from readily available nonchiral pool starting material cis-2-butene-1,4-diol and involved Claisen orthoester rearrangement, Sharpless asymmetric dihydroxylation and intramolecular lactamisation of azido lactone as the key steps. (C) 2010 Elsevier Ltd. All rights reserved.</p>1 aChavan, Subhash, P.1 aDumare, Nilesh, B.1 aHarale, Kishor, R.1 aKalkote, Uttam, R.  uhttps://library.ncl.res.in/content/asymmetric-total-synthesis-2s3s-3-hydroxypipecolic-acid-000886nas a2200181   4500008004100000022001400041245006800055210006300123260010600186300001200292490000700304520020100311100002400512700002300536700002300559700002300582856009900605       2011                        eng d  a0957-416600aConvenient formal synthesis of (2S,3S)-3-hydroxy pipecolic acid0 aConvenient formal synthesis of 2S3S3hydroxy pipecolic acid  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcMAR  a587-5900 v223 a<p>A convenient synthesis of (2S,3S)-3-hydroxy pipecolic acid starting from inexpensive and easily available L-(+)-tartaric acid has been described. (C) 2011 Elsevier Ltd. All rights reserved.</p>1 aChavan, Subhash, P.1 aHarale, Kishor, R.1 aDumare, Nilesh, B.1 aKalkote, Uttam, R.  uhttps://library.ncl.res.in/content/convenient-formal-synthesis-2s3s-3-hydroxy-pipecolic-acid-001135nas a2200241   4500008004100000022001400041245010800055210006900163260008600232300001800318490000700336520025300343653001900596653001600615653001800631653001300649653001200662100002700674700002200701700002400723700002300747856012300770       2011                        eng d  a0039-791100aExploration of L-proline-catalyzed -aminoxylation of aldehyde to (S)-guaifenesin-related drug molecules0 aExploration of Lprolinecatalyzed aminoxylation of aldehyde to Sg  a325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USAbTAYLOR & FRANCIS INCcMAY  aPII 9371379300 v413 a<p>[image omitted] An efficient enantioselective synthesis of (S)-guaifenesin with 99% ee using L-proline-catalyzed -aminoxylation of aldehyde as key step is described and explored for asymmetric syntheses of (S)-moprolol and (R)-methocarbamol.</p>10a-Aminoxylation10aguaifenesin10amethocarbamol10amoprolol10aProline1 aPanchgalle, Sharad, P.1 aKunte, Sunita, S.1 aChavan, Subhash, P.1 aKalkote, Uttam, R.  uhttps://library.ncl.res.in/content/exploration-l-proline-catalyzed-aminoxylation-aldehyde-s-guaifenesin-related-drug-001041nas a2200229   4500008004100000022001400041245008300055210006900138260010600207300001400313490000700327520021200334653001500546653001600561653002000577653002900597653001400626100002400640700001900664700002300683856010500706       2012                        eng d  a0040-402000aHighly diastereoselective total synthesis of (+/-)-heritonin and (+/-)-heritol0 aHighly diastereoselective total synthesis of heritonin and herit  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcOCT  a8509-85140 v683 a<p>A highly diastereoselective synthesis of heritol and heritonin by intramolecular cyclization on a preformed sensitive butenolide functionality is described. (C) 2012 Elsevier Ltd. All rights reserved.</p>10aButenolide10acyclization10aDihydroxylation10aFriedel-Crafts acylation10aTetralone1 aChavan, Subhash, P.1 aGarai, Sumanta1 aKalkote, Uttam, R.  uhttps://library.ncl.res.in/content/highly-diastereoselective-total-synthesis-heritonin-and-heritol-001295nas a2200193   4500008004100000022001400041245012000055210006900175260010600244300001200350490000700362520048500369100002500854700002300879700002200902700002300924700002400947856013000971       2015                        eng d  a0957-416600aTotal synthesis of (R)-lipoic acid and (S)-lipoic acid via an Mn (III)-salen-catalyzed oxidative kinetic resolution0 aTotal synthesis of Rlipoic acid and Slipoic acid via an Mn IIIsa  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcMAR  a281-2870 v263 a<p>The asymmetric synthesis of both the antipodes of alpha-lipoic acid is described. The total synthesis of racemic and asymmetric lipoic acid is achieved from propane 1,3-diol. This work reports the use of Mn (III)-salen-catalyzed oxidative kinetic resolution as the key step to obtain enantiomerically pure (R)- and (S)-lipoic acid. The undesired product formed during the resolution can be recycled to achieve the desired isomer. (C) 2015 Elsevier Ltd. All rights reserved.</p>1 aPurude, Abhijeet, N.1 aPawar, Kailash, P.1 aPatil, Niteen, B.1 aKalkote, Uttam, R.1 aChavan, Subhash, P.  uhttps://library.ncl.res.in/content/total-synthesis-r-lipoic-acid-and-s-lipoic-acid-mn-iii-salen-catalyzed-oxidative-kinetic-0