01075nas a2200193 4500008004100000245009800041210006900139260000800208300001400216490000700230520037400237100002400611700002400635700002400659700002600683700002100709700002600730856012500756 2017 eng d00aEfficient Sn(II)-catalyzed one-pot synthesis of a 3-substituted azetidine-2,4-dione framework0 aEfficient SnIIcatalyzed onepot synthesis of a 3substituted azeti cMAR a2385-23910 v153 aA novel Sn(II)-catalyzed tandem cyclization reaction of aromatic aldehydes with ethyl cyanoacetate has been achieved to afford a series of 3-substituted azetidine-2,4-diones in good to excellent yields. This protocol provides straightforward access to construct the azetidine core through sequential Knoevenagel condensation, hydration and the C-N cyclization reaction.1 aChavan, Santosh, S.1 aSupekar, Mrudul, V.1 aBurate, Pralhad, A.1 aRupanwar, Bapurao, D.1 aShelke, Anil, M.1 aSuryavanshi, Gurunath uhttps://library.ncl.res.in/content/efficient-snii-catalyzed-one-pot-synthesis-3-substituted-azetidine-24-dione-framework01828nas a2200145 4500008004100000245011600041210006900157260000800226520122000234100002601454700002201480700002401502700002601526856013001552 2019 eng d00aAgNO3-Catalysed intramolecular cyclization: access to functionalized cyclopentanones and spiro-cyclopentanones 0 aAgNO3Catalysed intramolecular cyclization access to functionaliz cAUG3 a

An efficient AgNO3-catalysed method has been developed for the synthesis of functionalized cyclopentanones and spiro-cyclopentanones through intramolecular cyclization between ynones and cyanoacrylate/aryl/alkylidene malononitrile using DBU as a base. Easy availability of starting materials and mild reaction conditions makes this protocol more feasible over previously reported methods. The functionalized cyclopentanones and spiro-cyclopentanones were synthesized in good to excellent yields with a broad substrate scope.

1 aBhoite, Shubhangi, P.1 aBansode, Ajay, H.1 aBurate, Pralhad, A.1 aSuryayanshi, Gurunath uhttps://library.ncl.res.in/content/agno3-catalysed-intramolecular-cyclization-access-functionalized-cyclopentanones-and-spiro01562nas a2200253 4500008004100000022001400041245013400055210006900189260000800258300001400266490000800280520068000288653001800968653002100986653001801007653001701025653002901042653001701071100002401088700002501112700002401137700002101161856012601182 2019 eng d a1011-372X00aAmino acid amide based ionic liquid as an efficient organo-catalyst for solvent-free knoevenagel condensation at room temperature0 aAmino acid amide based ionic liquid as an efficient organocataly cSEP a2368-23750 v1493 a

Ionic liquids of amino acid amide were synthesized and used as an efficient catalyst for solvent-free Knoevenagel condensation. Synthesized ionic liquids are an environmentally benign, inexpensive, metal free and plays the dual role of solvent as well as an efficient catalyst for Knoevenagel condensation. A wide range of aliphatic, aromatic and heteroaromatic aldehydes easily undergo condensation with malononitrile and ethyl cyanoacetate. The reaction proceeds at room temperature without using any organic solvent and is very fast with good to excellent yield. Additionally, the catalyst is easily separable and recyclable without loss of activity. [GRAPHICS] .

10aAcrylonitrile10aAmino acid amide10aCyanoacrylate10aIonic liquid10aKnoevenagel condensation10aSolvent-free1 aBurate, Pralhad, A.1 aJavle, Balasaheb, R.1 aDesale, Pranjal, H.1 aKinage, Anil, K. uhttps://library.ncl.res.in/content/amino-acid-amide-based-ionic-liquid-efficient-organo-catalyst-solvent-free-knoevenagel