01186nas a2200181 4500008004100000245013400041210007000175260000800245300001300253490000600266520048100272100002400753700002700777700002200804700002100826700002600847856013100873 2018 eng d00aMetal-free annulation of β-acylamino ketones: facile access to spirooxazolines and oxazolines via oxidative C–O bond formation0 aMetalfree annulation of βacylamino ketones facile access to spir cOCT a544-548 0 v53 aA metal-free annulation reaction of β-acylamino ketone derivatives has been reported for the synthesis of a group of functionalized spirooxazolines and oxazolines in good to excellent yields. The reaction proceeds via phenyliodine(III) diacetate (PIDA)-mediated oxidative C–O bond formation in the presence of BF3–OEt2. The mild reaction conditions, broad substrate scope, simple execution and synthetic potential of the products make this novel protocol very attractive.1 aChavan, Santosh, S.1 aRupanawar, Bapurao, D.1 aKamble, Rohit, B.1 aShelke, Anil, M.1 aSuryavanshi, Gurunath uhttps://library.ncl.res.in/content/metal-free-annulation-%CE%B2-acylamino-ketones-facile-access-spirooxazolines-and-oxazolines00898nas a2200133 4500008004100000245011200041210006900153260000800222520032700230100002700557700002300584700002600607856013100633 2019 eng d00aOxidative Olefination of Benzylamine with an Active Methylene Compound Mediated by Hypervalent Iodine (III)0 aOxidative Olefination of Benzylamine with an Active Methylene Co cSEP3 a

Hypervalent iodine-mediated oxidative olefination of amines with an active methylene compound provides a rapid gateway towards the formation of electrophilic alkenes under mild reaction conditions in good to excellent yields. This is an efficient protocol for the preparation of substituted electrophilic alkenes.

1 aRupanawar, Bapurao, D.1 aVeetil, Sruthi, M.1 aSuryavanshi, Gurunath uhttps://library.ncl.res.in/content/oxidative-olefination-benzylamine-active-methylene-compound-mediated-hypervalent-iodine-iii01248nas a2200193 4500008004100000245012400041210006900165260000800234300001200242490000700254520053100261100002200792700002100814700002700835700002100862700001600883700002600899856012900925 2020 eng d00aTi-superoxide catalyzed oxidative amidation of aldehydes with saccharin as nitrogen source: synthesis of primary amides0 aTisuperoxide catalyzed oxidative amidation of aldehydes with sac cJAN a724-7280 v103 a

A new heterogeneous catalytic system (Ti-superoxide/saccharin/TBHP) has been developed that efficiently catalyzes oxidative amidation of aldehydes to produce various primary amides. The protocol employs saccharin as amine source and was found to tolerate a wide range of substrates with different functional groups. Moderate to excellent yields, catalyst reusability and operational simplicity are the main highlights. A possible mechanism and the role of the catalyst in oxidative amidation have also been discussed.

1 aKamble, Rohit, B.1 aMane, Kishor, D.1 aRupanawar, Bapurao, D.1 aKorekar, Pranjal1 aSudalai, A.1 aSuryavanshi, Gurunath uhttps://library.ncl.res.in/content/ti-superoxide-catalyzed-oxidative-amidation-aldehydes-saccharin-nitrogen-source-synthesis01138nas a2200193 4500008004100000022001400041245009600055210006900151260000800220300001400228490000700242520044500249100002800694700002700722700002100749700002200770700002600792856012600818 2021 eng d a1144-054600aHypervalent iodine(iii) induced oxidative olefination of benzylamines using Wittig reagents0 aHypervalent iodineiii induced oxidative olefination of benzylami cMAY a8806-88130 v453 a

We have developed hypervalent iodine(iii) induced oxidative olefination of primary and secondary benzylamines using 2C-Wittig reagents, which provides easy access to alpha,beta-unsaturated esters. Mild reaction conditions, good to excellent yields with high (E) selectivity, and a broad substrate scope are the key features of this reaction. We have successfully carried out the gram-scale synthesis of alpha,beta-unsaturated esters.

