01165nas a2200217   4500008004100000022001400041245008600055210006900141260007500210300001400285490000600299520037200305653003700677653002800714653001600742653001100758653002700769100001900796700001900815856011300834       2011                        eng d  a0039-788100aEfficient convergent access to spiroketal segment of (+)-spiroxaline methyl ether0 aEfficient convergent access to spiroketal segment of spiroxaline  aRUDIGERSTR 14, D-70469 STUTTGART, GERMANYbGEORG THIEME VERLAG KGcAPR  a1137-11410 v23 a<p>Starting from trimethylsilylacetylene, a facile synthesis of optically pure spiroketal unit of (+)-spiroxaline methyl ether has been described. The synthesis entails stepwise alkylation and acylation of an alkyne with two different readily available chiral building blocks followed by the reductive in situ regio- and stereoselective spiroketalization pathway.</p>10a(+)-spiroketal segment synthesis10a(R)-gamma-valerolactone10a(R)-oxirane10aalkyne10anucleophilic reactions1 aSingh, Mandeep1 aArgade, N., P.  uhttps://library.ncl.res.in/content/efficient-convergent-access-spiroketal-segment-spiroxaline-methyl-ether-001406nas a2200253   4500008004100000022001400041245008000055210006900135260007500204300001400279490000700293520052000300653003500820653001600855653002900871653001400900653002700914653002000941100002400961700002200985700002101007700001901028856010501047       2014                        eng d  a0039-788100aConcise account of the chemistry of valuable alkyl(methyl)maleic anhydrides0 aConcise account of the chemistry of valuable alkylmethylmaleic a  aRUDIGERSTR 14, D-70469 STUTTGART, GERMANYbGEORG THIEME VERLAG KGcOCT  a2683-27000 v463 a<p>A large number of significant bioactive natural and synthetic alkyl(methyl)maleic anhydrides are known in the contemporary literature. A broad range of suitably functionalized substrates have been tailored to accomplish concise and efficient syntheses of an array of alkyl(methyl)maleic anhydrides employing a variety of elegant synthetic strategies. This review presents a brief literature account of the isolation and activity of these important target compounds with a special emphasis on their synthesis.</p>10aalkyl(methyl)maleic anhydrides10abioactivity10adimethylmaleic anhydride10aisolation10anucleophilic reactions10aTotal synthesis1 aDeore, Prashant, S.1 aHaval, Kishan, P.1 aGadre, Smita, R.1 aArgade, N., P.  uhttps://library.ncl.res.in/content/concise-account-chemistry-valuable-alkylmethylmaleic-anhydrides-0