02296nas a2200229   4500008004100000245014400041210006900185260000800254300000800262520150000270653001301770653001101783653002401794653001201818100001601830700001601846700001801862700001801880700001801898700001901916856013101935       2017                        eng d00aRemoval of endrin and dieldrin isomeric pesticides through stereoselective adsorption behavior on the graphene oxide-magnetic nanoparticles0 aRemoval of endrin and dieldrin isomeric pesticides through stere  cSEP  a1-93 a<p>A novel stereoselective removal behavior of isomeric endrin and dieldrin pesticides from sample solution is demonstrated using nanocomposite of graphene oxide (GO) and iron oxide (Fe3O4) magnetic nanoparticles (MNPs). The removal efficiency of endrin and dieldrin was found higher when GO-MNPs was used as a separating probe than the individual use of GO and MNPs. The removal efficiency of both the pesticides was found to be more favorable when the dosage amount of GO-MNPs was 30 mg for 30-min contact time with pH 4.0 at room temperature. The good correlation of determination (R2) with 0.975 and 0.973 values obtained for endrin and dieldrin, respectively demonstrated a well fitting of Langmuir adsorption isotherm model. The higher removal percentage (86.0%) and higher slope value of Langmuir adsorption isotherm were estimated for endrin compared to dieldrin (74.0%). The reason for higher adsorption percentage of endrin is due to the endo-position of oxygen atom in molecule favors more interaction of molecules with GO-MNPs compared to the exo-position of oxygen present in dieldrin. In addition, the higher value of R2 for endrin and dieldrin demonstrated better suitability of pseudo-first-order and pseudo-second-order kinetic models, respectively. The advantages of the present method are use of simple UV-vis spectrophotometry for monitoring and low-cost use of GO-MNPs nanomaterial for the removal of pesticides from sample solution. © 2017 Springer-Verlag GmbH Germany</p>10aDieldrin10aEndrin10aIsomeric Pesticides10aRemoval1 aShrivas, K.1 aGhosale, A.1 aNirmalkar, N.1 aSrivastava, A1 aSingh, S., K.1 aShinde, S., S.  uhttps://library.ncl.res.in/content/removal-endrin-and-dieldrin-isomeric-pesticides-through-stereoselective-adsorption-behavior02322nas a2200181   4500008004100000022002100041245007100062210006900133260001400202300001200216520172200228100001901950700001801969700001801987700001802005700001802023856009902041       2017                        eng d  a 978-149873419-600aSynthesis of fluorinated heterocycles via multicomponent reactions0 aSynthesis of fluorinated heterocycles via multicomponent reactio  bCRC Press  a183-1993 aFluorine is one of the most important elements in the periodic table because it is the most electronegative element, makes the strongest C-F bond, and is more polarized in organic synthesis. These unique and distinctive properties of fluorine make it very useful and widely applicable in the pharmaceutical and agrochemical industries. Hydrogen replaced with the fluorine of an organic compound can tune the pharmacokinetic and pharmacological properties of the molecule, which improve solubility, membrane permeability, 184metabolic stability, and receptor-binding properties compared with nonfluorinated analogs.1 Due to these unique properties of fluorine, organofluorine compounds are very applicative in medicinal, pharmaceutical, agrochemical, and material chemistry. This wide applicability of fluorine and organofluorine compounds attracts the attention of researchers and chemists. Labeled fluorine-18 is one of the most commonly used positron emitting radioisotopes in positron emission tomography (PET) imaging technology, which can detect presymptomatic biochemical changes in body tissues. In addition to its use in PET-CT, fluorine is used in preparation of chemically resistant polymer materials such as polytetrafluoroethylene (Teflon) or polarity to piezoelectric material such as polyvinylidene fluoride and organic liquid crystals for displays. Because of these many advantages of fluorine, organic chemists have developed various methods to introduce fluorine in organic molecules. During the last two decades, numerous organofluorine heterocyclics have been developed; in this chapter, we have summarized synthesis of multicomponent reactions (MCRs) in application of fluorine compound synthesis.1 aShinde, S., S.1 aThore, S., N.1 aPawar, R., P.1 aAmeta, K., L.1 aPatil, S., N.  uhttps://library.ncl.res.in/content/synthesis-fluorinated-heterocycles-multicomponent-reactions01751nas a2200157   4500008004100000245018200041210006900223300001400292490000800306520108200314100001401396700001901410700001901429700001401448856013101462       2018                        eng d00aCatalytic and efficient synthesis of optically active terminal epoxides and 1,2-diols using a new lanthanum triflate assisted C1-symmetric bimetallic chiral salen cobalt complex0 aCatalytic and efficient synthesis of optically active terminal e  a960 - 9660 v15 3 aThe catalytic asymmetric synthesis of terminal epoxides and 1,2-diols via a hydrolytic kinetic resolution of racemic terminal epoxides using a new bimetallic chiral salen CoIII complex incorporated with La(OTf)3 as a catalyst is reported. The new bimetallic chiral salen CoIII complex bearing La(OTf)3 was prepared in a one-pot procedure by activation and bimetallic complex formation from the inactive Jacobsen chiral salen CoII complex (salen = N, N′-bis(3,5-di-tert-butylsalicylidene)-1,2- cyclohexane-diamine). We observed that C1-symmetric chiral bimetallic Co-complex coordinated with La(OTf)3 works as a chiral catalyst and remarkably increased the reactivity and enantioselectivity in the hydrolytic kinetic resolution of terminal epoxides compared to its monometallic analogues. La(OTf)3 plays a crucial role as an achiral Lewis acid in this process, which is supported by the experimental observation presented. To explore the absolute configuration of glycidyl butyrate a vibrational circular dichroism (VCD) spectra was calculated using density functional theory.1 aPatel, D.1 aThakur, S., S.1 aShinde, S., S.1 aKumar, P.  uhttps://library.ncl.res.in/content/catalytic-and-efficient-synthesis-optically-active-terminal-epoxides-and-12-diols-using-new01104nas a2200169   4500008004100000020001300041245011100054210006900165260000800234300001400242490000900256520048900265100002000754700001800774700001900792856012300811       2018                        eng d  a1434193X00aOne-pot sequential bromination and fluorination to access 3-fluoroimidazo[1,2-a]pyridines from arylketones0 aOnepot sequential bromination and fluorination to access 3fluoro  cJUL  a3432-34360 v20183 a3-Fluoro-2-arylimidazo[1,2-a]pyridines were selectively synthesised in one-pot from acetophenones and 2-aminopyridines under mild conditions. The sequence of reactions involved bromination, condensation, and late-stage fluorination. Two halogenating reagents play key roles in the process. We found that tetrabutylammonium tribromide and SelectfluorTM gave excellent yields of the desired products in the one-pot sequential reaction. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim1 aUdavant, R., N.1 aYadav, A., R.1 aShinde, S., S.  uhttps://library.ncl.res.in/content/one-pot-sequential-bromination-and-fluorination-access-3-fluoroimidazo12-apyridines