01836nas a2200289   4500008004100000022001300041245012500054210006900179260000900248300001200257490000600269520088800275653002901163653001301192653001701205653002801222653002501250653001701275100001601292700001301308700001901321700002201340700001801362700001701380700002101397856012801418       2018                        eng d  a2053159100aSurface colonized silver nano particles over chitosan poly-electrolyte micro-spheres and their multi-functional behavior0 aSurface colonized silver nano particles over chitosan polyelectr  cFEB   a 0250320 v53 ahitosan/tripolyphosphate polyelectrolyte (TPP) microspheres, decorated and surface functionalized with silver nanoparticles (NPs) of average diameter of 15 nm, were synthesized following a simple two-step procedure. These Ag NP-functionalized polyelectrolyte microspheres (Ag-CSPMs) are found to be biocompatible and enhancing the reactive oxygen species in curcumin with excellent anti-bacterial activity for selected Gram-positive and negative bacterial strains, making them much attractive relative to bare surface counterparts; the well-stabilized silver NPs do not form any agglomerations on the surface of the chitosan microspheres. They also show excellent cytotoxic behavior towards MCF7 cell lines, showing a half-maximal inhibitory concentration (IC50) of 32 μg ml-1. Therefore, Ag-CSPMs exhibit multi-functional ability having potential towards theranostics applications.10aantibacterial properties10aChitosan10aCytotoxicity10areactive oxygen species10asilver nanoparticles10atheranostics1 aPrakash, B.1 aAsha, S.1 aAnanth, A., N.1 aVanithakumari, G.1 aOkram, G., S.1 aJose, S., P.1 aRajan, M., A. J.  uhttps://library.ncl.res.in/content/surface-colonized-silver-nano-particles-over-chitosan-poly-electrolyte-micro-spheres-and