01812nas a2200349   4500008004100000022001400041245014800055210006900203260007700272300001600349490000700365520060800372653001600980653002200996653001501018653001901033653002201052100001701074700002101091700001501112700002401127700002401151700002101175700002201196700002101218700002701239700002201266700002201288700001901310700001601329856011701345       2014                        eng d  a0947-653900aHighly efficient chiral resolution of DL-arginine by cocrystal formation followed by recrystallization under preferential-enrichment conditions0 aHighly efficient chiral resolution of DLarginine by cocrystal fo  aBOSCHSTRASSE 12, D-69469 WEINHEIM, GERMANYbWILEY-V C H VERLAG GMBHcAUG  a10343-103500 v203 a<p>An excellent chiral symmetry-breaking spontaneous enantiomeric resolution phenomenon, denoted preferential enrichment, was observed on recrystallization of the 1:1 cocrystal of dl-arginine and fumaric acid, which is classified as a racemic compound crystal with a high eutectic ee value (&gt;95%), under non-equilibrium crystallization conditions. On the basis of temperature-controlled video microscopy and in situ time-resolved solid-state (CNMR)-C-13 spectroscopic studies on the crystallization process, a new mechanism of phase transition that can induce preferential enrichment is proposed.</p>10aAmino acids10achiral resolution10acocrystals10aCrystal growth10aphase transitions1 aIwama, Sekai1 aKuyama, Kazunori1 aMori, Yuko1 aManoj, Kochunnoonny1 aGonnade, Rajesh, G.1 aSuzuki, Katsuaki1 aHughes, Colan, E.1 aWilliams, Andrew1 aHarris, Kenneth, D. M.1 aVeesler, Stephane1 aTakahashi, Hiroki1 aTsue, Hirohito1 aTamura, Rui  uhttps://library.ncl.res.in/content/highly-efficient-chiral-resolution-dl-arginine-cocrystal-formation-followed-001991nas a2200205   4500008004100000022001400041245013000055210006900185260007100254300001400325490000700339520115900346100003001505700001801535700002201553700002401575700002701599700002801626856013101654       2015                        eng d  a1528-748300aExploiting powder x-ray diffraction to establish the solvent-assisted solid-state supramolecular assembly of pillar[5]quinone0 aExploiting powder xray diffraction to establish the solventassis  a1155 16TH ST, NW, WASHINGTON, DC 20036 USAbAMER CHEMICAL SOCcAPR  a1583-15870 v153 a<p>We report the solvent-mediated supramolecular assembly of pillar[5]quinone (P[5]Q), a symmetric cyclamer containing five benzoquinone moieties bridged by five alternating methylene units. The supramolecular assembly of P[5]Q is shown to be facilitated by 1,1,2,2-tetrachloroethane (TCE) as solvent, producing a microcrystalline solvate material P[5]Q(.)2TCE with a fluffy texture. Optical and electron microscopy reveal that this material has a rod-shaped morphology, extending to several micrometers in length. Due to the microcrystalline nature of the material, structure determination was carried out directly from powder X-ray diffraction data, augmented by high-resolution solid-state C-13 NMR. The two crystallographically distinct TCE molecules occupy different types of void in the structure and have different dynamic properties. Crystallization of P[5]Q was attempted from a large number of different solvents, but only TCE was found to facilitate the formation of a crystalline phase. Indeed, features of the crystal structure suggest that the TCE component plays an important role in promoting the columnar assembly of P[5]Q molecules.</p>1 aShivakumar, Kilingaru, I.1 aYan, Yuncheng1 aHughes, Colan, E.1 aApperley, David, C.1 aHarris, Kenneth, D. M.1 aSanjayan, Gangadhar, J.  uhttps://library.ncl.res.in/content/exploiting-powder-x-ray-diffraction-establish-solvent-assisted-solid-state-supramolecular-1