01887nas a2200205   4500008004100000245018500041210006900226260000800295300002300303490000700326520108700333100001901420700001901439700001701458700001801475700002001493700002001513700001901533856012901552       2019                        eng d00aOne-pot three-component synthesis and photophysical properties of highly fluorescent novel 4-alkyl-3-aryl-2,6-dicyanoanilines by using tris(hydroxymethyl)aminomethane as a catalyst0 aOnepot threecomponent synthesis and photophysical properties of   cFEB  aArticle No: 1001720 v193 aNovel 4-alkyl-3-aryl-2,6-dicyanoanilines were synthesized by a multi-component one-step reaction of aromatic aldehyde, malononitrile and aliphatic aldehyde using tris(hydroxymethyl)aminomethane (THAM) as a catalyst under microwave (MW) irradiation or conventional heating. The optimized reaction condition involved use of 2.5 equivalents of THAM under MW irradiation at 140 W using 20% MW power for 5 min or conventional heating at 80 °C for 8 h in dimethylformamide. The photophysical properties including λmax, quantum yield and Stokes’ shifts of newly synthesized molecules were studied. All compounds exhibited quantum yield in the range of 0.04–0.52 with respect to standard quinine sulphate having quantum yield 0.54. The Stokes’ shifts of all compounds were found in the range of 41–105 nm. The current strategy provides operationally simple protocol using THAM as a catalyst to synthesize 4-alkyl-3-aryl-2,6-dicyanoanilines with diverse structural features to make them available for exploration of their photophysical as well as biological applications.1 aKudale, A., S.1 aKamble, S., B.1 aGore, A., H.1 aPisal, M., M.1 aSalokhe, A., T.1 aKolekar, G., B.1 aHelavi, V., B.  uhttps://library.ncl.res.in/content/one-pot-three-component-synthesis-and-photophysical-properties-highly-fluorescent-novel-4