01354nas a2200241   4500008004100000022001400041245009000055210006900145260010600214300001400320490000700334520044400341653001800785653002800803653003100831653001900862100002200881700002400903700001900927700001500946700002700961856012400988       2013                        eng d  a0960-894X00aSynthesis and antitubercular activity of amino alcohol fused spirochromone conjugates0 aSynthesis and antitubercular activity of amino alcohol fused spi  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcMAR  a1416-14190 v233 a<p>A series of 21 new amino alcohol fused spirochromone conjugates have been synthesized, characterized with analytical data and evaluated their antimycobacterial activity against Mycobacterium tuberculosis (virulent strain H37Rv) in vitro. Some of the compounds exerted significant inhibition, in particular, compound 4f found to be the most potent derivative exhibiting MIC = 3.13 mu g/mL. (C) 2013 Elsevier Ltd. All rights reserved.</p>10aAmino alcohol10aAntitubercular activity10aMycobacterium tuberculosis10aSpirochromones1 aMujahid, Mohammad1 aGonnade, Rajesh, G.1 aYogeeswari, P.1 aSriram, D.1 aMuthukrishnan, Murugan  uhttps://library.ncl.res.in/content/synthesis-and-antitubercular-activity-amino-alcohol-fused-spirochromone-conjugates-0