01414nas a2200169 4500008004100000022001400041245015600055210006900211260000800280300001200288490000700300520073800307100002701045700002401072700002601096856012201122 2018 eng d a1477-052000aEosin Y photoredox catalyzed net redox neutral reaction for regiospecific annulation to 3-sulfonylindoles via anion oxidation of sodium sulfinate salts0 aEosin Y photoredox catalyzed net redox neutral reaction for regi cJAN a536-5400 v163 a

An eosin Y photoredox catalyzed net redox neutral process for 3-sulfonylindoles via the anionic oxidation of sodium sulfinate salts and its radical cascade cyclization with 2-alkynyl-azidoarenes was developed with visible light as a mediator. The reaction offers metal and oxidant/reductant free, visible light mediated vicinal sulfonamination of alkynes to 2-aryl/alkyl-3-sulfonylindoles and proceeds via the generation of a sulfur-centered radical through direct oxidation of the sulfinate anion by an excited photocatalyst with a reductive quenching cycle. The mild conditions, use of an organic dye as photo-catalyst, bench stability and easily accessible starting materials make the present approach green and attractive.

1 aRohokale, Rajendra, S.1 aTambe, Shrikant, D.1 aKshirsagar, Umesh, A. uhttps://library.ncl.res.in/content/eosin-y-photoredox-catalyzed-net-redox-neutral-reaction-regiospecific-annulation-301272nas a2200157 4500008004100000245014100041210006900182260000800251300001500259520061400274100002400888700002300912700002700935700002600962856012600988 2018 eng d00aMetal-free synthesis of 3-thiocyanatobenzothiophenes by eosin Y photoredox-catalyzed cascade radical annulation of 2-alkynylthioanisoles0 aMetalfree synthesis of 3thiocyanatobenzothiophenes by eosin Y ph cSEP a 4867-48733 a

A convenient, efficient, metal-free synthesis of 3-thiocyanatobenzothiophenes has been developed that uses eosin Y in a visible-light-mediated photoredox-catalyzed anion oxidation of the ammonium salt of thiocyanate and proceeds through the cascade radical annulation of 2-alkynylthioanisole at room temperature. The present protocol requires visible light as a green energy source, an organic dye as the photocatalyst, and oxygen as a green oxidant to provide a mild route with a broad substrate scope for the formation of potentially bioactive 3-substituted benzothiophene derivatives in good yields.

1 aTambe, Shrikant, D.1 aJadhav, Mahesh, S.1 aRohokale, Rajendra, S.1 aKshirsagar, Umesh, A. uhttps://library.ncl.res.in/content/metal-free-synthesis-3-thiocyanatobenzothiophenes-eosin-y-photoredox-catalyzed-cascade01278nas a2200145 4500008004100000245016200041210006900203260000800272300001400280520063200294100002400926700002700950700002600977856012901003 2018 eng d00aVisible-light-mediated eosin Y photoredox-catalyzed vicinal thioamination of alkynes: radical cascade annulation strategy for 2-substituted-3-sulfenylindoles0 aVisiblelightmediated eosin Y photoredoxcatalyzed vicinal thioami cMAY a2117-21213 aAn organic dye photoredox-catalyzed regiospecific radical cascade annulation strategy of 2-alkynyl-azidoarenes to generate 3-sulfenylindoles via vicinal thioamination of alkynes at room temperature, mediated by visible light, was developed. The method requires mild conditions, including visible light as a traceless green energy source, room temperature, eosin Y organic dye as a photoredox catalyst, ambient air as oxidant, and easily available starting materials to provide a green, efficient, metal- and strong-oxidant-free synthesis of 3-sulfenylindoles with broad substrate scope through vicinal thioamination of alkynes.1 aTambe, Shrikant, D.1 aRohokale, Rajendra, S.1 aKshirsagar, Umesh, A. uhttps://library.ncl.res.in/content/visible-light-mediated-eosin-y-photoredox-catalyzed-vicinal-thioamination-alkynes-radical01069nas a2200169 4500008004100000022001400041245010800055210006900163260000900232300001400241490000700255520042800262100002700690700002600717700002400743856013200767 2019 eng d a0022-326300aIridium(III)-catalyzed alkynylation of 2-(Hetero)arylquinazolin-4-one scaffolds via C-H bond activation0 aIridiumIIIcatalyzed alkynylation of 2Heteroarylquinazolin4one sc cMAR  a2951-29610 v843 a

The directed C-H alkynylation of 2-(hetero)arylquinazolin-4-ones has been explored with the ethynylbenziodoxolone reagent TIPS-EBX employing an Ir(III) catalyst. Complementary conditions for either monoalkynylation or dialkynylation have been developed. Also demonstrated is the broad scope of this reaction and the compatibility of various functional groups such as -F, -Cl, -Br, -CF3, -OMe, -NO2, and alkyl, etc.

1 aRohokale, Rajendra, S.1 aKalshetti, Rupali, G.1 aRamana, Chepuri, V. uhttps://library.ncl.res.in/content/iridiumiii-catalyzed-alkynylation-2-heteroarylquinazolin-4-one-scaffolds-c-h-bond-activation