1 aRamavath, Vijayalakshmi1 aRupanawar, Bapurao, D.1 aMore, Satish, G.1 aBansode, Ajay, H.1 aSuryavanshi, Gurunath uhttps://library.ncl.res.in/content/hypervalent-iodineiii-induced-oxidative-olefination-benzylamines-using-wittig-reagents01157nas a2200169 4500008004100000022001400041245014200055210006900197260000900266300001600275490000700291520049000298100002100788700002700809700002600836856012500862 2021 eng d a0022-326300aMetal-free, acid-catalyzed 1,6-conjugate addition of NH-sulfoximines to para-quinone methides: accessing to diarylmethine imino sulfanone0 aMetalfree acidcatalyzed 16conjugate addition of NHsulfoximines t cAUG  a10129-101390 v863 aWe have reported an efficient and metal-free method for the construction of alpha-diarylmethine imino sulfanone using acid-catalyzed 1,6-conjugate addition of sulfoximines on para-quinine methides (p-QMs). This method showed broad functional group tolerance and a wide range of substrate scope with good to excellent yield. The excellent protocol exhibits mild reaction conditions with high atom economy. The practicability of the present method was supported by a Gram-scale reaction.1 aMore, Satish, G.1 aRupanawar, Bapurao, D.1 aSuryavanshi, Gurunath uhttps://library.ncl.res.in/content/metal-free-acid-catalyzed-16-conjugate-addition-nh-sulfoximines-para-quinone-methides01068nas a2200169 4500008004100000022001400041245015800055210006900213260000800282300001600290490000700306520038300313100002700696700002100723700002600744856012800770 2022 eng d a1144-054600aHypervalent-iodine-mediated oxidation followed by the acetoxylation/tosylation of alpha-substituted benzylamines to obtain alpha-acyloxy/tosyloxy ketones0 aHypervalentiodinemediated oxidation followed by the acetoxylatio cSEP a16832-168390 v463 a

An efficient and metal-free method has been developed for the sequential oxidation of alpha-alkylbenzylamines followed by acetoxylation or tosylation for the synthesis of alpha-acyloxy/tosyloxy ketones using hypervalent iodine(iii). The employment of a simple starting material, broad substrate scope and operational simplicity are the key features of this protocol.

1 aRupanawar, Bapurao, D.1 aMane, Kishor, D.1 aSuryavanshi, Gurunath uhttps://library.ncl.res.in/content/hypervalent-iodine-mediated-oxidation-followed-acetoxylationtosylation-alpha-substituted01140nas a2200229 4500008004100000022001400041245011400055210006900169260000800238300001500246490000900261520038300270653001300653653000800666653000800674653001500682653001200697100002100709700002700730700002600757856012700783 2022 eng d a1434-193X00aVisible light-promoted, photocatalyst-free C(sp(2))-H bond functionalization of indolizines via EDA complexes0 aVisible lightpromoted photocatalystfree Csp2H bond functionaliza cMAY ae2022002610 v20223 a

The catalyst and additive-free, photo-driven cross dehydrogenative coupling (CDC) reaction initiated by electron donor-acceptor (EDA) complexes between electron rich indolizines and electron poor quinones has been demonstrated. This green transformation reveals the advantages of operational simplicity, mild reaction conditions and good functional group tolerances.

10aBlue LED10aCDC10aEDA10aIndolizine10aQuinone1 aMane, Kishor, D.1 aRupanawar, Bapurao, D.1 aSuryavanshi, Gurunath uhttps://library.ncl.res.in/content/visible-light-promoted-photocatalyst-free-csp2-h-bond-functionalization-indolizines-eda01434nas a2200229 4500008004100000022001400041245011900055210006900174260000800243300001200251490000700263520064000270653002000910653001100930653002300941653001600964653001400980100002700994700002201021700002601043856013501069 2025 eng d a0936-521400aHypervalent-iodine-mediated base-free oxidative olefination of benzylic amines to access α,β-unsaturated ketones0 aHypervalentiodinemediated basefree oxidative olefination of benz cAUG a556-5600 v363 a

We report a one-pot base-free protocol for the oxidative olefination of benzylic amines promoted by a hypervalent iodine reagent for the synthesis of alpha,beta-unsaturated ketones. Mechanistically, (diacetoxyiodo)benzene oxidizes the benzylic amine to the corresponding imine, which, on reaction with a phenacyl(triphenyl)phosphonium bromide salt and an in situ generated acetoxy anion leads to an alpha,beta-unsaturated ketone. A wide range of alpha,beta-unsaturated ketones were easily accessed through direct oxidative olefination of substituted benzylic amines in good to excellent yields and with high E -selectivity.

10abenzylic amines10aenones10ahypervalent iodine10aolefination10aOxidation1 aRupanawar, Bapurao, D.1 aBansode, Ajay, H.1 aSuryavanshi, Gurunath uhttps://library.ncl.res.in/content/hypervalent-iodine-mediated-base-free-oxidative-olefination-benzylic-amines-access-%CE%B1%CE%B2