01237nas a2200157   4500008004100000245007900041210006900120260000800189490000700197520067300204100001800877700002600895700002000921700002700941856011100968       2019                        eng d00aSynthesis of hexaphenylbenzene-based template assembled synthetic proteins0 aSynthesis of hexaphenylbenzenebased template assembled synthetic  cAUG0 v603 a<p>Template-assembled synthetic proteins (TASPs) synthesized from rigid templates have attracted attention due to their interesting structural architectures and potential biomedical applications. Herein, we report the design, synthesis and characterizations of TASPs based on hexaphenylbenzene template (HPB) having twelve peptide attachable axial-arms in its structure. The peptides were attached to all the axial-arms of the template in a single step using simple solution phase peptide coupling strategy. The reaction conditions were standardized systematically using simple amines from smaller size to larger ones. (C) 2019 Elsevier Ltd. All rights reserved.</p>
1 aMadhu, Suresh1 aMadica, Krishnaprasad1 aGonnade, Rajesh1 aSanjayan, Gangadhar, J  uhttps://library.ncl.res.in/content/synthesis-hexaphenylbenzene-based-template-assembled-synthetic-proteins