01385nas a2200193   4500008004100000022001400041245011000055210006900165260007100234300001400305490000700319520061700326100002500943700002900968700002500997700001601022700002501038856012801063       2015                        eng d  a1523-706000aAsymmetric transfer hydrogenation of imines in water by varying the ratio of formic acid to triethylamine0 aAsymmetric transfer hydrogenation of imines in water by varying   a1155 16TH ST, NW, WASHINGTON, DC 20036 USAbAMER CHEMICAL SOCcJUN  a2878-28810 v173 a<p>Asymmetric transfer hydrogenation (ATH) of imines has been performed with variation in formic acid (F) and triethylamine (T) molar ratios in water. The F/T ratio is shown to affect both the reduction rate and enantioselectivity, with the optimum ratio being 1.1 in the ATH of imines with the Rh-(1S,2S)-TsDPEN catalyst. Use of methanol as a cosolvent enhanced reduction activity. A variety of imine substrates have been reduced, affording high yields (94-98%) and good to excellent enantioselectivities (89-98%). In comparison with the common azeotropic F-T system, the reduction with 1.1/1 F/T is faster.</p>1 aShende, Vaishali, S.1 aDeshpande, Sudhindra, H.1 aShingote, Savita, K.1 aJoseph, Anu1 aKelkar, Ashutosh, A.  uhttps://library.ncl.res.in/content/asymmetric-transfer-hydrogenation-imines-water-varying-ratio-formic-acid-triethylamine-0