01537nas a2200361 4500008004100000022001400041245007800055210006900133260000800202300001400210490000700224520045500231653002800686653001300714653001400727653001100741653001300752653002000765653002100785653003900806653002400845653002600869653001200895653001700907653001900924653002300943653002500966100002000991700001801011700001801029700002501047856010301072 2017 eng d a0039-788100aSimple cobalt(II) chloride catalyzed N-alkylation of amines with alcohols0 aSimple cobaltII chloride catalyzed Nalkylation of amines with al cSEP a3957-39610 v493 a

A facile cobalt-catalyzed N-alkylation of amines with alcohols using inexpensive, commercially available CoCl2 center dot 6H(2)O is reported. Employing this readily available cobalt catalyst, a variety of amines with wide functional group tolerance were selectively alkylated under benign conditions.

10a(Hetero)Aromatic Amines10aAlcohols10aAmination10aamines10aAnilines10aAromatic-amines10aCobalt Catalysis10aDehydrogenation Borrowing Hydrogen10aEfficient Catalysts10aHydrogen Autotransfer10aIridium10aN-alkylation10aPincer-complex10aSecondary Alcohols10aSelective Alkylation1 aMidya, Siba, P.1 aMondal, Akash1 aBegum, Ayesha1 aBalaraman, Ekambaram uhttps://library.ncl.res.in/content/simple-cobaltii-chloride-catalyzed-n-alkylation-amines-alcohols00939nas a2200193 4500008004100000022001400041245009100055210006900146260000800215300001400223490000700237520027300244100002200517700001800539700001700557700002900574700002500603856011700628 2018 eng d a1477-052000aManganese catalyzed N-alkylation of anilines with alcohols: ligand enabled selectivity0 aManganese catalyzed Nalkylation of anilines with alcohols ligand cNOV a8175-81800 v163 aLigand enabled Earth-abundant manganese catalyzed N-alkylation of amines with alcohols via a hydrogen auto-transfer strategy is reported. The choice of the ligand plays a significant role in the alcohol reactivity (aliphatic or aromatic) toward N-alkylation reactions.1 aLandge, Vinod, G.1 aMondal, Akash1 aKumar, Vinit1 aNandakumar, Avanashiappn1 aBalaraman, Ekambaram uhttps://library.ncl.res.in/content/manganese-catalyzed-n-alkylation-anilines-alcohols-ligand-enabled-selectivity01028nas a2200181 4500008004100000022001400041245008300055210006900138260000800207300001400215490000700229520040800236100001800644700002600662700003000688700002400718856010400742 2018 eng d a1523-706000aManganese-catalyzed direct conversion of ester to amide with liberation of H 20 aManganesecatalyzed direct conversion of ester to amide with libe cJUN a3381-33840 v203 a

A simple and efficient Mn-catalyzed acylation of amines is achieved using both acyl and alkoxy functions of unactivated esters with the liberation of molecular hydrogen as a sole byproduct. The present protocol provides an atom-economical and sustainable route for the synthesis of amides from esters by employing an earth-abundant manganese salt and inexpensive phosphine-free tridentate ligand.

1 aMondal, Akash1 aSubaramanian, Murugan1 aAvanashiappan, Nandakumar1 aBalaraman, Kambaram uhttps://library.ncl.res.in/content/manganese-catalyzed-direct-conversion-ester-amide-liberation-h-2