01465nas a2200253   4500008004100000022001400041245007100055210006900126260008600195300001400281490000700295520057100302653001800873653002400891653002800915653003000943653002800973100002401001700002101025700001901046700002401065700002101089856010101110       2015                        eng d  a1860-539700aSynthesis of novel N-cyclopentenyl-lactams using the aube reaction0 aSynthesis of novel Ncyclopentenyllactams using the aube reaction  aTRAKEHNER STRASSE 7-9, FRANKFURT AM MAIN, 60487, GERMANYbBEILSTEIN-INSTITUTcJUN  a1060-10670 v113 a<p>A novel and convenient method utilizing the Aube reaction to access a new class of compounds that are similar to carbocyclic nucleosides is reported. The azido alcohol derived from Vince lactam undergoes the Aube reaction with various cyclic ketones to give cyclopentenyl-substituted lactams. Upon dihydroxylation, this affords the N-cyclopentenyl-lactam compounds in racemic form. Given the numerous uses of nucleosides and related compounds, we were interested in the synthesis of carbocylic nucleoside mimics. The attempts and results are described herein.</p>10aAube reaction10aBiological activity10acarbocyclic nucleosides10acyclopentenylated lactams10acyclopentylated lactams1 aShinde, Madhuri, V.1 aOple, Rohini, S.1 aSangtani, Ekta1 aGonnade, Rajesh, G.1 aReddy, Srinivasa  uhttps://library.ncl.res.in/content/synthesis-novel-n-cyclopentenyl-lactams-using-aube-reaction-001266nas a2200229   4500008004100000022001400041245004500055210004100100260007500141300001400216520054600230653001600776653002100792653002200813653002100835653002000856100002100876700002400897700002100921700002100942856007300963       2016                        eng d  a1434-193X00aTotal synthesis of (-)-nardoaristolone B0 aTotal synthesis of nardoaristolone B  aPOSTFACH 101161, 69451 WEINHEIM, GERMANYbWILEY-V C H VERLAG GMBHcAUG  a3804-38083 a<p>A stereoselective total synthesis of (-)-Nardoaristolone B, a nor-aristolane sesquiterpenoid natural product with an unusual 3/5/6 tricyclic ring system is described. The highlights of the present work includes use of (+)-(R)-Pulegone as a chiral-pool starting material, ring-closing metathesis, allylic oxidation and stereoselective cyclopropanation. In addition, a new analogue of Nardoaristolone B (minor product from the final step) was isolated in pure form and fully characterized with the help of single-crystal X-ray analysis.</p>10aChiral pool10acyclopropanation10aNardoaristolone B10aNatural products10aTotal synthesis1 aOple, Rohini, S.1 aHandore, Kishor, L.1 aKamat, Nidhi, S.1 aReddy, Srinivasa  uhttps://library.ncl.res.in/content/total-synthesis-nardoaristolone-b